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General Information
Symbol
Dmel\RpS2P
Species
D. melanogaster
Name
FlyBase ID
FBal0032757
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
transposable element insertion site
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

P{A92} insertion is located 28 nucleotides upstream of the 5' end of the cDNA.

Insertion components
P{A92}RpS2P
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

RpS2P/RpS2P mutants are viable and cause female sterility. RpS2P/RpS2P and RpS2P/RpS2PRW1 ovaries exhibit a "string of pearls" phenotype wherein all egg chambers arrest development at stages two or three, and also exhibit abnormalities in germline stem cell divisions, abnormal spectrosomes, and delayed egg chamber growth.

Semi-lethal. The survival rate of sopP homozygotes is 10-15% of normal. Homozygotes eclose at least 2 days later than their wild type sibs. Egg chambers in homozygous mutant ovaries appear to develop normally until approximately stage 5, but development does not continue beyond this point. Homozygotes also show a mutant bristle phenotype. Macrochaetae on the thorax and head are shorter and thinner and more brittle than those of heterozygous siblings or wild type flies.

Homozygous females arrest oogenesis at stage 5. Bristle phenotype in males and females.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhanced by
Statement
Reference

RpS2P/RpS2PRW1 has ovary | adult stage phenotype, enhanceable by Zfrp8[+]/Zfrp8SM206

Enhancer of
Statement
Reference

RpS2[+]/RpS2P is an enhancer of ovary | adult stage phenotype of Scer\GAL4nos.PU, Zfrp8GL00541

Additional Comments
Genetic Interactions
Statement
Reference

Zfrp8SM206/+ enhances the ovary phenotypes of RpS2P/RpS2PRW1 mutants.

RpS2P/+ enhances the ovary defects of flies expressing Zfrp8GL00541 under the control of Scer\GAL4nos.PU.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
Comments
Comments

Δ2-3 revertants have lost the P{A92} insertion.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (4)