FB2026_03 , released September 17, 2026
Gene: Dmel\tj
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General Information
Symbol
Dmel\tj
Species
D. melanogaster
Name
traffic jam
Annotation Symbol
CG10034
Feature Type
protein_coding_gene
FlyBase ID
FBgn0000964
Gene Model Status
Current
Stock Availability
21 publicly available
Gene Summary
traffic jam (tj) encodes a Maf transcription factor that functions as regulator of multiple gonad morphogenesis processes including collective cell migration during oogenesis and stem cell specification downstream of Notch signaling during spermatogenesis. [Date last reviewed: 2019-03-14] (FlyBase Gene Snapshot)
All Summaries
Also Known As

maf1

Key Links
Genomic Location
Cytogenetic map
37E3-37E3
Sequence location
Recombination map
2-54
RefSeq locus
NT_033779 REGION:19464267..19467758
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (17 terms)
Molecular Function (4 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (4 terms)
CV Term
Evidence
References
enables DNA binding
inferred from electronic annotation with InterPro:IPR004826, InterPro:IPR008917
(InterPro Project Members, 2004-)
enables DNA-binding transcription factor activity, RNA polymerase II-specific
inferred from biological aspect of ancestor with PANTHER:PTN002561999
(GO Reference Genome Project, 2011-)
enables DNA-binding transcription factor activity
inferred from electronic annotation with InterPro:IPR024874
(InterPro Project Members, 2004-)
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding
inferred from biological aspect of ancestor with PANTHER:PTN002561999
(GO Reference Genome Project, 2011-)
Biological Process (11 terms)
Terms Based on Experimental Evidence (9 terms)
CV Term
Evidence
References
involved_in border follicle cell migration
inferred from mutant phenotype
(Gunawan et al., 2013)
involved_in cell fate specification
inferred from mutant phenotype
(Panchal et al., 2017)
involved_in female gonad development
inferred from high throughput mutant phenotype
(Schupbach and Wieschaus, 1991)
involved_in gene expression
inferred from mutant phenotype
(Saito et al., 2009)
involved_in germ cell development
inferred from mutant phenotype
(Panchal et al., 2017)
involved_in gonad morphogenesis
inferred from mutant phenotype
(Panchal et al., 2017, Li et al., 2003)
involved_in male gonad development
inferred from high throughput mutant phenotype
(Schupbach and Wieschaus, 1991)
involved_in positive regulation of gene expression
inferred from mutant phenotype
(Konstantinides et al., 2018)
involved_in positive regulation of transcription by RNA polymerase II
inferred from mutant phenotype
(Gunawan et al., 2013)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
involved_in regulation of DNA-templated transcription
inferred from electronic annotation with InterPro:IPR004826, InterPro:IPR008917, InterPro:IPR024874
(InterPro Project Members, 2004-)
involved_in regulation of transcription by RNA polymerase II
inferred from biological aspect of ancestor with PANTHER:PTN002561999
(GO Reference Genome Project, 2011-)
Cellular Component (2 terms)
Terms Based on Experimental Evidence (2 terms)
CV Term
Evidence
References
located_in cytosol
inferred from direct assay
(Baker et al., 2023)
located_in nucleus
inferred from direct assay
(Baker et al., 2023, Gunawan et al., 2013, Jemc et al., 2012, Li et al., 2003)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
is_active_in nucleus
inferred from biological aspect of ancestor with PANTHER:PTN002561999
(GO Reference Genome Project, 2011-)
Gene Group / Complex (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Snapshot
traffic jam (tj) encodes a Maf transcription factor that functions as regulator of multiple gonad morphogenesis processes including collective cell migration during oogenesis and stem cell specification downstream of Notch signaling during spermatogenesis. [Date last reviewed: 2019-03-14]
Gene Group / Complex (FlyBase)
BASIC LEUCINE ZIPPER TRANSCRIPTION FACTORS -
The basic leucine zipper (bZIP) transcription factors are sequence-specific DNA-binding proteins that regulate transcription. They are characterized by a 60-80 amino acid bZIP domain: a basic DNA binding domain followed by a leucine zipper dimerization domain. (Adapted from FBrf0152056).
Summary (Interactive Fly)

orthologue of a large Maf transcription factor in mammals - gonad development - somatic gonadal cells - follicle cells - germline- soma interactions - a transcriptional target of Hh signaling controlling cell-cell adhesion by negative regulation of E-cadherin expression

