Deletion extending from 973bp upstream of the sphe start site to 1807bp downstream of the sphe start site (revision of data in FBrf0237463). The junction sequences are TTTATTT/TTTTATACA (upstream) and CCAGTC/ATGTTA (downstream).
Df(1)spheΔ49 mutants show significantly increased mortality upon infection with the Gram-positive bacterium Enterococcus faecalis, but not upon infection with the entomopathogenic fungus Beauveria bassiana, as compared to controls.