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General Information
Symbol
Dmel\ab26
Species
D. melanogaster
Name
FlyBase ID
FBal0215331
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: R?C.

Nucleotide substitution: C?T.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

In ab26/Df(2L)FCK-20 embryos, the number of multidendritic sensory neurons is the same as in wild-type embryos but the number of dendritic branches is increased and the general pattern is disorganized.

ab26 dbd neuron clones exhibit ectopic dendritic processes. ab26 ddaE and ddaF neuron clones exhibit increased terminal dendritic branches, while other DA ab26 neurons in the dorsal cluster show normal dendritic morphology. ab26/+ third instar larvae show an increased number of ddaE dendritic ends compared to wild-type larvae, but this phenotype is less severe than in ab26 homozygous larvae. ab26/+ larvae also show an increased number of dendritic ends in vpda neurons. Detailed analysis of ab26/+ the dendritic trees of vpda neurons shows that the number of primary branches are not different from wild type, while there are far fewer tertiary and quarternary branches in comparison to wild type. In second instar ab26/+ larvae, there is only a 12% increase in the number of vpda dendritic ends, while there is a 39% increase in third instar larvae compared to controls.

In ab26/ab1 mutant larvae, ddaE neurons in A5 segments have 19% more dendritic branches that the wild type.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)