Gene Model and Products
Number of Transcripts
2
Number of Unique Polypeptides
2

Please see the JBrowse view of Dmel\tj for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry M9PG80)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Stop-codon suppression (UGA) postulated; FBrf0216884.

Gene model reviewed during 5.44

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
tj-RB
FBtr0301669
NM_136125
3492
511
tj-RC
FBtr0329891
NM_001273653
3492
555
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
tj-PB
FBpp0290883
54.3
511
7.43
Q9VIW0
NP_609969
AAF53804
tj-PC
FBpp0302925
59.1
555
7.69
M9PG80
NP_001260582
AGB93117
Polypeptides with Identical Sequences

None of the polypeptides share 100% sequence identity.

Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\tj using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.84

Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 12 -- 17
gonad

Comment: in somatic cells

(Li et al., 2003)
embryonic stage 14
larval central nervous system | restricted
(Li et al., 2003)
Additional Descriptive Data

tj ies expressed in somatic gonadal cells that are in direct contact with germline cells throughout development.

(Li et al., 2003)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 12 -- 17
gonad

Comment: in somatic cells

(Li et al., 2003)
embryonic stage 13 | male -- first instar larval stage | male
somatic cell of testis
(Okegbe and DiNardo, 2011)
larval stage -- adult stage
gonad

Comment: in somatic cells

(Li et al., 2003)
oogenesis stage S8 -- S10 & adult stage | female
follicle cell
(Gunawan et al., 2013)
polar follicle cell
(Gunawan et al., 2013)
adult stage | femaleoogenesis stage S8 -- S10
border follicle cell
(Gunawan et al., 2013)
spermatogenesis
hub cell
(Voog et al., 2008)
cyst cell of testis
(Voog et al., 2008)
somatic stem cell
(Voog et al., 2008)
Additional Descriptive Data

Within the border cell cluster, tj is expressed more strongly in the polar follicle cells, compared to the rosette cells (non-polar border cells).

(Gunawan et al., 2013)

tj protein is strongly expressed in cyst cell nuclei and weakly expressed in hub cells.

(Voog et al., 2008)

tj ies expressed in somatic gonadal cells that are in direct contact with germline cells throughout development.

