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General Information
Symbol
Dmel\wgGla-1
Species
D. melanogaster
Name
FlyBase ID
FBal0005105
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Mutagen
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Insertion of a roo element 1.5kb upstream of the wg coding region.

Insertion components
roo{}wgGla-1
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

wgGla-1 mutant flies do not display any wing margin defects (nicks or notches).

Almost no photoreceptor cell structures are seen in the eye in heterozygotes. Most of the eye appears to consist of pigment cells and there is an excess of pigment granules. The overall distribution of pigment granules forms a faint regular pattern reminiscent of the arrangement of ommatidia in wild-type eyes. wgGla-1/wgrO216 animals develop into viable adults.

Abdomen of heterozygous female fails to expand with eggs.

Malpighian tubule colour: somewhat lighter than wild type; difficult to classify.

Abdomen of heterozygous female fails to distend with eggs; Eye reduced to one-fourth normal area and narrowed to a point ventrally; ommatidia coalesce into gleaming, smooth sheet. Eye colour: generally diluted but with some black patches.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Other
Statement
Reference
Phenotype Manifest In
Other
Statement
Reference

jigr12205, wg[+]/wgGla-1 has wing phenotype

Additional Comments
Genetic Interactions
Statement
Reference

The slightly reduced eye size and moderate wing margin nicking observed in the temperature-sensitive Nnd-1 homozygous adults at 18[o]C is enhanced by wgGla-1 heterozygosity: the ventral half of the adult eye is virtually completely lost and the wing notching phenotype is exacerbated too.

About 2/3 of wgGla-1/+;jigr12205/jigr12205 adult flies display a wing nicking phenotype (not observed in either of the single mutants alone), in rare cases very strong with extreme notches.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (1)
Stocks (138)
Notes on Origin
Discoverer

Induced on: In(2L)t. Associated with: In(2LR)Gla.

Associated with: In(2LR)Gla. The wgGla-1 mutation has been believed to be caused by one of the breakpoints of In(2LR)Gla, however evidence suggests that it is not associated with either breakpoint but is caused by the insertion of a roo element 1.5kb upstream of the wg coding region.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (9)