FB2025_01 , released February 20, 2025
Allele: Scer\GAL4C587
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General Information
Symbol
Scer\GAL4C587
Species
S. cerevisiae
Name
FlyBase ID
FBal0150629
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
c587-Gal4, c587GAL4, c587, c587G4
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    distribution deduced from reporter (Gal4 UAS)
    Stage
    Tissue/Position (including subcellular localization)
    Reference
    Additional Information
    Statement
    Reference

    Drives expression during early gonadal development in the inner ovarian sheath cells, and in the early follicle cells, but not in cap cells. Drives expression in somatic cyst cells in the adult testis.

    During spermatogenesis, ScerGAL4C587 drives expression in all early somatic cells at the apical tip of the testis, including cyst progenitor cells (somatic cyst stem cells) and cyst cells.

    ScerGAL4C587 drives strong expression in escort cells and weak expression in follicle cell precursors in germarium region 2b

    Drives expression in escort stem cells, escort cells and early follicle cell progenitors in germarium region 1 and 2a and in early follicles in region 2b..

    Expression is observed during early gonadal development in the inner ovarian sheath cells, and in the early follicle cells, but not in the cap cells.

    Expression is observed in the somatic stem and somatic cyst cells of the adult testis.

    Expression is observed in the somatic (but not germline) cells of the developing ovary.

     
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference
    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Enhanced by
    NOT Enhanced by
    Suppressed by
    Statement
    Reference

    Scer\GAL4C587, dppUAS.cNa has neoplasia phenotype, suppressible | partially by pelo[+]/pelo1

    NOT suppressed by
    Statement
    Reference
    Enhancer of
    NOT Enhancer of
    Suppressor of
    Statement
    Reference
    NOT Suppressor of
    Statement
    Reference
    Phenotype Manifest In
    Enhanced by
    NOT Enhanced by
    Statement
    Reference
    Suppressed by
    Statement
    Reference

    Scer\GAL4C587, ph-pGD17398 has germarium phenotype, suppressible | partially by dpphr56/dpp[+]

    Scer\GAL4C587, smoJF02363 has germarium phenotype, suppressible by Stat92E[+]/Stat92E06346

    Scer\GAL4C587, smoJF02363 has spectrosome phenotype, suppressible by Stat92E[+]/Stat92E06346

    Scer\GAL4C587, ciGD1403 has germarium phenotype, suppressible by Stat92E[+]/Stat92E06346

    Scer\GAL4C587, ciGD1403 has spectrosome phenotype, suppressible by Stat92E[+]/Stat92E06346

    NOT suppressed by
    Statement
    Reference
    Enhancer of
    Statement
    Reference

    Scer\GAL4C587/hpoUAS.cWa is an enhancer of germarium | temperature conditional phenotype of hhAC2/hhts2

    NOT Enhancer of
    Statement
    Reference
    Suppressor of
    Statement
    Reference
    NOT Suppressor of
    Statement
    Reference

    Scer\GAL4C587/piwiUASp.cYa is a non-suppressor of ovary phenotype of ova4/ova1

    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (1)
    Notes on Origin
    Discoverer

    D. Drummond-Barbosa A. Spradling

    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    Scer\GAL4C587
    Name Synonyms
    Secondary FlyBase IDs
      References (143)