FB2021_01, released Feb 18, 2021

Gene: Dmel\Rm62

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General Information
Symbol
Dmel\Rm62
Species
D. melanogaster
Name
Rm62
Annotation Symbol
CG10279
Feature Type
protein_coding_gene
FlyBase ID
FBgn0003261
Gene Model Status
Current
Stock Availability
22 publicly available
Gene Snapshot
Contributions welcome
Other Summaries
Also Known As

Lip, Dmp68, p68

Key Links
Genomic Location
Cytogenetic map
83D1-83D2
Sequence location
3R:6,000,426..6,008,579 [-]
Recombination map

3-47.5

RefSeq locus
NT_033777 REGION:6000426..6008579
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (16 terms)
Molecular Function (5 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
enables protein binding
inferred from physical interaction with FLYBASE:Fmr1; FB:FBgn0028734
(Ishizuka et al., 2002)
Terms Based on Predictions or Assertions (4 terms)
CV Term
Evidence
References
enables ATP binding
inferred from electronic annotation with InterPro:IPR011545
(assigned by InterPro )
(FlyBase Curators et al., 2004-)
enables mRNA binding
inferred from sequence or structural similarity
(Lasko, 2000)
enables RNA binding
inferred from biological aspect of ancestor with PANTHER:PTN002774595
(assigned by GO_Central )
(Gaudet et al., 2011)
enables RNA helicase activity
inferred from biological aspect of ancestor with PANTHER:PTN002774595
(assigned by GO_Central )
(Gaudet et al., 2011)
Biological Process (4 terms)
Terms Based on Experimental Evidence (3 terms)
CV Term
Evidence
References
involved_in regulation of alternative mRNA splicing, via spliceosome
inferred from high throughput mutant phenotype
(Park et al., 2004)
involved_in regulation of defense response to virus
inferred from mutant phenotype
(Moy et al., 2014)
involved_in RNA interference
inferred from mutant phenotype
(Ishizuka et al., 2002)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
involved_in mRNA splicing, via spliceosome
inferred by curator from GO:0071011,GO:0071013
(Herold et al., 2009)
involved_in RNA interference
inferred from biological aspect of ancestor with PANTHER:PTN002774068
(assigned by GO_Central )
(Gaudet et al., 2011)
Cellular Component (7 terms)
Terms Based on Experimental Evidence (6 terms)
CV Term
Evidence
References
part_of catalytic step 2 spliceosome
inferred from high throughput direct assay
(Herold et al., 2009)
located_in cytoplasm
inferred from high throughput direct assay
(Lee et al., 2014)
located_in nucleus
inferred from direct assay
(Gerbasi et al., 2011)
inferred from high throughput direct assay
(Lye et al., 2014)
located_in polytene chromosome puff
inferred from direct assay
(Buszczak and Spradling, 2006)
located_in polytene chromosome
inferred from direct assay
(Lamiable et al., 2010)
part_of precatalytic spliceosome
inferred from high throughput direct assay
(Herold et al., 2009)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
located_in cytoplasm
inferred from biological aspect of ancestor with PANTHER:PTN002773962
(assigned by GO_Central )
(Gaudet et al., 2011)
located_in nucleus
inferred from biological aspect of ancestor with PANTHER:PTN002773962
(assigned by GO_Central )
(Gaudet et al., 2011)
inferred by curator from GO:0000381
(Park et al., 2004)
part_of ribonucleoprotein complex
inferred from biological aspect of ancestor with PANTHER:PTN002773962
(assigned by GO_Central )
(Gaudet et al., 2011)
Gene Group (FlyBase)
Protein Family (UniProt)
Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily. (P19109)
Protein Signatures (InterPro)
Summaries
Gene Group (FlyBase)
DEAD-BOX RNA HELICASES -
DEAD-box RNA helicases belong to helicase superfamily 2 (SF2). They are characterized by the presence of nine conserved helicase motifs, including the DEAD sequence in motif II. (Adapted from PMID:21509200.)
Protein Function (UniProtKB)
As an RNA helicase, unwinds RNA and alters RNA structures through ATP binding and hydrolysis. Involved in multiple cellular processes, including pre-mRNA splicing, alternative splicing, rRNA processing and miRNA processing, as well as transcription regulation (By similarity) (PubMed:12368261). Plays a role in innate immunity. Specifically restricts bunyavirus infection, including Rift Valley fever virus (RVFV) or La Crosse virus (LACV), but not vesicular stomatitis virus (VSV), in an interferon- and DROSHA-independent manner (PubMed:25126784).
(UniProt, P19109)
Summary (Interactive Fly)

DEAD box helicase - involved in generation of precursor-miRNA, double-stranded RNA-mediated silencing, heterochromatin formation, resilencing of active transcription, maintenance of homeotic genes and antiviral immunity

Gene Model and Products
Number of Transcripts
12
Number of Unique Polypeptides
8

Please see the JBrowse view of Dmel\Rm62 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Gene model reviewed during 5.40

