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General Information
Symbol
Dmel\Rab21GD9042
Species
D. melanogaster
Name
FlyBase ID
FBal0277642
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Autolysosomes are normally absent in wild-type larvae under well-fed conditions but are rapidly induced with autophagy in response to starvation. Expression of Scer\GAL4Cg.PA>Rab21GD9042 blocks the appearance of autolysosomes in starved fat bodies.

Primary macrophages isolated from animals expressing Rab21GD9042 under the control of Scer\GAL4Cg.PA lack F-actin rich protrusions.

Expression under the control of Scer\GAL4Mef2.PR results in adult/pharate lethality.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Expression of SbfGD12081 enhances the loss of F-actin rich protrusions seen in macrophages isolated from animals expressing Rab21GD9042 under the control of Scer\GAL4Cg.PA.

Expression of Rab21GD9042 suppresses the excess F-actin rich protrusions seen in macrophages isolated from animals expressing SbfScer\UAS.T:Disc\RFP-mCherry under the control of Scer\GAL4Cg.PA.

Expression of Rab21GD9042 suppresses the excess F-actin rich protrusions seen in macrophages isolated from animals expressing mtmScer\UAS.T:Disc\RFP-mCherry under the control of Scer\GAL4Cg.PA.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Rab21GD9042
Name Synonyms
Secondary FlyBase IDs
    References (4)