actin, F-actin, E
Gene model reviewed during 5.54
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.56
Component of the Tip60 chromatin-remodeling complex which contains the catalytic subunit Tip60 and the subunits Domino, Tra1, Brd8, E(Pc), DMAP1, Pontin, Reptin, Ing3, Act87E, BAP55, Mrg15, MrgBP, Gas41 and YL-1.
Oxidation of Met-45 by Mical to form methionine sulfoxide promotes actin filament depolymerization. Methionine sulfoxide is produced stereospecifically, but it is not known whether the (S)-S-oxide or the (R)-S-oxide is produced.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Act87E using the Feature Mapper tool.
Act87E expression is observed in the adult dorsal vessel but not in the larval dorsal vessel.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Act87E in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: Act87E CG18290
In a sample of 79 genes with multiple introns, 33 showed significant heterogeneity in G+C content among introns of the same gene and significant positive correspondence between the intron and the third codon position G+C content within genes. These results are consistent with selection adding against preferred codons at the start of genes.
Age related changes in Act87E expression have been studied by Northern analysis.
Sequence analysis demonstrates insect muscle actins form a distinct family of closely related proteins significantly diverged from cytoplasmic actins.
Translation of actin RNA in early embryos injected with initiation factors has been studied.
No lethal mutations in Act87E gene were isolated during a molecular and genetic analysis of region including Act87E gene. Possible explanations include non-lethality of Act87E mutations or substitution of Act87E function by other actin-encoding genes in the genome.
Encodes actin found in larval muscle and adult cephalic and abdominal muscle (FBrf0038990).