The spontaneous miniature release event (mepsp) amplitudes are significantly decreased in GluRIIASP16; ;Ephx652 double mutants compared to Ephx652 single mutants or wild-type. This double mutant phenotype is similar to the one observed in GluRIIASP16 single mutants.
The combination of ExnEY01953/+ and Ephx652/+ heterozygous mutations does not significantly change the GluRIIASP16 phenotype involving spontaneous miniature release event (mepsp) amplitudes, while it does partially suppress the GluRIIASP16 quantal content phenotype at the neuromuscular junction (NMJ).
Expression of EphrinScer\UAS.T:Hsap\MYC in the midline glia of embryos, driven by Scer\GAL4sim.PS, in an Ephx652 background does not cause the disruption of commissural axons seen when the transgene is expressed in wild-type embryos.
Flies that express EphrinScer\UAS.T:Hsap\MYC under the control of either Scer\GAL4OK107 or Scer\GAL4elav.PLu, in an Ephx652 background, show the same α'/α lobe defects as flies expressing the transgene in a wild-type background and as Ephx652 flies with no transgene.