G2816443T
G1505C | Duox-PB; G1505C | Duox-PC
G1505C
2L_r6:2816443..2816443
The nucleotide change is correct and the amino acid change is reversed between Duox[Cy] and Duox[K] in Figure 1B.
(Amino acid change is revision of data in FBrf0230212).
Amino acid replacement: G1505C.
Nucleotide substitution: C?A.
lethal (with DuoxKG07745)
Cy1 is dominant in D.melanogaster/D.simulans hybrids.
Wings curled upward; rarely overlaps wild type at 25oC, but frequently overlaps at 19oC. Curvature caused by the unequal contraction of the upper and lower epithelia during the drying period following emergence from the pupa case (Waddington, 1940). Flightless but thoracic innervation normal (Chiarodo, Reing and Saranchak, 1971). Expression decreased by larval crowding, increased by increased temperature during pupal development (Nozawa, 1956). Classifiable in single dose in triploids. Usually homozygous lethal but may emerge as dwarf with more extreme wing character. Effective lethal phase late embryo-early larva (Kidwell, 1972). Cy is readily revertable by both EMS and irradiation. In addition some balanced Cy chromosomes pick up suppressors of Cy in stock. RK1A.
Complementation test based on lethal phenotype.
The curly winged mutant phenotype can be suppressed by exposure to fluorescent light.