FB2025_01 , released February 20, 2025
Allele: Dmel\cystUASp.R
Open Close
General Information
Symbol
Dmel\cystUASp.R
Species
D. melanogaster
Name
FlyBase ID
FBal0356956
Feature type
allele
Associated gene
Dmel\cyst
Associated Insertion(s)
Carried in Construct
P{UASp-cyst.R}
Key Links
Transgenic product class
wild_type
(Silver et al., 2019)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Silver et al., 2019)
Mutagen
in vitro construct
(Silver et al., 2019)
Progenitor genotype
Carried in construct
P{UASp-cyst.R}
Cytology
Description

UASp regulatory sequences drive expression of the full-length cyst open reading frame. Silent mutations have been introduced at two distinct sites to confer resistance to RNAi mediated by the P{TRiP.HMS01750} transgene. The intron has also been removed.

(Silver et al., 2019)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
cyst
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Maternal expression of cystUASp.R under the control of Scer\GAL4VP16.mat.αTub67C leads to embryonic lethality, with the embryos displaying severe defects in head morphogenesis.

      (Silver et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Maternal co-expression of cystUASp.R and Rho1N19.UAS under the control of Scer\GAL4VP16.mat.αTub67C leads to embryonic cuticle defects that are similar to those induced by the expression of cystUASp.R alone, and milder than those induced by Rho1N19.UAS alone.

      (Silver et al., 2019)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      cystUASp.R
      Name Synonyms
      Secondary FlyBase IDs
        References (1)