FlyBase Allele Report: Dmel\vap[SH2mut32mut.UAS.Tag:MYC]

General Information

Symbol

Dmel\vap^{SH2mut32mut.UAS.Tag:MYC}

Species

D. melanogaster

Name

FlyBase ID

FBal0347592

Feature type

allele

Associated gene

Dmel\vap

Associated Insertion(s)

Carried in Construct

P{UAS-vap.SH2mut32mut.MYC}

Key Links

Transgenic product class

missense_variant

(Woodcock and Hughes, 2004)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

missense_variant

(Woodcock and Hughes, 2004)

Mutagen

in vitro construct

(Woodcock and Hughes, 2004, Feldmann et al., 1999)

Progenitor genotype

vap^UAS.Tag:MYC

(Woodcock and Hughes, 2004)

Carried in construct

P{UAS-vap.SH2mut32mut.MYC}

Cytology

Description

Mutation in both SH2 domains (amino acid replacements R110L and R278L).

(Woodcock and Hughes, 2004)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

vap

Tagged with

Tag:MYC

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Suppressor of

Statement

Reference

vap^{SH2mut32mut.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 is a non-suppressor of visible phenotype of Scer\GAL4^Bx-MS1096, htl::tor^4021.UAS

(Woodcock and Hughes, 2004, Feldmann et al., 1999)

Phenotype Manifest In

NOT Suppressor of

Statement

Reference

vap^{SH2mut32mut.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 is a non-suppressor of wing vein | ectopic phenotype of Scer\GAL4^Bx-MS1096, htl::tor^4021.UAS

(Woodcock and Hughes, 2004)

vap^{SH2mut32mut.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 is a non-suppressor of wing phenotype of Scer\GAL4^Bx-MS1096, htl::tor^4021.UAS

(Feldmann et al., 1999)

vap^{SH2mut32mut.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 is a non-suppressor of wing vein phenotype of Scer\GAL4^Bx-MS1096, htl::tor^4021.UAS

(Feldmann et al., 1999)

Additional Comments

Genetic Interactions

Statement

Reference

Does not suppress the wing phenotype caused by htl::tor^{4021.Scer\UAS} expressed under the control of Scer\GAL4^Bx-MS1096.

(Feldmann et al., 1999)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

RasGAP^SH2*32*

(Woodcock and Hughes, 2004)

RasGAP^{SH2mut.Scer\UAS}

vap^{SH2mut.Scer\UAS}

vap^SH2mut.UAS

vap^{SH2mut32mut.Scer\UAS.T:Hsap\MYC}

vap^{SH2mut32mut.UAS.Tag:MYC}

Name Synonyms

Secondary FlyBase IDs

FBal0097182
FBal0190418

References (3)

Report Sections

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