Q1569term | Itp-r83A-PA; Q1578term | Itp-r83A-PB; Q1569term | Itp-r83A-PC
Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.
Expression of Itp-r83AScer\UAS.cVa under the control of Scer\GAL4Ilp2.PR in Itp-r83Asv35/Itp-r83Aug3 mutant larvae significantly rescues reduced larval body size. Approximately half the surviving larvae can pupate and emerge as adults.
Expression of Itp-r83AScer\UAS.cVa under the control of Scer\GAL4Ddc.PL and Scer\GAL4Ilp2.PR in Itp-r83Asv35/Itp-r83Aug3 mutant larvae rescues body size and lethality. Survival is not improved beyond that observed with over-expression under the control of only Scer\GAL4Ddc.PL alone.