Gene model reviewed during 5.50

Sequence Ontology: Class of Gene
gene_with_edited_transcript
(Rodriguez et al., 2012, Graveley et al., 2011)
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Rm62-RA
FBtr0078652
NM_079519
2995
719
Rm62-RB
FBtr0078651
NM_169122
3087
578
Rm62-RC
FBtr0078649
NM_169120
2849
578
Rm62-RD
FBtr0078650
NM_169118
2757
575
Rm62-RE
FBtr0078653
NM_169119
3160
578
Rm62-RF
FBtr0078654
NM_169121
2833
578
Rm62-RH
FBtr0301947
NM_001170057
2760
575
Rm62-RI
FBtr0302597
NM_001202253
3153
578
Rm62-RJ
FBtr0309319
NM_001260009
4362
458
Rm62-RK
FBtr0309320
NM_001260010
3683
485
Rm62-RL
FBtr0309321
NM_001260011
3793
473
Rm62-RM
FBtr0309322
NM_001260012
3411
478
Additional Transcript Data and Comments
Reported size (kB)

2.9 (northern blot)

(Dorer et al., 1990)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
Rm62-PA
FBpp0078301
78.5
719
10.06
NP_524243
AAG22213
Rm62-PB
FBpp0078300
62.9
578
10.02
NP_731035
AAF51926
Rm62-PC
FBpp0078298
62.9
578
10.02
NP_731033
AAN14332
Rm62-PD
FBpp0078299
62.5
575
10.02
NP_731031
AAN14331
Rm62-PE
FBpp0078302
62.8
578
10.12
NP_731032
AAF51927
Rm62-PF
FBpp0078303
62.9
578
10.02
NP_731034
AAG22212
Rm62-PH
FBpp0291159
62.5
575
10.02
NP_001163528
ACZ94826
Rm62-PI
FBpp0291753
62.8
578
10.12
NP_001189182
ADV37273
Rm62-PJ
FBpp0301223
50.1
458
9.77
NP_001246938
AFH06257
Rm62-PK
FBpp0301224
53.2
485
9.77
NP_001246939
AFH06258
Rm62-PL
FBpp0301225
52.0
473
9.78
NP_001246940
AFH06259
Rm62-PM
FBpp0301226
52.5
478
9.55
NP_001246941
AFH06260
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

578 aa isoforms: Rm62-PB, Rm62-PC, Rm62-PF
575 aa isoforms: Rm62-PD, Rm62-PH
578 aa isoforms: Rm62-PE, Rm62-PI
Additional Polypeptide Data and Comments
Reported size (kDa)

575 (aa); 62 (kD predicted)

(Dorer et al., 1990)
Comments
External Data
Subunit Structure (UniProtKB)

Interacts with Fmr1 to form the RNA-induced silencing complex (RISC), a ribonucleoprotein (RNP) complex involved in translation regulation, other components of the complex are RpL5, RpL11, AGO2 and Dcr-1.

(UniProt, P19109)
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Nucleotide / Polypeptide Records
 
UniProt
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Rm62 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 1 -- 3
organism

Comment: maternally deposited

(Fisher et al., 2012)
embryonic stage 4 -- 6
organism
(Fisher et al., 2012)
embryonic stage 7 -- 8
organism | ubiquitous
(Fisher et al., 2012)
embryonic stage 9 -- 10
organism | ubiquitous
(Fisher et al., 2012)
embryonic stage 11 -- 12
organism | ubiquitous
(Fisher et al., 2012)
embryonic stage 13 -- 16
organism | ubiquitous
(Fisher et al., 2012)
northern blot
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage
(Dorer et al., 1990)
larval stage
(Dorer et al., 1990)
adult stage
(Dorer et al., 1990)
Additional Descriptive Data

Isoform-specific expression patterns are observed. Sex-specific expression of alternative transcripts observed.

(Telonis-Scott et al., 2009)

Rm62 transcripts are detected on northern blots in all developmental stages tested.

