FB2025_01 , released February 20, 2025
Allele: Dmel\ApcWT.GFP
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General Information
Symbol
Dmel\ApcWT.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0280780
Feature type
allele
Associated gene
Dmel\Apc
Associated Insertion(s)
Carried in Construct
P{Apc.GFP.WT}
Key Links
Transgenic product class
wild_type
(Roberts et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Roberts et al., 2012)
Mutagen
in vitro construct
(Roberts et al., 2012)
Progenitor genotype
Carried in construct
P{Apc.GFP.WT}
Cytology
Description

Encodes full-length, wild-type Apc which is tagged at the N-terminal end with GFP.

(Roberts et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
Apc
Encoded product / tool
Apc
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      ApcWT.GFP is a suppressor of lethal | embryonic stage phenotype of Apc2g10

      (Roberts et al., 2012)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      ApcWT.GFP is a suppressor of embryonic/larval cuticle phenotype of Apc2g10

      (Roberts et al., 2012)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      ApcWT.T:Avic\GFP strongly rescues the cuticle defects of embryos lacking both maternal and zygotic Apc2[+] function (homozygous Apc2g10 embryos derived from Apc2g10 females). The embryonic lethality is also partially rescued (31% lethality is seen) and viable adults are recovered.

      (Roberts et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ApcWT.GFP
      ApcWT.T:Avic\GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)