des, Des1, degenerative spermatocyte, l(2)gdh-2, DES-1
Low-frequency RNA-Seq exon junction(s) not annotated.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Gene model reviewed during 5.45
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\ifc using the Feature Mapper tool.
The 2.0kb ifc transcript is strongly expressed in testes. Transcripts are first detected at low levels in newly formed primary spermatocytes located close to the apical tip of the testis. The signal is at a maximum in the large primary spermatocytes located slightly further away from the apical tip and decreases in the mature primary spermatocytes. Only trace levels are detected in mutant testes.
ifc protein appears to be associated with mitochondria during the meiotic cycle as its distribution parallels the distribution of mitochondria as the cycle proceeds. During anaphase/telophase, labelling of the contractile ring is seen. As meiosis is completed, ifc protein becomes localized to the mitochondrial derivatives (Nebenkern) of the spermatids.
GBrowse - Visual display of RNA-Seq signalsView Dmel\ifc in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
ifc encodes a protein that may act as part of an anchoring mechanism that links membrane-bounded cellular compartments to components of the cytoskeleton.
ifc may be required for the initiation of meiosis during spermatogenesis, and may be required for interactions between primary spermatocytes and surrounding somatic cells.
Growth phase defect locus.