Open Close
General Information
Symbol
Dmel\hidA22
Species
D. melanogaster
Name
FlyBase ID
FBal0045274
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Mutagen
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

C18173375T

Reported nucleotide change:

C910T

Amino acid change:

P171S | hid-PA; P171S | hid-PB

Reported amino acid change:

P170S

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: P170S.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Surviving transheterozygotes with Whid-A22 or Whid-A206 have an abnormal wing phenotype. The mutant wing appears opaque by comparison to wild type and occasionally contains trapped fluid. Transheterozygous males also possess improperly positioned terminalia. Some hemizygotes die before hatching and most of those that hatch possess properly formed cephalopharyngeal skeleton.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Mutant males can be ranked based on the severity of terminalia rotation: Df(3L)H99 > Whid-H109 > Whid-A22 > Whid-A206 > Whid-A329 > Whid-H89. The ranking is roughly similar to the one for the degree to which the alleles disrupt embryonic head development.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
References (9)