W145term | capt-PA; W504term | capt-PB; W145term | capt-PC
G to A nucleotide change at the second or third position of the Trp codon leads to a nonsense mutation. (exact site of mutation unspecified). Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.
eye disc & actin filament | somatic clone
neuron & eye disc | posterior | somatic clone
photoreceptor cell & eye disc | somatic clone
A captE636 heterozygous mutant background modifies the actin remodelling and subsequent basolateral invasion of epithelial cells seen in flies expressing CskGD9345 in a stripe of cells at the anterior/posterior boundary of the larval wing disc under the control of Scer\GAL4ptc-559.1.
captE636/+ mutant flies do not exhibit temperature-induced mobility defects.
Combination of Df(3R)Exel6184 in heterozygous state with a single copy of captE636 results in a significantly increased frequency of lamina plexus defects in the third instar larval brain and reduced rhabdomere length in the adult eye in the double heterozygotes.
Combination of DgO86 in heterozygous state with a single copy of captE636 does not significantly affect the frequency of lamina plexus defects in the third instar larvae but results in a significantly reduced rhabdomere length in the adults.
Central nervous system axons are seen to cross the midline in Abl2 captE636 double heterozygous embryos. Expression of captScer\UAS.cBa under the control of Scer\GAL4elav.PLu completely rescues the midline crossing defects seen in captE636 Abl2 double heterozygotes. Expression of captC.Scer\UAS under the control of Scer\GAL4elav.PLu partially rescues the midline crossing defects seen in captE636 Abl2 double heterozygotes.
Expression of captScer\UAS.cBa under the control of Scer\GAL4da.G32 rescues captE593/captE636 animals to viability, although the rescued adults sometimes show wing or eye defects. Expression of captC.Scer\UAS under the control of Scer\GAL4da.G32 rescues captE593/captE636 animals to viability and restores normal photoreceptor differentiation.