FB2025_01 , released February 20, 2025
Allele: Dmel\Axn8-66
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General Information
Symbol
Dmel\Axn8-66
Species
D. melanogaster
Name
FlyBase ID
FBal0138579
Feature type
allele
Associated gene
Dmel\Axn
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
chemical
(Penton et al., 2002)
Progenitor genotype
Cytology
Description

Amino acid replacement: R333K.

(Penton et al., 2002)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:30,032,091..30,032,091 [+]
Nucleotide change:

G30032091A

Amino acid change:

R333K | Axn-PA; R333K | Axn-PB; R333K | Axn-PC; R333K | Axn-PD; R333K | Axn-PF; R333K | Axn-PG

Reported amino acid change:

R333K

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Penton et al., 2002)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Axn8-66 is a suppressor of visible phenotype of Scer\GAL4GMR.PF, dshUAS.Tag:MYC

      (Penton et al., 2002)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Axn8-66 is a suppressor of eye phenotype of Scer\GAL4GMR.PF, dshUAS.Tag:MYC

      (Penton et al., 2002)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Axn8-66 does not modify wg or fz2 misexpression phenotypes.

      (Penton et al., 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Selected as: a suppressor of the eye phenotype caused by expression of dshScer\UAS.T:Hsap\MYC under the control of Scer\GAL4GMR.PF. Induced on: dshScer\UAS.T:Hsap\MYC. Separable from: dshScer\UAS.T:Hsap\MYC.

      (Penton et al., 2002)

      Induced on: a P{UAS-dsh.myc}3-8 chromosome.

      (Penton, 2006.5.11)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Axn8-66
      UAS-dsh M8-66
      (Penton et al., 2002)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)