orthologue of a large Maf transcription factor in mammals - gonad development - somatic gonadal cells - follicle cells - germline- soma interactions - a transcriptional target of Hh signaling controlling cell-cell adhesion by negative regulation of E-cadherin expression
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\tj using the Feature Mapper tool.
Within the border cell cluster, tj is expressed more strongly in the polar follicle cells, compared to the rosette cells (non-polar border cells).
tj protein is strongly expressed in cyst cell nuclei and weakly expressed in hub cells.
GBrowse - Visual display of RNA-Seq signalsView Dmel\tj in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: tj CG10034
Source for merge of tj CG10034 was sequence comparison ( date:030729 ).
Identification: PCR product, using primers for conserved sequences among vertebrate maf genes.
Mutants affect normal oogenesis.
The tj locus affects early oogenesis: mutations cause the production of few, defective germ cells.