(Dorer et al., 1990)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
day 7 of adulthood -- day 49 of adulthood
adult heart
(Cammarato et al., 2011)
adult stage
adult head
(Aradska et al., 2015)
western blot
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage
organism
(Lamiable et al., 2010)
first instar larval stage
ventral thoracic disc
(Lamiable et al., 2010)
larval stage
wing disc
(Lamiable et al., 2010)
haltere disc
(Lamiable et al., 2010)
third instar larval stage
ventral thoracic disc
(Lamiable et al., 2010)
adult stage | female
ovary
(Lamiable et al., 2010)
adult stage | male
testis
(Lamiable et al., 2010)
adult stage
adult head
(Lamiable et al., 2010)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
part_of catalytic step 2 spliceosome
inferred from high throughput direct assay
(Herold et al., 2009)
located_in cytoplasm
inferred from high throughput direct assay
(Lee et al., 2014)
located_in nucleus
inferred from direct assay
(Gerbasi et al., 2011)
inferred from high throughput direct assay
(Lye et al., 2014)
located_in polytene chromosome puff
inferred from direct assay
(Buszczak and Spradling, 2006)
located_in polytene chromosome
inferred from direct assay
(Lamiable et al., 2010)
part_of precatalytic spliceosome
inferred from high throughput direct assay
(Herold et al., 2009)
Expression Deduced from Reporters
Reporter: PBac{806.LOX-SVS-2}Rm62CPTI004179
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult brain cell body rind
(Knowles-Barley, 2011.8.24)
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Rm62 in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 38 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 9 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Rm62
Transgenic constructs containing regulatory region of Rm62
Aberrations (Deficiencies and Duplications) ( 7 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal
lethal, with Scer\GAL4Act5C.PI
lethal, with Scer\GAL4Act88F.PU
lethal, with Scer\GAL4en.PU
lethal, with Scer\GAL4Mef2.PU
lethal, with Scer\GAL4nub.PK
lethal (with Rm6201086)
lethal (with Rm62CB02119)
lethal (with Rm62D)
lethal (with Rm62F)
lethal (with Rm62H)
lethal (with Rm62K)
lethal | female limited, with Scer\GAL4dome-PG14
lethal | recessive
partially lethal - majority die, with Scer\GAL4pnr-MD237
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4tin.CΔ4
viable (with Rm6201086)
viable (with Rm62CB02119)
viable (with Rm62D)
viable (with Rm62E)
Sterility
Allele
female sterile
female sterile, with Scer\GAL4VP16.otu
male sterile
sterile
sterile (with Rm6201086)
sterile (with Rm62CB02119)
Other Phenotypes
Allele
abnormal developmental rate | larval stage (with Rm62CB02119)
abnormal developmental rate | larval stage (with Rm62F)
abnormal flight, with Scer\GAL4Act88F.PU
abnormal immune response, with Scer\GAL4hs.PU
abnormal immune response (with Rm6201086)
abnormal immune response (with Rm62CB02119)
abnormal neuroanatomy | larval stage
abnormal size | adult stage, with Scer\GAL4ey.PH
abnormal size | pharate adult stage, with Scer\GAL4Act88F.PU
flightless, with Scer\GAL4Mef2.PR
some die during pupal stage, with Scer\GAL4pnr-MD237
visible, with Scer\GAL4nub-AC-62
visible, with Scer\GAL4pnr-MD237
visible | adult stage, with Scer\GAL4ey.PH
visible | adult stage, with Scer\GAL4GMR.PF
visible | dominant
Phenotype manifest in
Allele
dorsocentral bristle (with Rm6201086)
dorsocentral bristle (with Rm62CB02119)
egg chamber (with Rm6201086)
egg chamber (with Rm62CB02119)
eye, with Scer\GAL4ey.PH
eye, with Scer\GAL4GMR.PF
ganglion mother cell | larval stage
indirect flight muscle | pharate adult stage, with Scer\GAL4Act88F.PU
larval multidendritic class IV neuron | somatic clone, with Scer\GAL4Act.PU
mesothoracic tergum, with Scer\GAL4pnr-MD237
myofibril | pharate adult stage, with Scer\GAL4Act88F.PU
nurse cell & nuclear chromosome (with Rm6201086)
nurse cell & nuclear chromosome (with Rm62CB02119)
pigment cell
scutellar bristle (with Rm6201086)
scutellar bristle (with Rm62CB02119)
trichogen cell, with Scer\GAL4pnr-MD237
wing, with Scer\GAL4nub-AC-62
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (12)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\DDX17
9 of 15
Yes
No
Hsap\DDX5
8 of 15
No
No
Hsap\DDX43
2 of 15
No
No
Hsap\DDX21
1 of 15
No
Yes
Hsap\DDX42
1 of 15
No
No
Hsap\DDX46
1 of 15
No
No
Hsap\DDX50
1 of 15
No
Yes
Hsap\DDX53
1 of 15
No
No
Hsap\DDX55
1 of 15
No
No
Hsap\DDX59
1 of 15
No
Yes
Hsap\GPR149
1 of 15
No
No
Hsap\TDRD12
1 of 15
No
No
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (11)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Ddx17
9 of 15
Yes
No
Mmus\Ddx5
8 of 15
No
No
Mmus\Ddx3x
1 of 15
No
No
Mmus\Ddx21
1 of 15
No
Yes
Mmus\Ddx43
1 of 15
No
No
Mmus\Ddx46
1 of 15
No
No
Mmus\Ddx50
1 of 15
No
Yes
Mmus\Ddx55
1 of 15
No
No
Mmus\Ddx59
1 of 15
No
Yes
Mmus\Gpr149
1 of 15
No
No
Mmus\Tdrd12
1 of 15
No
Yes
Rattus norvegicus (Norway rat) (12)
Rnor\Ddx5
7 of 13
Yes
No
Rnor\Ddx3y
1 of 13
No
No
Rnor\Ddx17
1 of 13
No
Yes
Rnor\Ddx21
1 of 13
No
Yes
Rnor\Ddx42
1 of 13
No
No
Rnor\Ddx43
1 of 13
No
No
Rnor\Ddx46
1 of 13
No
No
Rnor\Ddx50
1 of 13
No
Yes
Rnor\Ddx55
1 of 13
No
No
Rnor\Ddx59
1 of 13
No
Yes
Rnor\Gpr149
1 of 13
No
No
Rnor\Tdrd12
1 of 13
No
Yes
Xenopus tropicalis (Western clawed frog) (8)
Xtro\ddx5
6 of 12
Yes
No
Xtro\ddx17
4 of 12
No
No
Xtro\ddx21
1 of 12
No
Yes
Xtro\ddx42
1 of 12
No
No
Xtro\ddx43
1 of 12
