Lip, Dmp68, p68
DEAD box helicase - involved in generation of precursor-miRNA, double-stranded RNA-mediated silencing, heterochromatin formation, resilencing of active transcription, maintenance of homeotic genes and antiviral immunity
Gene model reviewed during 5.40
Gene model reviewed during 5.50
2.9 (northern blot)
575 (aa); 62 (kD predicted)
Interacts with Fmr1 to form the RNA-induced silencing complex (RISC), a ribonucleoprotein (RNP) complex involved in translation regulation, other components of the complex are RpL5, RpL11, AGO2 and Dcr-1.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Rm62 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Rm62 in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
RNAi screen using dsRNA made from templates generated with primers directed against this gene causes a greater than three-fold increase in AttA activity in response to heat-killed E.coli after ecdysone treatment in S2 cells.
Area matching Drosophila RM62 gene. Acc. No. X52846.
Identification: Enhancer trap expression pattern survey for loci expressed in the ring gland.