(Li et al., 2003)
Marker for
 
cyst cell of testis
(Voog et al., 2008)
gonadal sheath proper primordium
(Jemc et al., 2012)
somatic cell of ovariole
(Nystul and Spradling, 2010, Parma et al., 2007)
Subcellular Localization
CV Term
Evidence
References
located_in cytosol
inferred from direct assay
(Baker et al., 2023)
located_in nucleus
inferred from direct assay
(Baker et al., 2023, Gunawan et al., 2013, Jemc et al., 2012, Li et al., 2003)
Expression Deduced from Reporters
Reporter: P{GawB}tjNP1624
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage & larval stage
neuron of larval ventral nerve cord
(Babski et al., 2019)
embryonic stage 13 -- third instar larval stage
larval DO1 motor neuron
(Babski et al., 2019)
larval DO2 motor neuron
(Babski et al., 2019)
larval LL1 motor neuron
(Babski et al., 2019)
embryonic stage 16 -- third instar larval stage
larval DO5 motor neuron
(Babski et al., 2019)
neuron | subset of larval intersegmental nerve branch ISNd of A1-7
(Babski et al., 2019)
third instar larval stage
larval central brain
(Olson et al., 2019)
adult stage
adult brain | restricted
(Ameku et al., 2018)
adult ventral nerve cord | restricted
(Ameku et al., 2018)
spermatogenesis & adult stage | male
cyst progenitor cell
(Fairchild et al., 2016, Chen et al., 2013)
adult stage | male & spermatogenesis
cyst cell of testis
(Chen et al., 2013)
hub cell | faint
(Fairchild et al., 2016)
secondary spermatogonium
(Fairchild et al., 2016)
oogenesis
somatic cell of ovariole
(Olivieri et al., 2012)
spermatogenesis
cyst cell of testis
(Chiang et al., 2017)
Reporter: P{GMR40H07-lexA}
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage | male
cyst progenitor cell
(Inaba et al., 2015)
Reporter: P{tj-GAL4.U}
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage | female & oogenesis
follicle stem cell
(Sahai-Hernandez and Nystul, 2013)
follicle cell
(Sahai-Hernandez and Nystul, 2013)
oogenesis stage S10
somatic cell of ovariole
(Ruppert et al., 2017)
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\tj in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 20 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 13 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of tj
Transgenic constructs containing regulatory region of tj
Aberrations (Deficiencies and Duplications) ( 10 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4Mef2.PR
viable, with Scer\GAL4pnr-MD237
viable, with Scer\GAL4tin.CΔ4
viable | recessive
Sterility
Allele
female sterile
male sterile
semi-fertile (with tj39)
semi-fertile (with tjPL3)
sterile
Other Phenotypes
Allele
abnormal cell shape | larval stage | somatic clone, with Scer\GAL4Act5C.PU
abnormal developmental rate, with Df(2L)E55, Scer\GAL4slbo.2.6
abnormal developmental rate, with Scer\GAL4slbo.2.6
abnormal developmental rate (with tj39)
abnormal developmental rate (with tjPL3)
abnormal size | adult stage
abnormal size | adult stage, with Scer\GAL4NP1624
abnormal size | adult stage (with tj39)
abnormal size | adult stage (with tjPL3)
decreased cell number | adult stage
decreased cell number | adult stage (with tj39)
decreased cell number | adult stage (with tjPL3)
visible, with Scer\GAL4Bx-MS1096
visible | male limited, with Scer\GAL4Bx-MS1096
Phenotype manifest in
Allele
border follicle cell, with Df(2L)E55, Scer\GAL4slbo.2.6
border follicle cell, with Scer\GAL4slbo.2.6
border follicle cell (with tj39)
border follicle cell (with tjPL3)
border follicle cell | somatic clone, with Scer\GAL4Act5C.PP
egg chamber
female germline stem cell | adult stage
female germline stem cell | adult stage (with tj39)
female germline stem cell | adult stage (with tjPL3)
female germline stem cell | P-stage
germarium | adult stage
germarium | adult stage (with tj39)
germarium | adult stage (with tjPL3)
germarium | adult stage | somatic clone
germarium cap cell | adult stage
germarium cap cell | adult stage, with Scer\GAL4NP1624
