C618S | ed-PA; C618S | ed-PB; C618S | ed-PC
Amino acid replacement reported as reported as Cys to Ser, which could result from a nucleotide substitution in the first or second base of the codon. The mutation was annotated at the first base of the codon.
Expression of GripΔ1-3.Scer\UAS, under the control of Scer\GAL4twi.PG in a edslH8 background causes a mild lateral transverse muscle phenotype similar to that seen in edslH8 embryos without transgene expression. This is in contrast to the more severe phenotype seen when GripΔ1-3.Scer\UAS is expressed in a wild-type background.
Expression of EgfrDN.Scer\UAS.cBa under the control of Scer\GAL4ap-md544 partially suppresses the extra bristle phenotype seen in ed1X5/edslH8 flies. The number of macrochaetae/heminotum in animals expressing EgfrDN.Scer\UAS.cBa under the control of Scer\GAL4ap-md544 in a ed1X5/edslH8 background is - anterior+posterior notopleural: 2.15, presutural: 1.05, anterior supraalar: 0.80, posterior supraalar: 0, anterior postalar: 0.60, posterior postalar: 0, anterior+posterior dorsocentral: 1.30 and anterior+posterior scutellar: 2.25. N55e11/+ ; ed1X5/edslH8 adults show an almost complete absence of microchaetae on the notum. DlRevF10/+ increases the number of extra macrochaetae on the notum seen in ed1X5/edslH8 adults. H2/+ almost completely eliminates the extra macrochaetae seen on the notum of ed1X5/edslH8 animals, although the increased density of microchaetae seen in ed1X5/edslH8 flies is not reduced by H2/+. The low density of microchaetae on the notum seen in NMcd1/+ flies is not rescued by ed1X5/edslH8. The loss of macrochaetae on the notum seen in NAx-M1/+ flies is not rescued by ed1X5/edslH8.