FB2025_01 , released February 20, 2025
Allele: Dmel\vgnw
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General Information
Symbol
Dmel\vgnw
Species
D. melanogaster
Name
no wing
FlyBase ID
FBal0017900
Feature type
allele
Associated gene
Dmel\vg
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Williams et al., 1990)
Mutagen
spontaneous
(Williams and Bell, 1988)
Progenitor genotype
Cytology

Polytene chromosomes normal.

(Williams et al., 1991)
Description

Deletion of introns 5, 6 and 7 and the 3' flanking sequences.

(Silber et al., 1993)

Exon deletion from position +13 to +16.

(Williams et al., 1991)

Deletion of a large exonic region of the vg locus.

(Williams et al., 1990)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2R:12,897,447..12,900,140 [+]
Linked to:
ClaI-ClaI restriction fragment
Comment:

Approximate location of the vgNW deletion, which removes exons 6-8 and the 3' flanking sequences.

(Williams et al., 1990)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      vgnw in transheterozygosity with Df(2R)Exel8056, vg13A, vgCL1, vgCZ, vgCL2C or vgDJ1R22 leads to wing defects, while vgnw in transheterozygosity with vgR5 does not.

      (Ahmad and Spens, 2019)

      Flies have tiny knobbed wings and halteres, erect postscutellar bristles and defects in the legs.

      (Abu-Issa and Cavicchi, 1996)

      Slightly resistant to aminopterin.

      (Silber et al., 1993)

      Tiny knobbed wings and halteres, erect postscutellars; low viability; female usually sterile; occasional wing nicks in vgnp/+; also shortened L2 vein in vgnp/+; small wing buds. RK2.

      (Lindsley and Zimm, 1992)

      Heterozygotes with vg83b27 have a less extreme reduction of wings and haltere structures.

      (Williams et al., 1991)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference

      vgCL2C/vgnw has visible | adult stage phenotype, enhanceable by Pc3/Pc[+]

      (Ahmad and Spens, 2019)

      vgCL2C/vgnw has visible | adult stage phenotype, enhanceable by Sceunspecified/Sce[+]

      (Ahmad and Spens, 2019)
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      vgCL2C/vgnw has wing phenotype, enhanceable by Pc3/Pc[+]

      (Ahmad and Spens, 2019)

      vgCL2C/vgnw has wing phenotype, enhanceable by Sceunspecified/Sce[+]

      (Ahmad and Spens, 2019)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Pc3 heterozygosity enhances the wing defects of vgCL2C/vgnw.

      vgR5/vgnw, Pc3/+ adults do not show wing notching.

      (Ahmad and Spens, 2019)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially complements

      vg83b27

      (Williams et al., 1990)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Secondary recessive lethal on the chromosome.

      (Rabinow and Birchler, 1990)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      vgNW
      (Silber et al., 1993, Williams et al., 1990, Reck, 1937)
      vgnw
      (Rubio-Ferrera et al., 2023, Ahmad and Spens, 2019)
      Name Synonyms
      no wing
      Secondary FlyBase IDs
        References (16)