germarium cap cell | adult stage (with tj39)
germarium cap cell | adult stage (with tjPL3)
germarium cap cell | adult stage (with tjz4735)
germarium cap cell | adult stage | cell autonomous | somatic clone
germarium cap cell | prepupal stage
germarium cap cell | prepupal stage (with tjPL3)
germarium cap cell | prepupal stage (with tjz4735)
ovarian sheath | ectopic
ovary
ovary | adult stage
ovary | adult stage, with Scer\GAL4NP1624
ovary | adult stage (with tj39)
ovary | adult stage (with tjPL3)
terminal filament | adult stage
terminal filament | adult stage, with Scer\GAL4NP1624
terminal filament | adult stage (with tj39)
terminal filament | adult stage (with tjPL3)
terminal filament | adult stage (with tjz4735)
terminal filament | adult stage | somatic clone
terminal filament | ectopic
terminal filament | larval stage | somatic clone, with Scer\GAL4Act5C.PU
terminal filament | prepupal stage
terminal filament | prepupal stage (with tjPL3)
terminal filament | prepupal stage (with tjz4735)
testis
testis & fusome
wing, with Scer\GAL4Bx-MS1096
wing | male limited, with Scer\GAL4Bx-MS1096
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (12)
Hsap\MAFB
11 of 14
Yes
Yes
Hsap\MAFA
10 of 14
No
Yes
Hsap\MAF
10 of 14
No
Yes
Hsap\NRL
9 of 14
No
Yes
Hsap\MAFF
4 of 14
No
No
1  
Hsap\MAFG
4 of 14
No
No
1  
Hsap\MAFK
4 of 14
No
No
1  
Hsap\HYDIN
1 of 14
No
No
Hsap\NFE2
1 of 14
No
No
1  
Hsap\NFE2L1
1 of 14
No
No
Hsap\NFE2L2
1 of 14
No
No
Hsap\NFE2L3
1 of 14
No
No
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (10)
Rnor\Mafb
11 of 14
Yes
Yes
Rnor\Maf
10 of 14
No
Yes
Rnor\Nrl
10 of 14
No
Yes
Rnor\Mafa
9 of 14
No
Yes
Rnor\Maff
4 of 14
No
No
Rnor\Mafg
4 of 14
No
No
Rnor\Mafk
4 of 14
No
No
Rnor\Nfe2l1
1 of 14
No
No
Rnor\Nfe2l3
1 of 14
No
No
Rnor\Nfe2
1 of 14
No
No
Mus musculus (laboratory mouse) (10)
Mmus\Mafb
10 of 14
Yes
Yes
Mmus\Maf
10 of 14
Yes
Yes
Mmus\Mafa
9 of 14
No
Yes
Mmus\Nrl
9 of 14
No
Yes
Mmus\Mafg
5 of 14
No
No
Mmus\Mafk
5 of 14
No
No
Mmus\Maff
4 of 14
No
No
Mmus\Nfe2l3
1 of 14
No
No
Mmus\Nfe2
1 of 14
No
No
Mmus\Spertl
1 of 14
No
Yes
Xenopus tropicalis (Western clawed frog) (13)
Xtro\mafb
9 of 13
Yes
Yes
Xtro\mafa
7 of 13
No
Yes
Xtro\maf
7 of 13
No
Yes
Xtro\nrl
7 of 13
No
Yes
Xtro\maff
2 of 13
No
No
Xtro\mafk
2 of 13
No
No
Xtro\mafg
1 of 13
No
Yes
Xtro\nfe2l1
1 of 13
No
No
Xtro\nfe2l3
1 of 13
No
No
Xtro\nfe2
1 of 13
No
No
Xtro\rab35
1 of 13
No
No
Xtro\tspan6
1 of 13
No
No
Xtro\xbp1
1 of 13
No
No
Danio rerio (Zebrafish) (15)
Drer\mafba
10 of 14
Yes
Yes
Drer\mafbb
10 of 14
Yes
Yes
Drer\mafb
10 of 14
Yes
Yes
Drer\mafaa
9 of 14
No
Yes
Drer\mafa
9 of 14
No
Yes
Drer\nrl
8 of 14
No
Yes
Drer\maff
4 of 14
No
No
Drer\mafga
3 of 14
No
No
Drer\mafgb
3 of 14
No
No
Drer\mafk
3 of 14
No
No
Drer\atf6b
1 of 14
No
No
Drer\bach1a
1 of 14
No
Yes
Drer\nfe2
1 of 14
No
No
Drer\nfe2l1b
1 of 14
No
No
Drer\nfe2l2a
1 of 14
No
No
Caenorhabditis elegans (Nematode, roundworm) (2)
Cele\maf-1
7 of 14
Yes
Yes
Cele\mrck-1
1 of 14
No
No
Anopheles gambiae (African malaria mosquito) (4)
Agam\AgaP_AGAP010030
11 of 12
Yes
Yes
Agam\AgaP_AGAP010405
3 of 12
No
No
Agam\AgaP_AGAP005300
1 of 12
No
No
Agam\AgaP_AGAP010623
1 of 12
No
No
Arabidopsis thaliana (thale-cress) (0)
Saccharomyces cerevisiae (Brewer's yeast) (0)
Schizosaccharomyces pombe (Fission yeast) (0)
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:tj. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (3)
maf-S
6 of 13
cnc
1 of 13
kay
1 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 6 )
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    MAFB; MAF bZIP transcription factor B
    11 of 14
    608968
    MAFA; MAF bZIP transcription factor A
    10 of 14
    610303
      MAF; MAF bZIP transcription factor
      10 of 14
      177075
      NRL; neural retina leucine zipper
      9 of 14
      162080
      MAFF; MAF bZIP transcription factor F
      4 of 14
      604877
           
