FB2026_02 , released June 18, 2026
Gene: Dmel\Pgm1
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General Information
Symbol
Dmel\Pgm1
Species
D. melanogaster
Name
Phosphoglucomutase 1
Annotation Symbol
CG5165
Feature Type
protein_coding_gene
FlyBase ID
FBgn0003076
Gene Model Status
Current
Stock Availability
10 publicly available
Enzyme Name (EC)
phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (5.4.2.2)
Gene Summary
Phosphoglucomutase 1 (Pgm1) encodes an enzyme that catalyzes the reversible isomerization of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate. It is involved in various glucose metabolic processes including glycogen metabolism, glycolysis and galactose metabolism. [Date last reviewed: 2024-09-19] (FlyBase Gene Snapshot)
All Summaries
Also Known As

Pgm, phosphoglucomutase, PGM-1, Phosphoglucose mutase 1, phosphoglucose mutase

Key Links
Genomic Location
Cytogenetic map
72D8-72D8
Sequence location
Recombination map
3-44
RefSeq locus
NT_037436 REGION:16126018..16128531
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (12 terms)
Molecular Function (3 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
enables phosphoglucomutase activity
inferred from mutant phenotype
(Eanes et al., 2006)
inferred from direct assay
(Verrelli and Eanes, 2001, Pontecorvo et al., 1986)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
enables intramolecular phosphotransferase activity
(InterPro Project Members, 2004-)
enables magnesium ion binding
inferred from electronic annotation with InterPro:IPR016066
(InterPro Project Members, 2004-)
enables phosphoglucomutase activity
inferred from electronic annotation with InterPro:IPR045244
(InterPro Project Members, 2004-)
inferred from sequence or structural similarity with UniProtKB:P36871
(Gene Ontology Curators, 2002-)
Biological Process (8 terms)
Terms Based on Experimental Evidence (6 terms)
CV Term
Evidence
References
involved_in glucose 1-phosphate metabolic process
inferred from direct assay
(Verrelli and Eanes, 2001)
involved_in glucose 6-phosphate metabolic process
inferred from direct assay
(Verrelli and Eanes, 2001)
involved_in glycogen biosynthetic process via UDP-glucose
inferred from mutant phenotype
(Verrelli and Eanes, 2001)
involved_in glycogen biosynthetic process
inferred from mutant phenotype
(Verrelli and Eanes, 2001)
involved_in glycogen catabolic process
inferred from mutant phenotype
(Eanes et al., 2006)
involved_in glycolytic process through glucose-1-phosphate
inferred from mutant phenotype
(Eanes et al., 2006)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
involved_in carbohydrate metabolic process
(InterPro Project Members, 2004-)
involved_in galactose catabolic process via UDP-galactose, Leloir pathway
inferred from sequence or structural similarity with UniProtKB:P36871
(Gene Ontology Curators, 2002-)
Cellular Component (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
is_active_in cytosol
inferred by curator
(FlyBase Curators, 2016-)
Gene Group (FlyBase)
Pathway (FlyBase)
Protein Family (UniProt)
Belongs to the phosphohexose mutase family. (Q9VUY9)
Protein Signatures (InterPro)
Catalytic Activity (EC/Rhea)
phosphoglucomutase activity
alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate (5.4.2.2)
RHEA 23536:
Summaries
Gene Snapshot
Phosphoglucomutase 1 (Pgm1) encodes an enzyme that catalyzes the reversible isomerization of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate. It is involved in various glucose metabolic processes including glycogen metabolism, glycolysis and galactose metabolism. [Date last reviewed: 2024-09-19]
Gene Group (FlyBase)
