Gene model reviewed during 5.47
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Acph-1 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Acph-1 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: Acph-1 CG7899
Chromosome homologies of Muller's element D (J chromosome in the Paleartic species and XR chromosome arm in Nearctic species) and of element E (O chromosome in the Paleartic species and 2 chromosome in Nearctic species) have been confirmed by single copy probes in the species of the obscura group and in D.melanogaster.
Gramoxone has no mutagenic effect on the genetic background of Acph-1.
No difference in allele fixed in lines selected over 700 generations for high (negative) and low (positive) geotaxis.
Acph-1 is encoded by a 2.1 kb transcript which is constitutively expressed throughout development with peaks in early embryonic and early pupal stages.
Structural gene for acid phosphatase 1, the major phosphatase in adults; responsible for approximately 90% of the low-pH nucleotidase activity throughout development. Serves as a reliable cytochemical marker in many tissues (FBrf0033183). Enzyme appears to be produced in nurse cells and follicular cells of ovary and transferred to oocyte through the ring canals and by pinocytosis, respectively (FBrf0029963); maternally produced enzyme persists to third instar; paternal gene function detectable in gels after 9-10 hr of embryonic development (FBrf0031356); and after 5 hr histochemically (FBrf0031363). Enzyme found in larvae, pupae and adults; levels increase during adult life (FBrf0027302).