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General Information
Symbol
Dmel\sotiunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0221167
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygous mutants are viable and female fertile, but male sterile.

Mutant males do no have gross defects in testis organisation or spermatid elongation, but they have empty seminal vesicles, indicating defects in spermiogenesis. The waste bag that is normally formed from cytoplasm discarded at the distal end of spermatids as the individualisation complex moves along the developing spermatid is completely absent in mutant testes. The investment cones form normally above spermatid nuclei in mutant testes, however, the nuclei fail to remain tightly clustered and are displaced distally along the cyst. Although investment cones progress away from the nuclei in the mutant testis, investment cone coupling within individualisation complexes is lost and cones never progress the full length of the mutant spermatids.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
sotiunspecified
Name Synonyms
Secondary FlyBase IDs
    References (1)