INTRAMOLECULAR PHOSPHOTRANSFERASES -
Intramolecular phosphotransferases catalyze the transfer of a phosphate group from one part of a molecule to another. (Adapted from FBrf0238665.)
Pathway (FlyBase)
GLYCOGEN BIOSYNTHESIS -
Glycogen is a highly branched polymer composed of chains of D-glucose linked linearly by α-1,4-glucosidic bonds and joined together by α-1,6-glucosidic bonds between branch points. It is stored in cytosolic granules and serves as an energy source when food supplies are low. Glycogen synthesis involves the auto-catalyzed synthesis of a glucose oligomer on glycogenin Gyg, followed by linear extension of the glucose oligomer by glycogen synthase Glys, and the formation of branches by glycogen branching enzyme Agbe. In D. melanogaster adults, it is primarily synthesized and stored in the fat body, flight muscles and in the oocyte. (Adapted from FBrf0238357 and PMID:22248338.)
GLYCOGEN CATABOLISM -
Glycogen is a highly branched polymer composed of chains of D-glucose linked linearly by α-1,4-glucosidic bonds and joined together by α-1,6-glucosidic bonds between branch points. It is stored in cytosolic granules and serves as an energy source when food supplies are low. Glycogen catabolism involves the cleavage of α-1,4-glucosidic bonds by glycogen phosphorylase Glyp from the non-reducing ends of the linear chain releasing glucose 1-phosphate. The final four glycosyl residues of each branch are removed in two steps by glycogen debranching enzyme Agl. Alternatively, glycogen can be degraded in the lysosomes via an autophagic process known as glycophagy. In D. melanogaster adults, glycogen is primarily catabolized in the fat body and flight muscles to produce glucose and trehalose. (Adapted from FBrf0238357, FBrf0223427 and PMID:22248338.)
GALACTOSE CATABOLISM -
Galactose is predominantly catabolized via the Leloir pathway into glucose 1-phosphate and UDP-α-D-galactose. Glucose 1-phosphate can be used for glycolysis after its conversion to glucose 6-phosphate by Pgm1 while UDP-α-D-galactose is a precursor for glycosaminoglycan synthesis and lipid and protein glycosylation. (Adapted from FBrf0234321.)
Protein Function (UniProtKB)
Catalyzes the reversible isomerization of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate (PubMed:44190). The mechanism proceeds via the intermediate compound alpha-D-glucose 1,6-bisphosphate (PubMed:44190). This enzyme participates in both the breakdown and synthesis of glucose (PubMed:44190). Enzyme of the glycolytic pathway (Probable). Glycolysis is essential in glial cells but not in neurons; neurons rely on the citric acid cycle for their energy needs, and on lactate and alanine secreted into the hemolymph by glial cells to fuel it (PubMed:26235423).
(UniProt, Q9VUY9)
Phenotypic Description (Red Book; Lindsley and Zimm 1992)
Pgm: Phosphoglucomutase
Structural gene for the glycolytic enzyme phosphoglucomutase [PGM (E.C. 2.7.5.1)], a monomeric protein of 56,000 daltons. Two frequently-occurring electrophoretic variants were isolated and studied by Hjorth (1970a,b) and Trippa et al. (1970, 1971). Later five low-frequency variants were found by Trippa's group (see references in table of alleles). One null allele found in a total of 431 alleles collected in Great Britain (Langley, Voelker, Leigh-Brown, Ohnishi, Dickson, and Montgomery, 1981, Genetics 99: 151-56).
Gene Model and Products
Number of Transcripts
1
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\Pgm1 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry Q9VUY9)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Gene model reviewed during 5.46

