FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(2R)mir-309-6Δ1
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General Information
Symbol
Df(2R)mir-309-6Δ1
Species
D. melanogaster
Name
FlyBase ID
FBab0046035
Feature type
chromosomal_deletion
Also Known As
miR-309-6Δ1
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
recombination
(Bushati et al., 2008)
Class of aberration (relative to wild type)
chromosomal_deletion
(Bushati et al., 2008)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Bushati et al., 2008)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
TI{GFP}Df-mir-309-6-Δ1
(Bushati et al., 2008)
Formalized genetic data
Genetic mapping information
Comments

Ends-out homologous recombination has resulted in 1.1kb comprising the "mir-309" cluster containing eight miRNA genes (mir-6-3, mir-6-2, mir-6-1, mir-5, mir-4, mir-286, mir-3 and mir-309) being replaced with a Avic\GFP marker.

(Bushati et al., 2008)
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations

    Df(2R)mir-309-6Δ1/Df(2R)ED3728 animals show partial lethality. Df(2R)mir-309-6Δ1/Df(2R)ED3728 embryos show a significant increase in primordial germ cell number compared to controls.

    (Chen et al., 2014)
    NOT in combination with other aberrations

    Homozygotes show partial lethality. Homozygous males and females are fertile.

    (Chen et al., 2014)

    Homozygous Df(2R)mir-309-6Δ1 animals show a modest reduction in viability to adulthood. Homozygous Df(2R)mir-309-6Δ1 mutants show little or no reduction in the completion of embryogenesis compared to controls.

    (Ge et al., 2012)

    Homozygotes complete embryogenesis with no apparent defects in patterning, but approximately 20% die as larvae at different larval stages. Some animals stop growing at the size of second instar larvae and arrest at this stage for a few days before dying. Approximately 80% of homozygotes survive to adulthood and are viable and fertile. The mutant animals show a developmental delay during larval stages.

    (Bushati et al., 2008)
    Stocks (1)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (6)
    Reported As
    Symbol Synonym
    6-cl
    (Ge et al., 2012)
    Df(2R)mir-309-6Δ1
    miR-309-6Δ1
    (Bushati et al., 2008)
    mir-309-6Δ1
    (Hanyu-Nakamura et al., 2019)
    mir-309-C delta 1
    (Zhou et al., 2018)
    mir-3Δ
    (Kingston et al., 2022)
    Name Synonyms
    Secondary FlyBase IDs
      References (8)