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General Information
D. melanogaster
FlyBase ID
Feature type
Also Known As
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Causes alleles
Carries alleles
Formalized genetic data
Genetic mapping information

Ends-out homologous recombination has resulted in 1.1kb comprising the "mir-309" cluster containing eight miRNA genes (mir-6-3, mir-6-2, mir-6-1, mir-5, mir-4, mir-286, mir-3 and mir-309) being replaced with a Avic\GFP marker.

Comments on Cytology
Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
Molecular Data
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    Df(2R)mir-309-6Δ1/Df(2R)ED3728 animals show partial lethality. Df(2R)mir-309-6Δ1/Df(2R)ED3728 embryos show a significant increase in primordial germ cell number compared to controls.

    NOT in combination with other aberrations

    Homozygotes show partial lethality. Homozygous males and females are fertile.

    Homozygous Df(2R)mir-309-6Δ1 animals show a modest reduction in viability to adulthood. Homozygous Df(2R)mir-309-6Δ1 mutants show little or no reduction in the completion of embryogenesis compared to controls.

    Homozygotes complete embryogenesis with no apparent defects in patterning, but approximately 20% die as larvae at different larval stages. Some animals stop growing at the size of second instar larvae and arrest at this stage for a few days before dying. Approximately 80% of homozygotes survive to adulthood and are viable and fertile. The mutant animals show a developmental delay during larval stages.

    Stocks (1)
    Notes on Origin
    Balancer / Genotype Variants of the Aberration
    Separable Components
    Other Comments
    Synonyms and Secondary IDs (5)
    Reported As
    Symbol Synonym
    mir-309-C delta 1
    Name Synonyms
    Secondary FlyBase IDs
      References (6)