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Pgm1-RA
FBtr0075492
NM_079936
1843
560
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
Pgm1-PA
FBpp0075247
60.8
560
6.68
Q9VUY9
NP_524675
AAF49533
Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments
Reported size (kDa)

958 (aa)

(Li, 1992)
Comments
External Data
Subunit Structure (UniProtKB)

Monomer.

(UniProt, Q9VUY9)
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Nucleotide / Polypeptide Records
 
UniProt
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Pgm1 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.28

Transcript Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Pgm1 in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 63 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 7 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Pgm1
Transgenic constructs containing regulatory region of Pgm1
Aberrations (Deficiencies and Duplications) ( 3 )
Inferred from experimentation ( 3 )
Gene disrupted in
Df(3L)Exel6127
(Ryder, 2004.4.26)
Df(3L)th117
(Voelker et al., 1978)
Gene not disrupted in
Df(3L)th113
(Burkhart et al., 1984)
Inferred from location ( 7 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (6)
Hsap\PGM1
14 of 14
Yes
Yes
Hsap\PGM5
13 of 14
No
Yes
Hsap\PGM2
2 of 14
No
No
Hsap\PGM2L1
2 of 14
No
No
Hsap\HPRT1
1 of 14
No
Yes
2  
Hsap\PRTFDC1
1 of 14
No
Yes
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (6)
Rnor\Pgm1
14 of 14
Yes
Yes
Rnor\Pgm5
13 of 14
No
Yes
Rnor\Pgm2l1
2 of 14
No
No
Rnor\Pgm2
2 of 14
No
No
Rnor\Hprt1
1 of 14
No
Yes
Rnor\Prtfdc1
1 of 14
No
Yes
Mus musculus (laboratory mouse) (5)
Mmus\Pgm1
13 of 14
Yes
Yes
Mmus\Pgm5
13 of 14
Yes
Yes
Mmus\Pgm2l1
2 of 14
No
No
Mmus\Pgm2
2 of 14
No
No
Mmus\Hprt
1 of 14
No
Yes
Xenopus tropicalis (Western clawed frog) (7)
Xtro\pgm5
7 of 13
Yes
Yes
Xtro\pgm1
2 of 13
No
Yes
Xtro\bbx
1 of 13
No
No
Xtro\crocc2
1 of 13
No
No
Xtro\galnt3
1 of 13
No
No
Xtro\pgm2l1
1 of 13
No
No
Xtro\slf2
1 of 13
No
No
Danio rerio (Zebrafish) (8)
Drer\pgm1
14 of 14
Yes
Yes
Drer\pgm5
13 of 14
No
Yes
Drer\pgm2
2 of 14
No
No
Drer\pgm2l1
2 of 14
No
No
Drer\hprt1
1 of 14
No
Yes
Drer\hprt1l
1 of 14
No
Yes
Drer\prtfdc1a
1 of 14
No
Yes
Drer\prtfdc1b
1 of 14
No
Yes
Caenorhabditis elegans (Nematode, roundworm) (2)
Cele\R05F9.6
14 of 14
Yes
Yes
Cele\Y43F4B.5
1 of 14
No
No
Anopheles gambiae (African malaria mosquito) (1)
Agam\AgaP_AGAP005860
12 of 12
Yes
Yes
Arabidopsis thaliana (thale-cress) (5)
Atha\PGM
13 of 13
Yes
Yes
Atha\PGM2
12 of 13
No
Yes
Atha\PGM3
12 of 13
No
Yes
Atha\AT1G70820
1 of 13
No
No
Atha\AT5G17530
1 of 13
No
No
Saccharomyces cerevisiae (Brewer's yeast) (3)
Scer\PGM1
13 of 13
Yes
Yes
Scer\PGM2
13 of 13
Yes
Yes
Scer\PRM15
1 of 13
No
No
Schizosaccharomyces pombe (Fission yeast) (2)
Spom\SPBC32F12.10
12 of 12
Yes
Yes
Spom\SPCC1840.05c
1 of 12
No
No
Escherichia coli (enterobacterium) (3)
Ecol\pgm
8 of 11
Yes
Yes
Ecol\cpsG
2 of 11
No
Yes
Ecol\glmM
1 of 11
No
No
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:Pgm1. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (3)
Pgm2a
2 of 13
Pgm2b
2 of 13
nst
1 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 1 )
    Human Ortholog
    Disease
    Evidence
    References
    PGM1; phosphoglucomutase 1
    model of  congenital disorder of glycosylation It
    IEA
    (FlyBase, 2019-)
    Modifiers Based on Experimental Evidence ( 1 )
    Allele
    Disease
    Interaction
    References
    Pgm1HMS01333
    exacerbates  Alzheimer's disease
    modeled by Hsap\APP2xAPP.SP.UAS
    (Minjarez et al., 2016)
    Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    PGM1; phosphoglucomutase 1
    14 of 14
    171900
    PGM5; phosphoglucomutase 5
    13 of 14
    600981
        Functional Complementation Data
        Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
        Interactions
        Summary of Physical Interactions
        Interaction Browsers
        Summary of Genetic Interactions
        Interaction Browsers
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        External Data
        Subunit Structure (UniProtKB)
        Monomer.
        (UniProt, Q9VUY9 )
        Linkouts
        BioGRID - A database of protein and genetic interactions.
        DroID - A comprehensive database of gene and protein interactions.
        MIST (protein-protein) - An integrated Molecular Interaction Database
        Pathways
        Signaling Pathways (FlyBase)
        Metabolic Pathways
        External Data
        Linkouts
        KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
        Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
        Class of Gene
        Genomic Location and Detailed Mapping Data
        Chromosome (arm)
        3L
        Recombination map
        3-44
        Cytogenetic map
        72D8-72D8
        Sequence location
        FlyBase Computed Cytological Location
        Cytogenetic map
        Evidence for location
        72D8-72D8
        Limits computationally determined from genome sequence between P{lacW}thj5C8&P{PZ}Mbs03802 and P{lacW}SsRβs1939
        Experimentally Determined Cytological Location
        Cytogenetic map
        Notes
        References
        72D7-72D7
        (Verrelli, 2000.7.27)
        Experimentally Determined Recombination Data
        Location