No
No
Xtro\ddx46
1 of 12
No
No
Xtro\ddx59
1 of 12
No
Yes
Xtro\gpr149
1 of 12
No
No
Danio rerio (Zebrafish) (8)
Drer\ddx5
8 of 15
Yes
No
Drer\si:dkey-156n14.5
8 of 15
Yes
No
Drer\ddx21
1 of 15
No
Yes
Drer\ddx42
1 of 15
No
No
Drer\ddx43
1 of 15
No
No
Drer\ddx46
1 of 15
No
No
Drer\ddx59
1 of 15
No
Yes
Drer\tdrd12
1 of 15
No
Yes
Caenorhabditis elegans (Nematode, roundworm) (4)
Cele\ddx-17
10 of 15
Yes
No
Cele\Y54G11A.3
2 of 15
No
No
Cele\C46F11.4
1 of 15
No
No
Cele\F53H1.1
1 of 15
No
No
Arabidopsis thaliana (thale-cress) (8)
Atha\RH20
7 of 9
Yes
No
Atha\AT5G63120
6 of 9
No
No
Atha\AT1G20920
1 of 9
No
No
Atha\AT2G47330
1 of 9
No
No
Atha\AT3G06480
1 of 9
No
Yes
Atha\AT3G09620
1 of 9
No
No
Atha\AT5G14610
1 of 9
No
Yes
Atha\DRH1
1 of 9
No
Yes
Saccharomyces cerevisiae (Brewer's yeast) (3)
Scer\DBP2
11 of 15
Yes
No
Scer\DBP3
3 of 15
No
Yes
Scer\PRP5
2 of 15
No
No
Schizosaccharomyces pombe (Fission yeast) (2)
Spom\dbp2
10 of 12
Yes
No
Spom\dbp3
2 of 12
No
Yes
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG091904ZO )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00011758
Drosophila sechellia
Dsec\GM10578
Drosophila erecta
Dere\GG10666
Drosophila yakuba
Dyak\GE24123
Drosophila ananassae
Dana\GF18634
Drosophila pseudoobscura pseudoobscura
Dpse\GA10214
Drosophila persimilis
Dper\GL23489
Drosophila willistoni
Dwil\GK14214
Drosophila virilis
Dvir\GJ14499
Drosophila mojavensis
Dmoj\GI23184
Drosophila grimshawi
Dgri\GH14289
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091504CE )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17022318
Musca domestica
House fly
Mdoa\17017471
Musca domestica
House fly
Mdoa\17012377
Glossina morsitans
Tsetse fly
Gmor\GMOY002040
Glossina morsitans
Tsetse fly
Gmor\GMOY004318
Glossina morsitans
Tsetse fly
Gmor\GMOY004429
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_04267
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_14185
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_11837
Mayetiola destructor
Hessian fly
Mdes\Mdes009004
Mayetiola destructor
Hessian fly
Mdes\Mdes002581
Mayetiola destructor
Hessian fly
Mdes\Mdes002582
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL001769
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL002083
Anopheles darlingi
American malaria mosquito
Adar\ADAC006310
Anopheles darlingi
American malaria mosquito
Adar\ADAC001628
Anopheles gambiae
Malaria mosquito
Agam\AGAP005652
Anopheles gambiae
Malaria mosquito
Agam\AGAP004912
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ016569
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ014935
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W05E4 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA006461
Bombyx mori
Silkmoth
Bmor\BGIBMGA011754
Bombyx mori
Silkmoth
Bmor\BGIBMGA001336
Bombyx mori
Silkmoth
Bmor\BGIBMGA011965
Bombyx mori
Silkmoth
Bmor\BGIBMGA011746
Danaus plexippus
Monarch butterfly
Dple\DPOGS208294-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS204857-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS214267-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS210327-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS207282-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL015763
Heliconius melpomene
Postman butterfly
Hmel\HMEL013900
Heliconius melpomene
Postman butterfly
Hmel\HMEL008369
Heliconius melpomene
Postman butterfly
Hmel\HMEL011392
Heliconius melpomene
Postman butterfly
Hmel\HMEL013855
Apis florea
Little honeybee
Aflo\2784033716
Apis florea
Little honeybee
Aflo\2510388244
Apis florea
Little honeybee
Aflo\2711705620
Apis florea
Little honeybee
Aflo\2784033684
Apis florea
Little honeybee
Aflo\3816831412
Apis florea
Little honeybee
Aflo\2164632324
Apis mellifera
Western honey bee
Amel\LOC411250
Apis mellifera
Western honey bee
Amel\GB42277
Apis mellifera
Western honey bee
Amel\GB42279
Apis mellifera
Western honey bee
Amel\GB55074
Apis mellifera
Western honey bee
Amel\DDX17
Apis mellifera
Western honey bee
Amel\GB47313
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP17945
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP17187
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP19478
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP21809
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP21811
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP11048
Bombus terrestris
Buff-tailed bumblebee
Bter\15211051
Bombus terrestris
Buff-tailed bumblebee
Bter\15206687
Bombus terrestris
Buff-tailed bumblebee
Bter\15206688
Bombus terrestris
Buff-tailed bumblebee
Bter\15212533
Bombus terrestris
Buff-tailed bumblebee
Bter\15209015
Bombus terrestris
Buff-tailed bumblebee
Bter\15204964
Linepithema humile
Argentine ant
Lhum\LH15923
Linepithema humile
Argentine ant
Lhum\LH19480
Linepithema humile
Argentine ant
Lhum\LH15925
Linepithema humile
Argentine ant
Lhum\LH17582
Linepithema humile
Argentine ant
Lhum\LH13497
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:00310c
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:002e4d
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:00309b
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:0000c4
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:00241b
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG013719
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG001000
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG013735
