HEX, HexC, hexokinase, HK, HK-C
Gene model reviewed during 5.50
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Hex-C using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Hex-C in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
The effects of a high sucrose diet on live weight, total protein, stored lipid and glycogen and crude activities of 12 enzymes involved in energy metabolism are quantified. The activities of many enzymes are reduced by the sucrose treatment.
The isoacceptor pattern of tRNA:E4 is altered in l(2)me1 mutant flies, supporting the hypothesis that the l(2)me1 mutation may be a deletion of part of the tRNA:E4 cistrons (and Hex-C) located at 2-72.
The structural gene for hexokinase-C (HEX-C). The enzyme is a monomer of estimated molecular weight 42,000 +/- 3,000 (Moser et al.) or 35,000 (Leigh Brown in Racine, Langley and Voelker, 1980). Activity present in all developmental stages except freshly laid eggs; restricted to fat body in larvae, but present in many organs in adult. Weakly active or inactive in cell line (Debec, 1974). HEX-C activity not necessary for survival; null mutants viable (Burkhart et al., 1984). Purification and biochemical characterization of enzyme described by Moser et al., 1980.