          MAFG; MAF bZIP transcription factor G
          4 of 14
          602020
               
              MAFK; MAF bZIP transcription factor K
              4 of 14
              600197
                   
                  Functional Complementation Data
                  Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
                  Interactions
                  Summary of Physical Interactions
                  Summary of Genetic Interactions
                  Interaction Browsers
                  View in FlyBase Interactions Browser   View in MIST tool (external link)
                  Please look at the allele data for full details of the genetic interactions
                  Starting gene(s)
                  Interaction type
                  Interacting gene(s)
                  Reference
                  tj
                  suppressible
                  shg
                  (Gunawan et al., 2013)
                  tj
                  suppressible
                  slbo
                  (Gunawan et al., 2013)
                  Starting gene(s)
                  Interaction type
                  Interacting gene(s)
                  Reference
                  slbo
                  enhanceable
                  tj
                  (Gunawan et al., 2013)
                  External Data
                  Linkouts
                  DroID - A comprehensive database of gene and protein interactions.
                  MIST (genetic) - An integrated Molecular Interaction Database
                  MIST (protein-protein) - An integrated Molecular Interaction Database
                  Pathways
                  Signaling Pathways (FlyBase)
                  Metabolic Pathways
                  FlyBase
                  External Links
                  External Data
                  Linkouts
                  Class of Gene
                  Genomic Location and Detailed Mapping Data
                  Chromosome (arm)
                  2L
                  Recombination map
                  2-54
                  Cytogenetic map
                  37E3-37E3
                  Sequence location
                  FlyBase Computed Cytological Location
                  Cytogenetic map
                  Evidence for location
                  37E3-37E3
                  Limits computationally determined from genome sequence between P{EP}dntEP2158 and P{EP}EP623&P{PZ}spi01068
                  Experimentally Determined Cytological Location
                  Cytogenetic map
                  Notes
                  References
                  Mapped between the proximal breakpoint of deletion "Df(2L)VA20" and the distal breakpoint of deletion "Df(2L)pr26".
                  (Li et al., 2003)
                  37E1-37E1
                  (Li et al., 2003)
                  Experimentally Determined Recombination Data
                  Location

                  2-54

                  (FlyBase, 2016)

                  2-53.7

                  (Comeron et al., 2012)
                  Left of (cM)
                  Right of (cM)
                  Notes
                  Stocks and Reagents
                  Stocks (21)
                  Genomic Clones (25)
                  cDNA Clones (14)
                   

                  Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

                  cDNA clones, fully sequenced
                  BDGP DGC clones
                    Other clones
                    Drosophila Genomics Resource Center cDNA clones

                    For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

                    cDNA Clones, End Sequenced (ESTs)
                    BDGP DGC clones
                    Other clones
                    RNAi and Array Information
                    Linkouts
                    DRSC - Results frm RNAi screens
                    Antibody Information
                    Laboratory Generated Antibodies
                     

                    polyclonal

                    (Gunawan et al., 2013, Jemc et al., 2012, Morris and Spradling, 2011, Li et al., 2003)
                    Commercially Available Antibodies
                     
                    Cell Line Information
                    Publicly Available Cell Lines
                     
                      Other Stable Cell Lines
                       

                      • New stable cell line derived from OSC : A stable OSC reporter line was generated carrying the tj enhancer driven GFP_P2A-blasticidin-resistance harboring ten intronic boxB sites and 14 upstream UAS sites; Addgene 128010.

