FlyBase Allele Report: Dmel\TAF1B[RNAi.UAS]

General Information

Symbol

Dmel\TAF1B^RNAi.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0335421

Feature type

allele

Associated gene

Dmel\TAF1B

Associated Insertion(s)

Carried in Construct

P{UAS-TAF1B.RNAi}

Key Links

Transgenic product class

RNAi_reagent

(Shalaby et al., 2017)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Shalaby et al., 2017)

Mutagen

in vitro construct

(Shalaby et al., 2017)

Progenitor genotype

Carried in construct

P{UAS-TAF1B.RNAi}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat (21nt CAGGACGATCCGACAGAAGAA sequence).

(Shalaby et al., 2017)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

TAF1B

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible | adult stage, with Scer\GAL4^ey.200.Exel

(Shalaby et al., 2017)

Phenotype Manifest In

eye, with Scer\GAL4^ey.200.Exel

(Shalaby et al., 2017)

Detailed Description

Statement

Reference

Expression of TAF1B^{dsRNA.Scer\UAS} under the control of Scer\GAL4^ey.200.Exel results in a rough eye phenotype in adult flies and frequent appearance of malformations resembling an antennal-like structure in the eyes.

(Shalaby et al., 2017)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has visible | adult stage phenotype, enhanceable by Utx[+]/Utx¹

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has visible | adult stage phenotype, enhanceable by NO66^UASp.Tag:HA, Scer\GAL4^ey.200.Exel

(Shalaby et al., 2017)

NOT Enhanced by

Statement

Reference

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has visible | adult stage phenotype, non-enhanceable by JHDM2[+]/Kdm3^KO

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has visible | adult stage phenotype, non-enhanceable by Jarid2[+]/Jarid2^KO

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has visible | adult stage phenotype, non-enhanceable by Df(3R)HSPBAP1-KO/+

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has visible | adult stage phenotype, non-enhanceable by JMJD4[+]/JMJD4^KO

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has visible | adult stage phenotype, non-enhanceable by Kdm4A[+]/Kdm4A^KO

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has visible | adult stage phenotype, non-enhanceable by JMJD5[+]/JMJD5^KO

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has visible | adult stage phenotype, non-enhanceable by Kdm4B[+]/Kdm4B^KO

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has visible | adult stage phenotype, non-enhanceable by lid[+]/Kdm5¹⁰⁴²⁴

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has visible | adult stage phenotype, non-enhanceable by Kdm2^KO/Kdm2[+]

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has visible | adult stage phenotype, non-enhanceable by PSR[+]/JMJD6^FM1

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has visible | adult stage phenotype, non-enhanceable by JMJD7[+]/JMJD7^KO

(Shalaby et al., 2017)

Suppressed by

Statement

Reference

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has visible | adult stage phenotype, suppressible | partially by NO66[+]/NO66^KO

(Shalaby et al., 2017)

NOT suppressed by

Statement

Reference

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has visible | adult stage phenotype, non-suppressible by lid[+]/Kdm5¹⁰⁴²⁴

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has visible | adult stage phenotype, non-suppressible by Kdm2^KO/Kdm2[+]

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has visible | adult stage phenotype, non-suppressible by Kdm4B[+]/Kdm4B^KO

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has visible | adult stage phenotype, non-suppressible by PSR[+]/JMJD6^FM1

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has visible | adult stage phenotype, non-suppressible by JMJD7[+]/JMJD7^KO

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has visible | adult stage phenotype, non-suppressible by JHDM2[+]/Kdm3^KO

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has visible | adult stage phenotype, non-suppressible by Jarid2[+]/Jarid2^KO

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has visible | adult stage phenotype, non-suppressible by Df(3R)HSPBAP1-KO/+

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has visible | adult stage phenotype, non-suppressible by JMJD4[+]/JMJD4^KO

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has visible | adult stage phenotype, non-suppressible by Kdm4A[+]/Kdm4A^KO

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has visible | adult stage phenotype, non-suppressible by JMJD5[+]/JMJD5^KO

(Shalaby et al., 2017)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has eye phenotype, enhanceable by Utx[+]/Utx¹

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has eye phenotype, enhanceable by NO66^UASp.Tag:HA, Scer\GAL4^ey.200.Exel

(Shalaby et al., 2017)

NOT Enhanced by

Statement

Reference

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has eye phenotype, non-enhanceable by JHDM2[+]/Kdm3^KO

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has eye phenotype, non-enhanceable by Jarid2[+]/Jarid2^KO

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has eye phenotype, non-enhanceable by Df(3R)HSPBAP1-KO/+

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has eye phenotype, non-enhanceable by JMJD4[+]/JMJD4^KO

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has eye phenotype, non-enhanceable by Kdm4A[+]/Kdm4A^KO

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has eye phenotype, non-enhanceable by JMJD5[+]/JMJD5^KO

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has eye phenotype, non-enhanceable by Kdm4B[+]/Kdm4B^KO

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has eye phenotype, non-enhanceable by lid[+]/Kdm5¹⁰⁴²⁴

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has eye phenotype, non-enhanceable by Kdm2^KO/Kdm2[+]

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has eye phenotype, non-enhanceable by PSR[+]/JMJD6^FM1

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has eye phenotype, non-enhanceable by JMJD7[+]/JMJD7^KO

(Shalaby et al., 2017)

Suppressed by

Statement

Reference

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has eye phenotype, suppressible | partially by NO66[+]/NO66^KO

(Shalaby et al., 2017)

NOT suppressed by

Statement

Reference

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has eye phenotype, non-suppressible by lid[+]/Kdm5¹⁰⁴²⁴

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has eye phenotype, non-suppressible by Kdm2^KO/Kdm2[+]

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has eye phenotype, non-suppressible by PSR[+]/JMJD6^FM1

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has eye phenotype, non-suppressible by JMJD7[+]/JMJD7^KO

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has eye phenotype, non-suppressible by JHDM2[+]/Kdm3^KO

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has eye phenotype, non-suppressible by Jarid2[+]/Jarid2^KO

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has eye phenotype, non-suppressible by Df(3R)HSPBAP1-KO/+

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has eye phenotype, non-suppressible by JMJD4[+]/JMJD4^KO

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has eye phenotype, non-suppressible by Kdm4A[+]/Kdm4A^KO

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has eye phenotype, non-suppressible by JMJD5[+]/JMJD5^KO

(Shalaby et al., 2017)

Scer\GAL4^ey.200.Exel, TAF1B^RNAi.UAS has eye phenotype, non-suppressible by Kdm4B[+]/Kdm4B^KO

(Shalaby et al., 2017)

Additional Comments

Genetic Interactions

Statement

Reference

The frequency of eye tissue to antenna-like malformed structures transformation in adult flies expressing TAF1B^{dsRNA.Scer\UAS} under the control of Scer\GAL4^ey.200.Exel is increased by co-expression of NO66^{Scer\UAS.P\T.T:Ivir\HA1} or by combination with a single copy of Utx¹, decreased by combination with NO66^KO and not significantly affected by combination with any of the following: lid¹⁰⁴²⁴, Kdm2^KO, PSR^FM1, JMJD7^KO, JHDM2^KO, Jarid2^KO, Df(3R)HSPBAP1-KO, JMJD4^KO, Kdm4A^KO, JMJD5^KO or Kdm4B^KO.

(Shalaby et al., 2017)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

TAF1B^RNAi.UAS

TAF1B^{dsRNA.Scer\UAS}

TAF1B^dsRNA.UAS

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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