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General Information
Symbol
Dmel\ctMR2
Species
D. melanogaster
Name
FlyBase ID
FBal0002042
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Insertion of gypsy element at nucleotide position -118.

DNA coordinates (Jack, 1985) (0 is gypsy site in ct6): 0

Insertion components
gypsy{}ct-MR2
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Wings are cut to points, and the wing margins are scalloped.

Strong ct6-like wing phenotype.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference
Phenotype Manifest In
Suppressed by
Statement
Reference

ctMR2 has phenotype, suppressible by su(Hw)2

ctMR2 has phenotype, suppressible by su(Hw)u1

ctMR2 has phenotype, suppressible by su(Hw)u2

Additional Comments
Genetic Interactions
Statement
Reference

Phenotype is partially suppressed by mod(mdg4)ul at 25oC, and completely suppressed by mod(mdg4)ul at 18oC.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Highly unstable; mutates to either stable, unstable (most frequent, --> 10-4 mutations to ct), or superunstable (least frequent, --> around 50% ct mutants) alleles and to other ct alleles, which in turn may be unstable or superunstable. The gypsy sequence appears to be mobilized and transposed into other parts of the ct locus to produce new ct alleles or, when ct undergoes reversion, to other positions on the chromosomes where new mutants arise.

Other types of transposing elements also appear to be mobilized in the ctMR2 unstable system.

Unstable revertants are able to generate new ct derivatives, retain the gypsy LTR of ctMR2.

ctMR2 can revert or partially revert by excision of, or insertion of other elements (e.g. jockey or Hercules), into the gypsy insert responsible for ctMR2.

su(Hw) binding site in gypsy insertion in ct is full length.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
ctMR2
Name Synonyms
Secondary FlyBase IDs
    References (13)