PGRP-LE112 adults infected with Erwinia carotovora carotovora by oral feeding exhibit an increase in the immune response (immune deficiency pathway activation) in proventriculus compared to controls.
PGRP-LE112 homozygous individuals exhibit a significantly increased bacterial load after infection with the non-pathogenic E. coli, as compared to equally infected controls.
Mutant flies show reduced survival after infection with Erwinia carotovora carotovora by septic injury compared to controls.
PGRP-LE112 flies show lower survival rates after L. monocytogenes infection compared to controls.
Hemolymph clots from PGRP-LE112 third instar larvae show normal melanization.