FB2025_01 , released February 20, 2025
Allele: Dmel\Ras85D+t12
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General Information
Symbol
Dmel\Ras85D+t12
Species
D. melanogaster
Name
FlyBase ID
FBal0033976
Feature type
allele
Associated gene
Dmel\Ras85D
Associated Insertion(s)
Carried in Construct
P{Ras85D+12}
Key Links
Genomic Maps

Transgenic product class
genomic_DNA
(Simon et al., 1991)
wild_type
(Simon et al., 1991)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Simon et al., 1991)
wild_type
(Simon et al., 1991)
Mutagen
in vitro construct
(Simon et al., 1991)
Progenitor genotype
Carried in construct
P{Ras85D+12}
Cytology
Description

Contained within a 12kb genomic XhoI-NotI fragment (NotI site from cloning vector polylinker). The XhoI site lies approximately 4.5kb 5' to the initiating codon of the Ras85D gene.

(Simon et al., 1991)
Allele components
Component
Use(s)
Regulatory region(s)
Ras85D
Encoded product / tool
Ras85D
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
3R:9,506,509..9,518,104 [-]
Linked to:
XhoI_END restriction fragment
Comment:

12kb rescue fragment initiates at a XhoI site 4.5kb upstream of Ras85D and extends to a point about 5kb downstream of Ras85D. The 3' restriction site used is a vector site. Therefore the 3' rescue fragment endpoint is approximate.

(Simon et al., 1991)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Ras85D+t12 rescues Ras85De2F/Ras85De1B

      (Simon et al., 1991)
      Comments

      Rescues the lethality of Ras85De2F/Ras85De1B flies.

      (Simon et al., 1991)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Ras85D+t12
      Name Synonyms
      Secondary FlyBase IDs
        References (2)