The mean nuclear diameter in interphase and the mean distance between segregating chromatids in anaphase is increased in mutant cells of neural ganglia compared to wild-type controls. Telophase chromatin reorganisation occurs prematurely in the mutant cells during mitosis, resulting in cells with an abnormally short distance between sister chromatid sets in telophase but not in anaphase.

Mutants show formation of chromosome bridges in anaphase and telophase, chromosome nondisjunction, and premature chromatin condensation after metaphase.

Mutants show defects in mitosis including polyploid metaphase plates, formation of chromatin bridges in both anaphase and telophase, formation of monopolar spindles in anaphase and the presence of polyploid cells. The frequency of anaphases and telophases is higher in the mutants than in wild type.