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG018341
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG013731
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_00056
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_00234
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_12420
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_12421
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_10867
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_00944
Tribolium castaneum
Red flour beetle
Tcas\TC001529
Tribolium castaneum
Red flour beetle
Tcas\TC031754
Tribolium castaneum
Red flour beetle
Tcas\TC002367
Tribolium castaneum
Red flour beetle
Tcas\TC010324
Pediculus humanus
Human body louse
Phum\PHUM521070
Pediculus humanus
Human body louse
Phum\PHUM580220
Pediculus humanus
Human body louse
Phum\PHUM280650
Pediculus humanus
Human body louse
Phum\PHUM044400
Rhodnius prolixus
Kissing bug
Rpro\RPRC012792
Rhodnius prolixus
Kissing bug
Rpro\RPRC005966
Rhodnius prolixus
Kissing bug
Rpro\RPRC012397
Rhodnius prolixus
Kissing bug
Rpro\RPRC009634
Cimex lectularius
Bed bug
Clec\CLEC013503
Cimex lectularius
Bed bug
Clec\CLEC002214-PC
Cimex lectularius
Bed bug
Clec\CLEC002214-PB
Cimex lectularius
Bed bug
Clec\CLEC002214
Cimex lectularius
Bed bug
Clec\CLEC007424
Cimex lectularius
Bed bug
Clec\CLEC004358
Cimex lectularius
Bed bug
Clec\CLEC004362
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI008547
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI005208
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI081909
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI003571
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI006679
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_03761
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_09472
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_05302
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_03764
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_03770
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_03762
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X05AB )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR006009
Strigamia maritima
European centipede
Smar\SMAR007381
Strigamia maritima
European centipede
Smar\SMAR013983
Ixodes scapularis
Black-legged tick
Isca\ISCW002701
Ixodes scapularis
Black-legged tick
Isca\ISCW002703
Ixodes scapularis
Black-legged tick
Isca\ISCW009472
Ixodes scapularis
Black-legged tick
Isca\ISCW005620
Stegodyphus mimosarum
African social velvet spider
Smim\KFM70435.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM70253.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM66710.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur11g01640
Tetranychus urticae
Two-spotted spider mite
Turt\tetur01g08700
Tetranychus urticae
Two-spotted spider mite
Turt\tetur01g08300
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_299765
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_213150
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_299766
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G033A )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Clk2
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Ddx5_17L
Ciona intestinalis
Vase tunicate
Cint\LOC100183169
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000007926
Gallus gallus
Domestic chicken
Ggal\DDX5
Gallus gallus
Domestic chicken
Ggal\DDX17
Gallus gallus
Domestic chicken
Ggal\ENSGALG00000028438
Gallus gallus
Domestic chicken
Ggal\CLK4
Gallus gallus
Domestic chicken
Ggal\ENSGALG00000014632
Gallus gallus
Domestic chicken
Ggal\CLK3
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (31)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
CG10077
9 of 10
mahe
8 of 10
CG7878
4 of 10
CG6418
3 of 10
CG14443
3 of 10
Prp5
3 of 10
abs
2 of 10
bel
2 of 10
CG5589
2 of 10
CG5800
2 of 10
CG7483
2 of 10
CG8611
2 of 10
CG9143
2 of 10
CG9253
2 of 10
CG9630
2 of 10
CG10333
2 of 10
CG32344
2 of 10
Dbp21E2
2 of 10
Dbp45A
2 of 10
Dbp73D
2 of 10
Dbp80
2 of 10
Ddx1
2 of 10
eIF4A
2 of 10
Gem3
2 of 10
Hel25E
2 of 10
Hlc
2 of 10
me31B
2 of 10
pit
2 of 10
Rs1
2 of 10
vas
2 of 10
mus301
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    DDX17; DEAD-box helicase 17
    9 of 15
    608469
        DDX5; DEAD-box helicase 5
        8 of 15
        180630
            Functional Complementation Data
            Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
            Interactions
            Summary of Physical Interactions
            esyN Network Diagram
            Show neighbor-neighbor interactions:
            Select Layout:
            Legend:
            Protein
            RNA
            Selected Interactor(s)
            Interactions Browser
            View in Interactions Browser
            Please see the Physical Interaction reports below for full details
            RNA-protein
            Physical Interaction
            Assay
            References
            Rm62 - aub
            iclip, partial RNA sequence identification
            (Ma et al., 2017)
            protein-protein
            Physical Interaction
            Assay
            References
            Rm62
            pull down, autoradiography
            (Boeke et al., 2011)
            Rm62 - AGO2
            anti tag coimmunoprecipitation, Identification by mass spectrometry, western blot
