RpS2P/RpS2P mutants are viable and cause female sterility. RpS2P/RpS2P and RpS2P/RpS2PRW1 ovaries exhibit a "string of pearls" phenotype wherein all egg chambers arrest development at stages two or three, and also exhibit abnormalities in germline stem cell divisions, abnormal spectrosomes, and delayed egg chamber growth.
Semi-lethal. The survival rate of sopP homozygotes is 10-15% of normal. Homozygotes eclose at least 2 days later than their wild type sibs. Egg chambers in homozygous mutant ovaries appear to develop normally until approximately stage 5, but development does not continue beyond this point. Homozygotes also show a mutant bristle phenotype. Macrochaetae on the thorax and head are shorter and thinner and more brittle than those of heterozygous siblings or wild type flies.
Homozygous females arrest oogenesis at stage 5. Bristle phenotype in males and females.