                        (Batki et al., 2019)
                      Other Comments

                      Identification: PCR product, using primers for conserved sequences among vertebrate maf genes.

                      (Mohler et al., 1997)

                      Mutants affect normal oogenesis.

                      (Digilio et al., 1996)

                      The tj locus affects early oogenesis: mutations cause the production of few, defective germ cells.

                      (Schupbach and Wieschaus, 1991)
                      Relationship to Other Genes
                      Source for database merge of

                      Source for merge of: tj maf1

                      (Mohler, 2006.5.4)

                      Source for merge of: tj CG10034

                      (FlyBase, 1996-)
                      Additional comments

                      Source for merge of tj CG10034 was sequence comparison ( date:030729 ).

                      (FlyBase, 1996-)
                      Nomenclature History
                      Source for database identify of

                      Source for identity of: tj CG10034

                      (Li et al., 2003)
                      Nomenclature comments
                      Etymology
                      Synonyms and Secondary IDs (18)
                      Reported As
                      Symbol Synonym
                      CG10034
                      (National Institute of Genetics Fly Stocks, 2022-, Reinke et al., 2013, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Perkins et al., 2009.1.15, Giot et al., 2003, Kawashima et al., 2003, Li et al., 2003, Fassler et al., 2002)
                      DM13
                      (Reinke et al., 2013)
                      Dmaf
                      (Kawashima et al., 2003)
                      PL3
                      (Digilio et al., 1996)
                      TJ
                      (Sênos Demarco et al., 2020, Sreejith et al., 2019, Tamirisa et al., 2018, Fidler et al., 2014, Voog et al., 2014, Chen et al., 2013, König and Shcherbata, 2013, Hongay and Orr-Weaver, 2011, Zamparini et al., 2011, Voog et al., 2008, Yogev et al., 2008)
                      Tj
                      (Rivera et al., 2025, Clémot et al., 2024, Kotov et al., 2024, Sreejith and Kim, 2023, Adashev et al., 2022, Ray et al., 2022, Johnson and Leatherman, 2021, Reilein et al., 2021, Akishina et al., 2018, Tang et al., 2017, Friedrich et al., 2016, Kotov et al., 2016, Monahan and Starz-Gaiano, 2016, Peng et al., 2016, Gonzalez et al., 2015, Smendziuk et al., 2015, Hayashi et al., 2014, Maimon et al., 2014, Tripathy et al., 2014, Pancratov et al., 2013, Singh et al., 2013, Morillo Prado et al., 2012, Morris and Spradling, 2012, Zoller and Schulz, 2012, Morris and Spradling, 2011, Okegbe and DiNardo, 2011, Xu et al., 2011, Flaherty et al., 2010, Leatherman and Dinardo, 2010, Singh et al., 2010, Leatherman and DiNardo, 2008, Wang et al., 2006)
                      fs(2)eo-B
                      fs(2)eo2
                      fs(2)eoPL3
                      maf-L
                      (Mohler, 2006.5.4)
                      maf1
                      (Mohler et al., 1997)
                      tj
                      (Hu et al., 2026, Simon et al., 2026, Alizada et al., 2025, Mukherjee et al., 2025, Xu et al., 2025, Collins et al., 2024, Drewell et al., 2024, Zhang et al., 2024, Delbare et al., 2023, Santos et al., 2023, Karki et al., 2022, National Institute of Genetics Fly Stocks, 2022-, Gowda et al., 2021, Simon and Konstantinides, 2021, Slaidina et al., 2021, Wolfe et al., 2021, Delbare et al., 2020, Meyer-Nava et al., 2020, Rust et al., 2020, Slaidina et al., 2020, Babski et al., 2019, Hirakata and Siomi, 2019, Ishizu et al., 2019, Lehmann et al., 2019, Li et al., 2019, Munafò et al., 2019, Shokri et al., 2019, Story et al., 2019, Cho et al., 2018, Gene Disruption Project members, 2018-, Kang et al., 2018, Lai et al., 2017, Panchal et al., 2017, Transgenic RNAi Project members, 2017-, Sarov et al., 2016, Ishizu et al., 2015, Mugat et al., 2015, Schertel et al., 2015, Shlyueva et al., 2014, Gunawan et al., 2013, Jin et al., 2013, Jukam et al., 2013, Jukam et al., 2013, Ohtani et al., 2013, Vaque et al., 2013, Japanese National Institute of Genetics, 2012.5.21, Jemc et al., 2012, Muerdter et al., 2012, Preall et al., 2012, Gancz et al., 2011, Jungreis et al., 2011, Toku et al., 2011, Weyers et al., 2011, Olivieri et al., 2010, Rigoutsos, 2010, Saito et al., 2010, Robine et al., 2009, Saito et al., 2009, Christensen and Cook, 2007.5.8, Hempel and Oliver, 2007, Parma et al., 2007, Hoskins et al., 2005, Li et al., 2003)
