Open Close
General Information
Symbol
Dmel\trolUAS.RG
Species
D. melanogaster
Name
FlyBase ID
FBal0284928
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of the trol-RG isoform.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

The neural invasion phenotype (neural cells from the brain invade adjacent peripheral structures such as imaginal discs) observed in AdamTS-Arnwy1/AdamTS-Arnwy2 mutant third instar larvae is partially suppressed by Scer\GAL4ppl.PP-driven expression of trolUAS.RG.

Co-expression of trolScer\UAS.RG strongly enhances the commissural axon phenotype (failure to cross the midline) seen in embryos expressing Sema-1aScer\UAS.cYa under the control of Scer\GAL4P52 in a Sema-1ak13702 null background.

Co-expression of both trolScer\UAS.RG and Sema-1aScer\UAS.cYa under the control of Scer\GAL4tey-5053A results in significant RP5 neuron defasciculation defects at the final choice point between muscles 12 and 13. Targeting defects are also seen, resulting in premature bifurcations.

Co-expression of trolScer\UAS.RG significantly enhances the aberrant midline crossing phenotype seen in longitudinal tracts of embryos expressing plexAScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4elav.PU.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescues
Fails to rescue
Comments

Expression of trolScer\UAS.RG under the control of Scer\GAL4elav.PU significantly rescues the ISNb and SNa motor axon guidance defects seen in trolnull embryos. Expression under the control of Scer\GAL4repo.PU only very modestly rescues the motor axon defects, and expression under the control of Scer\GAL4twi.PU fails to rescue the motor axon defects.

Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
trolScer\UAS.RG
trolUAS.RG
Name Synonyms
Secondary FlyBase IDs
    References (2)