        3-44

        (FlyBase, 2016)

        3-38.4

        (Comeron et al., 2012)

        3-

        (Choudhary et al., 1992)
        Left of (cM)
        (Trippa et al., 1971, Hjorth, 1970)
        Right of (cM)
        (Trippa et al., 1971)
        (Hjorth, 1970)
        Notes
        Stocks and Reagents
        Stocks (10)
        Genomic Clones (14)
         

        Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

        cDNA Clones (157)
         

        Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

        cDNA clones, fully sequenced
        BDGP DGC clones
        Other clones
        Drosophila Genomics Resource Center cDNA clones

        For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

        cDNA Clones, End Sequenced (ESTs)
        BDGP DGC clones
        Other clones
        RNAi and Array Information
        Linkouts
        DRSC - Results frm RNAi screens
        Antibody Information
        Laboratory Generated Antibodies
         
        Commercially Available Antibodies
         
        Cell Line Information
        Publicly Available Cell Lines
         
          Other Stable Cell Lines
           
            Other Comments

            The effects of a high sucrose diet on live weight, total protein, stored lipid and glycogen and crude activities of 12 enzymes involved in energy metabolism are quantified. The activities of many enzymes are reduced by the sucrose treatment.

            (Wang and Clark, 1995)

            Gramoxone has no mutagenic effect on the genetic background of Pgm.

            (el Abidin Salam et al., 1993)

            The synergistic effects of the Adh locus, or a tightly linked locus, on the quantities of the Mdh1, Gpdh, Pgm, Idh, Men and Gapdh1 gene products in D.melanogaster derived from an African population has been determined.

            (Li, 1992)

            No difference in allele fixed in lines selected over 700 generations for high (negative) and low (positive) geotaxis.

            (Stoltenberg et al., 1992)

            Heat denaturation, isoelectric focusing and the degree of genetic variation at the Pgm locus has been examined in laboratory populations.

            (Cicchetti et al., 1990)

            Heat denaturation study has been used to detect genetic heterogeneity within electrophoretic classes at the Pgm locus.

            (Trippa et al., 1978)

            Thermostability study of the Pgm locus reveals temperature-resistant and temperature-sensitive mutants.

            (Trippa et al., 1976)

            Structural gene for the glycolytic enzyme phosphoglucomutase (PGM), a monomeric protein of 56,000 daltons. Two frequently-occurring electrophoretic variants were isolated and studied by Hjorth, 1970; Hjorth, 1970 and Trippa et al., 1970; Trippa et al., 1971. Later five low-frequency variants were found by Trippa's group (see references under alleles). One null allele found in a total of 431 alleles collected in Great Britain (Langley, Voelker, Leigh-Brown, Ohnishi, Dickson and Montgomery, 1981).

            Relationship to Other Genes
            Source for database merge of

            Source for merge of: Pgm CG5165

            (FlyBase, 1996-)
            Additional comments

            Source for merge of Pgm CG5165 was sequence comparison ( date:010104 ).

            (FlyBase, 1996-)
            Nomenclature History
            Source for database identify of

            Source for identity of: Pgm1 Pgm

            (FlyBase, 2017-)
            Nomenclature comments

            Renamed from 'Pgm' to 'Pgm1' (i.e. added the '1' suffix) to distinguish this gene from the two Pgm2 genes and consistently reflect orthology to the vertebrate genes.