                      Name Synonyms
                      Traffic Jam
                      (Tamirisa et al., 2018, Saadin and Starz-Gaiano, 2016, Gonzalez et al., 2015, Reilly et al., 2015, Whitworth et al., 2012, Baxley et al., 2011, Eliazer et al., 2011, Hongay and Orr-Weaver, 2011, Voog et al., 2008, Parma et al., 2007, Tanentzapf et al., 2007, Gilboa and Lehmann, 2006)
                      Traffic jam
                      (Darricarrère et al., 2013, Gunawan et al., 2013, König and Shcherbata, 2013, Green and Extavour, 2012, Morris and Spradling, 2011, Okegbe and DiNardo, 2011, Xu et al., 2011, Olivieri et al., 2010, Hempel and Oliver, 2007, Gilboa and Lehmann, 2006)
                      Traffic-Jam
                      (Morillo Prado et al., 2012, Yogev et al., 2008)
                      Traffic-jam
                      (Xu et al., 2011)
                      female sterile(2)eo2
                      traffic jam
                      (Sato et al., 2015, Basquin et al., 2014, Jukam et al., 2013, Ohtani et al., 2013, Jemc et al., 2012, Muerdter et al., 2012, Olivieri et al., 2012, Reich and Papoulas, 2012, Zamparini et al., 2011, Leatherman and Dinardo, 2010, Rigoutsos, 2010, Robine et al., 2009, Saito et al., 2009, Leatherman and DiNardo, 2008, Levine et al., 2007, Li et al., 2003)
                      Secondary FlyBase IDs
                      • FBgn0020276
                      • FBgn0032786
                      Datasets (0)
                      Study focus (0)
                      Experimental Role
                      Project
                      Project Type
                      Title
                      Study result (0)
                      Result
                      Result Type
                      Title
                      External Crossreferences and Linkouts ( 39 )
                      Sequence Crossreferences
                      NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
                      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
                      GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
                      RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
                      UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
                      UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
                      Other crossreferences
                      AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
                      BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
                      DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
                      EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
                      FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
                      FlyMine - An integrated database for Drosophila genomics
                      InterPro - A database of protein families, domains and functional sites
                      KEGG Genes - Molecular building blocks of life in the genomic space.
                      MARRVEL_MODEL - MARRVEL (model organism gene)
                      Linkouts
                      Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
                      DroID - A comprehensive database of gene and protein interactions.
                      DRSC - Results frm RNAi screens
                      Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
                      FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
                      FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
                      Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
                      Flygut - An atlas of the Drosophila adult midgut
                      iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
                      Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
                      MIST (genetic) - An integrated Molecular Interaction Database
                      MIST (protein-protein) - An integrated Molecular Interaction Database
                      References (202)