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General Information
Symbol
Cbeta\DTY28stop.chp
Species
L. Corynephage beta
Name
FlyBase ID
FBal0065303
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

A 4.5kb SalI-XbaI fragment from immediately upstream of the chp open reading frame drives expression of DT-A(Su+).

Allele components
Product class / Tool use(s)
Regulatory region(s)
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

In the absence of the amber suppressor (tRNA:Y1:22FaDtT.Su+) mild photoreceptor cell defects are observed: light transmission spots are blurred or missing. In the presence of tRNA:Y1:22FaDtT.Su+ the extent of photoreceptor cell defects is enhanced. Photoreceptor cell bodies and their associated rhabdomere specialisations are completely absent while the accessory ommatidial cells remain forming an empty honeycomb-like structure. Expression arrests photoreceptor cell development by 48 hours of pupal development. The larval photoreceptor nerve is also affected, ranging from being greatly reduced in diameter and broken at multiple sites to being ablated. Expression of a functional toxin does not reduce viability. Examination of the adult optic ganglia reveals the formation and maintenance of normal optic ganglia does not appear to require the continuous presence of intact larval or retinula photoreceptor cells.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
Cbeta\DT-AY28stop.chp
Cbeta\DTY28stop.chp
CbβDT-AY28stop.chp
Cbβ\DT-AY28stop.chp
Name Synonyms
Secondary FlyBase IDs
    References (2)