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General Information
Symbol
Dmel\ato2
Species
D. melanogaster
Name
FlyBase ID
FBal0117591
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Transposition insertion (of X chromosomal material) between 7 and 8kb upstream of the ato open reading frame, separating the eye-specific 5' enhancer element from the ato open reading frame.

Caused by aberration
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

ato1/ato2 antenna have a small number of coeloconic sensilla. The antennal lobes have normal glomeruli and the inter-antennal commissure is present. The elaboration of glial cell processes within the antennal lobe is normal.

ato1/ato2 flies have severely reduced eyes, which nevertheless contain ommatidia (approximately 200-300 in males, 5-15 in females). The ommatidia mostly contain fewer photoreceptors than wild type. The photoreceptor clusters are variably reduced, containing from 1-8 photoreceptors and any or all of the recruited photoreceptors can be affected. Photoreceptor axons navigate to the optic stalk poorly. This axon pathfinding defect is more severe in females. Those axons that reach the optic stalk are able to continue to their target sites within the optic lobe.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressed by
Statement
Reference

ato2 has phenotype, suppressible by ed4.12

Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
ato2
Name Synonyms
Secondary FlyBase IDs
    References (4)