1191bp deletion that removes the translation start site and two-thirds of the coding region of Atg14.
Atg14Δ5.2/Atg14Δ5.2 is a suppressor | cell non-autonomous | partially of abnormal size | somatic clone | third instar larval stage phenotype of Ras85DV12.UAS, Scer\GAL4Act.PU, scrib673
Atg14EY14568/Atg14Δ5.2 is a suppressor of abnormal size | somatic clone | third instar larval stage phenotype of Atg13Δ81, Ras85DV12.UAS, Scer\GAL4Act.PU, scrib673
Atg14EY14568/Atg14Δ5.2 is a suppressor of neoplasia | somatic clone | third instar larval stage phenotype of Atg13Δ81, Ras85DV12.UAS, Scer\GAL4Act.PU, scrib673
Atg14Δ5.2/Atg14Δ5.2 is a suppressor | cell non-autonomous | partially of neoplasia | somatic clone | third instar larval stage phenotype of Ras85DV12.UAS, Scer\GAL4Act.PU, scrib673
Atg13Δ81, Atg13Δ81, Atg14Δ5.2, Atg14Δ5.2 is a suppressor | partially | somatic clone of abnormal size | somatic clone | third instar larval stage phenotype of Ras85DV12.UAS, Scer\GAL4Act.PU, scrib673
Atg13Δ81, Atg13Δ81, Atg14Δ5.2, Atg14Δ5.2 is a suppressor | partially | somatic clone of neoplasia | somatic clone | third instar larval stage phenotype of Ras85DV12.UAS, Scer\GAL4Act.PU, scrib673
Atg14Δ5.2/Atg14Δ5.2 is a suppressor | cell non-autonomous | partially of eye-antennal disc | somatic clone | third instar larval stage phenotype of Ras85DV12.UAS, Scer\GAL4Act.PU, scrib673
Atg13Δ81, Atg13Δ81, Atg14Δ5.2, Atg14Δ5.2 is a suppressor | partially | somatic clone of eye-antennal disc | somatic clone | third instar larval stage phenotype of Ras85DV12.UAS, Scer\GAL4Act.PU, scrib673
The size of scrib673-homozygous, Ras85DV12.Scer\UAS-expressing eye-antennal imaginal disc clone tumors is significantly suppressed either by Atg14Δ5.2 homozygosity in neighboring disc cells or by the combination of Atg13Δ81 homozygosity in clone cells plus Atg14Δ5.2 homozygosity in neighboring disc cells; these scrib673-homozygous, Ras85DV12.Scer\UAS-expressing tumors grow to significantly smaller sizes when grafted into the abdomen of Atg14Δ5.2/Atg14EY14568 transheterozygous adult hosts (but not if the hosts also possess one copy of Atg14+tCH322-175F03), as compared to control hosts.
Atg14Δ5.2 is rescued by Atg14+tCH322-175F03
The lethality of Atg14Δ5.2 homozygotes is rescued by the presence of one copy of Atg14+tCH322-175F03.