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General Information
Symbol
Scer\GAL4VT057358
Species
S. cerevisiae
Name
FlyBase ID
FBal0314034
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
VT57358-Gal4
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

A 2080 base pair fragment from the flanking non-coding or intronic region of Vsx1 is fused upstream of a Drosophila synthetic core promoter (DSCP) followed by sequence encoding a GAL4 driver.

Allele components
Product class / Tool use(s)
Associated Sequence Features
Expression Data
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Optogenetic activation (using Cnoc\ChR1Cs.IVS.20xUAS.Venus with 635 nm (red) light) of Scer\GAL4VT057358 neurons results in a significant increase in proboscis extension reflex (PER) in the absense of nutritional stimuli, compared to controls; PER in response to 100 mM sucrose presentation is unaffected.

Inhibition (using shi1.UAS at 30[o]C) of Scer\GAL4VT057358 neurons, or the combined set of Scer\GAL4GMR30A08 neurons and Scer\GAL4VT057358 neurons, does not affect PER in response to 100 mM sucrose presentation, compared to controls; inhibition of Scer\GAL4VT057358 neurons alone, but not the combined set of Scer\GAL4GMR30A08 neurons and Scer\GAL4VT057358 neurons, significantly increases PER in response to presentation of a sweet and bitter mixture, compared to controls.

Inhibition (using shi1.UAS at 30[o]C) of Scer\GAL4VT057358 neurons does not affect the reduction in PER response to presentation of 100 mM sucrose seen during quinine application to the proboscis, but sustained aversion after application is significantly reduced, compared to controls; this effect is also seen when silencing occurs only during or only after quinine application.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Scer\GAL4VT057358
Name Synonyms
Secondary FlyBase IDs
    References (3)