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General Information
Symbol
Scer\GAL4neur-P72
Species
S. cerevisiae
Name
FlyBase ID
FBal0121958
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
neur-GAL4, neuralized-Gal4, neu-GAL4, neurP72-GAL4, neurP72GAL4, neuralizedP72-Gal4, neuP72
Allele class
Mutagen
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Cytology
Nature of the lesion
Statement
Reference

Created by P-element conversion of Ecol\lacZneur-A101.

Insertion components
P{GAL4}neurP72
Product class / Tool use(s)
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

Drives expression in sensory organ precursor cells.

neur, bib and fng reporter expression was observed during the formation of ball-and-socket joints in the leg. These drivers are expressed in different but overlapping cell populations in the developing joint. bib and neur are expressed in the deep region of the cavity, flanked by fng expression in cells projecting into the ridge and cells on the ventral side of the cavity. bib was expressed distal to neur, with an overlap of about two cells. Shortly after the onset of ball formation, bib-expressing cells are in contact with the ball cuticle. The expression of neur appears to overlap largely with bib-expressing cells and to extend dorsally to them. bib and neur expression domains are four to six cells wide along the anteroposterior axis. When the ball has fully grown, the apical surfaces of bib-expressing cells comes into contact with the ventral side of the ball, and then the apical surfaces further shifted distally, eventually contacting the newly formed lip. Consistently, the apices of the ventral portion of neur-expressing cells (co-expressing bib) relocate to the ventral side of the ball, and the apical surfaces of their dorsal subsets move with the edge of the extending socket, until covering the ventral part of the socket. Meanwhile, the dorsal fng-expressing cells expand their apical surfaces, and when the socket cuticle forms at the bottom of the cavity, they

cover a large dorsal portion of the socket cuticle. Live imaging was used to follow the bib- and neur-expressing cells.

 
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In

G1 phase & external sensory organ precursor cell IIa, with dapUAS.cLa

G1 phase & external sensory organ precursor cell IIb, with dapUAS.cLa

G1 phase & external sensory organ precursor cell IIIb, with CycEUAS.cLa

mesothoracic tergum & microchaeta, with Hsap\EZR1-280.UAS.GFP

sensory mother cell & filopodium, with DlUAS.cHa

sensory mother cell & filopodium, with Hsap\EZR1-280.UAS.GFP

Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference
Phenotype Manifest In
Suppressed by
Statement
Reference
Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Scer\GAL4neur-P72
neuralizedP72
Name Synonyms
Secondary FlyBase IDs
    References (58)