            (Lee et al., 2018, Ishizuka et al., 2002)
            Rm62 - Cp190
            anti bait coimmunoprecipitation, western blot, peptide massfingerprinting
            (Moshkovich et al., 2011, Lei and Corces, 2006)
            Rm62 - Dsp1
            anti tag coimmunoprecipitation, western blot, cosedimentation through density gradient, anti bait coimmunoprecipitation, Identification by mass spectrometry
            (Lamiable et al., 2010)
            Rm62 - Fmr1
            anti bait coimmunoprecipitation, western blot, anti tag coimmunoprecipitation, Identification by mass spectrometry, pull down, autoradiography, anti tag western blot, peptide massfingerprinting
            (Lee et al., 2018, Ishizuka et al., 2002)
            Rm62 - Pdk1
            anti tag coimmunoprecipitation, Identification by mass spectrometry
            (Vinayagam et al., 2016)
            Rm62 - Pi3K92E
            anti tag coimmunoprecipitation, Identification by mass spectrometry
            (Vinayagam et al., 2016)
            Rm62 - Pten
            anti tag coimmunoprecipitation, Identification by mass spectrometry
            (Vinayagam et al., 2016)
            Rm62 - Pur-α
            pull down, western blot, autoradiography, Identification by mass spectrometry
            (Qurashi et al., 2011)
            Rm62 - Rheb
            anti tag coimmunoprecipitation, Identification by mass spectrometry
            (Vinayagam et al., 2016)
            Rm62 - S6kII
            anti tag coimmunoprecipitation, Identification by mass spectrometry
            (Vinayagam et al., 2016)
            Rm62 - SmD1
            anti tag coimmunoprecipitation, anti tag western blot
            (Xiong et al., 2013)
            Rm62 - Su(var)3-9
            anti bait coimmunoprecipitation, anti tag western blot, pull down, autoradiography, affinity chromatography technology, Identification by mass spectrometry
            (Boeke et al., 2011)
            Rm62 - Tdrd3
            coimmunoprecipitation, Identification by mass spectrometry, anti tag coimmunoprecipitation, western blot, anti bait coimmunoprecipitation
            (Lee et al., 2018)
            Rm62 - Thor
            anti tag coimmunoprecipitation, Identification by mass spectrometry
            (Vinayagam et al., 2016)
            Rm62 - Top3β
            anti tag coimmunoprecipitation, Identification by mass spectrometry, western blot
            (Lee et al., 2018)
            Rm62 - Tsc1
            anti tag coimmunoprecipitation, Identification by mass spectrometry
            (Vinayagam et al., 2016)
            Rm62 - d
            anti tag coimmunoprecipitation, peptide massfingerprinting
            (Kwon et al., 2013)
            Rm62 - foxo
            anti tag coimmunoprecipitation, Identification by mass spectrometry
            (Vinayagam et al., 2016)
            Rm62 - gig
            anti tag coimmunoprecipitation, Identification by mass spectrometry
            (Vinayagam et al., 2016)
            Rm62 - melt
            anti tag coimmunoprecipitation, Identification by mass spectrometry
            (Vinayagam et al., 2016)
            Rm62 - vas
            anti tag coimmunoprecipitation, Identification by mass spectrometry, western blot
            (Durdevic and Ephrussi, 2019)
            Summary of Genetic Interactions
            esyN Network Diagram
            esyN Network Key:
            Suppression
            Enhancement
            View in Interactions Browser
            Please look at the allele data for full details of the genetic interactions
            Starting gene(s)
            Interaction type
            Interacting gene(s)
            Reference
            Starting gene(s)
            Interaction type
            Interacting gene(s)
            Reference
            bw
            suppressible
            Rm62
            (Schneiderman et al., 2010)
            Fmr1
            suppressible
            Rm62
            (Cziko et al., 2009)
            Pc
            enhanceable
            Rm62
            (Lamiable et al., 2010)
            w
            enhanceable
            Rm62
            (Csink, 1997.12.9, Csink et al., 1994)
            w
            suppressible
            Rm62
            (Csink et al., 1994)
            External Data
            Subunit Structure (UniProtKB)
            Interacts with Fmr1 to form the RNA-induced silencing complex (RISC), a ribonucleoprotein (RNP) complex involved in translation regulation, other components of the complex are RpL5, RpL11, AGO2 and Dcr-1.
            (UniProt, P19109 )
            Linkouts
            BioGRID - A database of protein and genetic interactions.
            DroID - A comprehensive database of gene and protein interactions.
            InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
            MIST (genetic) - An integrated Molecular Interaction Database
            MIST (protein-protein) - An integrated Molecular Interaction Database
            Pathways
            Signaling Pathways (FlyBase)
            Metabolic Pathways
            External Data
            Linkouts
            KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
            Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
            Genomic Location and Detailed Mapping Data
            Chromosome (arm)
            3R
            Recombination map