            (FlyBase, 2017-)
            Etymology
            Synonyms and Secondary IDs (15)
            Reported As
            Symbol Synonym
            CG5165
            (Huynh et al., 2019, Jumbo-Lucioni et al., 2016, Buescher et al., 2013, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Puri et al., 2008, Pile et al., 2003)
            PGM
            (Barrio et al., 2014, Cork and Purugganan, 2004, Deckert-Cruz et al., 2004, Passananti et al., 2004, Clark and Wang, 1997, Wang and Clark, 1995, Clark, 1994, Clark and Wang, 1994, Eanes, 1994, Choudhary et al., 1992, Clark, 1990, Clark et al., 1990)
            PGM-1
            (Buescher et al., 2013, Bondinas et al., 2002, Bondinas et al., 2001)
            PGM1
            (Minjarez et al., 2016)
            Pgm
            (Bar et al., 2025, Zhu et al., 2022, Vásquez-Procopio et al., 2020, Huynh et al., 2019, Cogni et al., 2017, Gáliková et al., 2017, Transgenic RNAi Project members, 2017-, Cogni et al., 2015, Wójtowicz et al., 2015, Lavington et al., 2014, Luck et al., 2014, Whitaker et al., 2014, Clark et al., 2013, O'Sullivan et al., 2013, Japanese National Institute of Genetics, 2012.5.21, Cooper and Kennison, 2011, Eanes, 2011, Ruaud et al., 2011, Font-Burgada et al., 2008, Puri et al., 2008, Domanitskaya et al., 2007, Flowers et al., 2007, Dionne et al., 2006, Eanes et al., 2006, Gronke et al., 2005, Deckert-Cruz et al., 2004, Geiger-Thornsberry and Mackay, 2004, Allikian et al., 2002, Verrelli and Eanes, 2001, Lindsley and Zimm, 1992)
            Pgm-1
            (Kovac and Marinkovic, 1999)
            Pgm1
            (Fisher et al., 2023, Bischof and FlyORF project members, 2014.6.20)
            dPgm
            (Jumbo-Lucioni et al., 2016)
            pgm
            (Rose and Burke, 2011, Roman, 2004)
            Name Synonyms
            Phosphoglucomutase
            (Deckert-Cruz et al., 2004, Geiger-Thornsberry and Mackay, 2004, Passananti et al., 2004, Lindsley and Zimm, 1992)
            Phosphoglucomutase 1
            Phosphogluconate mutase
            Phosphoglucose mutase 1
            (Rice et al., 2020)
            phosphoglucomutase
            (Buescher et al., 2013, Rose and Burke, 2011, Ruaud et al., 2011, Eanes et al., 2006, Gronke et al., 2005, Deckert-Cruz et al., 2004, Kovac and Marinkovic, 1999, Pontecorvo et al., 1986)
            phosphoglucose mutase
            (Clark et al., 2013)
            Secondary FlyBase IDs
            • FBgn0036572
            Datasets (0)
            Study focus (0)
            Experimental Role
            Project
            Project Type
            Title
            Study result (0)
            Result
            Result Type
            Title
            External Crossreferences and Linkouts ( 160 )
            Sequence Crossreferences
            NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
            GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
            GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
            RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
            UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
            UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
            Other crossreferences
            AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
            DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
            EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
            FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
            FlyMine - An integrated database for Drosophila genomics
            InterPro - A database of protein families, domains and functional sites
            KEGG Genes - Molecular building blocks of life in the genomic space.
            MARRVEL_MODEL - MARRVEL (model organism gene)
            Linkouts
            BioGRID - A database of protein and genetic interactions.
            Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
            DroID - A comprehensive database of gene and protein interactions.
            DRSC - Results frm RNAi screens
            Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
            FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
            FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
            FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel
            Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
            Flygut - An atlas of the Drosophila adult midgut
            FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.
            KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.
            KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.
            MIST (protein-protein) - An integrated Molecular Interaction Database
            Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
            Reactome Metabolic Pathways - An open-source, open access, manually curated and peer-reviewed metabolic pathway database.
            References (156)