FB2026_02 , released June 18, 2026
Allele: Dmel\ctMR2
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General Information
Symbol
Dmel\ctMR2
Species
D. melanogaster
Name
FlyBase ID
FBal0002042
Feature type
allele
Associated gene
Dmel\ct
Associated Insertion(s)
gypsy{}ct-MR2
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
MRh12 induced male recombination
Progenitor genotype
Associated Insertion(s)
gypsy{}ct-MR2
Cytology
Description

Insertion of gypsy element at nucleotide position -118.

(Tchurikov et al., 1989)

DNA coordinates (Jack, 1985) (0 is gypsy site in ct6): 0

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Wings are cut to points, and the wing margins are scalloped.

      (Georgiev and Gerasimova, 1989)

      Strong ct6-like wing phenotype.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      ctMR2 has visible phenotype, suppressible by mod(mdg4)ul

      (Georgiev and Gerasimova, 1989)
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      ctMR2 has phenotype, suppressible by su(Hw)unspecified/su(Hw)unspecified

      (Hoover et al., 1992)

      ctMR2 has phenotype, suppressible by su(Hw)2

      (Georgiev and Gerasimova, 1989)

      ctMR2 has phenotype, suppressible by su(Hw)u1

      (Georgiev and Gerasimova, 1989)

      ctMR2 has phenotype, suppressible by su(Hw)u2

      (Georgiev and Gerasimova, 1989)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Phenotype is partially suppressed by mod(mdg4)ul at 25oC, and completely suppressed by mod(mdg4)ul at 18oC.

      (Georgiev and Gerasimova, 1989)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Highly unstable; mutates to either stable, unstable (most frequent, --> 10-4 mutations to ct), or superunstable (least frequent, --> around 50% ct mutants) alleles and to other ct alleles, which in turn may be unstable or superunstable. The gypsy sequence appears to be mobilized and transposed into other parts of the ct locus to produce new ct alleles or, when ct undergoes reversion, to other positions on the chromosomes where new mutants arise.

      Other types of transposing elements also appear to be mobilized in the ctMR2 unstable system.

      (Gerasimova et al., 1984)

      Unstable revertants are able to generate new ct derivatives, retain the gypsy LTR of ctMR2.

      (Mizrokhi et al., 1985)

      ctMR2 can revert or partially revert by excision of, or insertion of other elements (e.g. jockey or Hercules), into the gypsy insert responsible for ctMR2.

      (Leigh Brown et al., 1989)

      su(Hw) binding site in gypsy insertion in ct is full length.

      (Hoover et al., 1992)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ctMR2
      Name Synonyms
      Secondary FlyBase IDs
        References (13)