            3-47.5

            Cytogenetic map
            83D1-83D2
            Sequence location
            3R:6,000,426..6,008,579 [-]
            FlyBase Computed Cytological Location
            Cytogenetic map
            Evidence for location
            83D1-83D2
            Limits computationally determined from genome sequence between P{lacW}casj1C2 and P{PZ}lab01241
            Experimentally Determined Cytological Location
            Cytogenetic map
            Notes
            References
            83D4-83D5
            (determined by in situ hybridisation)
            (Spradling et al., 1999)
            83D4-83D5
            83D1--2 83D2--3 83D3--5
            (BDGP Project Members, 1994-1999)
            Experimentally Determined Recombination Data
            Location

            3-47.5

            (FlyBase, 2016)

            3-44.1

            (Comeron et al., 2012)
            Left of (cM)
            (Csink et al., 1994)
            Right of (cM)
            (Csink et al., 1994)
            Notes
            Stocks and Reagents
            Stocks (22)
            Genomic Clones (21)
            cDNA Clones (486)
             

            Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

            cDNA clones, fully sequenced
            BDGP DGC clones
            Other clones
            Drosophila Genomics Resource Center cDNA clones

            For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

            cDNA Clones, End Sequenced (ESTs)
            BDGP DGC clones
            Other clones
            RNAi and Array Information
            Linkouts
            DRSC - Results frm RNAi screens
            GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
            Antibody Information
            Laboratory Generated Antibodies
             

            monoclonal

            (Boeke et al., 2011)

            polyclonal

            (Lei and Corces, 2006)
            Commercially Available Antibodies
             
            Other Information
            Relationship to Other Genes
            Source for database identify of

            Source for identity of: Rm62 CG10279

            (Zhang, 1999.11)
            Source for database merge of

            Source for merge of: Rm62 Lip

            (FlyBase, 1996-)
            Additional comments
            Other Comments

            RNAi screen using dsRNA made from templates generated with primers directed against this gene causes a greater than three-fold increase in AttA activity in response to heat-killed E.coli after ecdysone treatment in S2 cells.

            (Kleino et al., 2005)

            Area matching Drosophila RM62 gene. Acc. No. X52846.

            (Davies, 2001.3.15)

            Identification: Enhancer trap expression pattern survey for loci expressed in the ring gland.

            (Harvie et al., 1998)

            Isolated in a mutagenic screen to detect dominant second site modifiers of wbl. Rm62 may have a role in chromatin configuration, mutations decrease the spread of heterochromatin into euchromatin and act as a suppressor of position effect variegation.

            (Csink et al., 1994)
            Origin and Etymology
            Discoverer
            Etymology
            Identification
            External Crossreferences and Linkouts ( 104 )
            Sequence Crossreferences
            NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
            GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
            GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
            RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
            UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
            UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
            Other crossreferences
            BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
            Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
            Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
            Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
            Flygut - An atlas of the Drosophila adult midgut
            GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
            iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
            InterPro - A database of protein families, domains and functional sites
            KEGG Genes - Molecular building blocks of life in the genomic space.
            modMine - A data warehouse for the modENCODE project
            Linkouts
            BioGRID - A database of protein and genetic interactions.
            DPiM - Drosophila Protein interaction map
            DroID - A comprehensive database of gene and protein interactions.
            DRSC - Results frm RNAi screens
            FLIGHT - Cell culture data for RNAi and other high-throughput technologies
            FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
            FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
            FlyMine - An integrated database for Drosophila genomics
            Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
            InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
            KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
            MIST (genetic) - An integrated Molecular Interaction Database
            MIST (protein-protein) - An integrated Molecular Interaction Database
            Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
            Synonyms and Secondary IDs (18)
            Reported As
            Symbol Synonym
            4136
            (Harvie et al., 1998)
            CG10279
            (Kolkhof et al., 2017, Çiçek et al., 2016, Brooks et al., 2015, Hosono et al., 2015, Rosa-Ferreira et al., 2015, Sabath et al., 2013, Cammarato et al., 2011, Ni et al., 2011.7.19, Ni et al., 2010.12.1, Schneiderman et al., 2010, Herold et al., 2009, Keleman et al., 2009.8.5, Perkins et al., 2009, Shpargel et al., 2009, Hughes et al., 2008, Ni et al., 2008, Olson et al., 2007, Quinones-Coello, 2007, Duncan et al., 2006, McIntyre et al., 2006, Ishizuka et al., 2002)
            DmRH8
            (Boudet et al., 2001)
            Dmp68
            (Cziko et al., 2009, Kavi and Birchler, 2009, Lei and Corces, 2006, Zhang and Broadie, 2005, Denli and Hannon, 2003, Ishizuka et al., 2002)
            Lip
            (Kavi and Birchler, 2009, Buszczak and Spradling, 2006, Lei and Corces, 2006, Lei and Corces, 2006, Mason et al., 2004, Spradling et al., 1999, Csink, 1997.12.9, Csink et al., 1994)
            RM62
            (Gerbasi et al., 2011, Kolaczkowski et al., 2011, Lei et al., 2008, Sofola et al., 2007, Bidet et al., 2003, Boudet et al., 2001, Barry et al., 1999, Eisen et al., 1998, Dorer et al., 1995, Dorer et al., 1990)
            Rm62
            (Taschuk et al., 2020, Fingerhut et al., 2019, Nikonova et al., 2019, Xing et al., 2019, Lee et al., 2018, Wang et al., 2018, Hsu and Drummond-Barbosa, 2017, Kong et al., 2017, Laflamme et al., 2017, Ma et al., 2017, Transgenic RNAi Project members, 2017-, Cugusi et al., 2016, Lee et al., 2016, Sarov et al., 2016, Tan et al., 2016, Brooks et al., 2015, Dent et al., 2015, Dietz et al., 2015, Fear et al., 2015, Gene Disruption Project members, 2015-, Jambor et al., 2015, Kwong et al., 2015, Li et al., 2015, Nikalayevich and Ohkura, 2015, Stoiber et al., 2015, Bonnay et al., 2014, Lee et al., 2014, Lim et al., 2014, Matzat and Lei, 2014, Moy et al., 2014, Kwon et al., 2013, Kwon et al., 2013, Le Thomas et al., 2013, Taliaferro et al., 2013, Thomae et al., 2013, Xiong et al., 2013, Bolukbasi et al., 2012, Japanese National Institute of Genetics, 2012.5.21, Rodriguez et al., 2012, Baxley et al., 2011, Boeke et al., 2011, Franco et al., 2011, Friedman et al., 2011, Hartmann et al., 2011, Moshkovich et al., 2011, Qurashi et al., 2011, Kallappagoudar et al., 2010, Lamiable et al., 2010, Schneiderman et al., 2010, Ulvila et al., 2010, Ahlander and Bosco, 2009, Herold et al., 2009, Hurt et al., 2009, Obbard et al., 2009, Shpargel et al., 2009, Telonis-Scott et al., 2009, Chambeyron et al., 2008, Christensen et al., 2008.4.15, Fisher et al., 2008, Buszczak et al., 2007, Christensen et al., 2007.10.29, Christensen et al., 2007.10.29, Lei, 2007, Olson et al., 2007, Quinones-Coello, 2007, Robida et al., 2007, Dorner et al., 2006, Gresens and Cook, 2006.12.5, Lei and Corces, 2006, McIntyre et al., 2006, Loop et al., 2004)
            dmP68
            (Monzo et al., 2006)
            l(3)01086
            l(3)j3D2
            l(3)j3D5
            l(3)rG338
            l(3)s5196
            p68
            (Lee et al., 2018, Olson et al., 2007, Buszczak and Spradling, 2006, Matzke and Birchler, 2005)
            rm62
            (Cziko et al., 2009, Sofola et al., 2007)
            Name Synonyms
            Helicase p62
            (Sabath et al., 2013)
            Lighten up
            Lighten-up
            (Buszczak and Spradling, 2006)
            Rm62
            (Cammarato et al., 2011)
            Secondary FlyBase IDs
            • FBgn0010736
            • FBgn0011038
            • FBgn0011355
            • FBgn0011356
            • FBgn0011496
            • FBgn0011645
            Datasets (0)
            Study focus (0)
            Experimental Role
            Project
            Project Type
            Title
            References (184)