rhomboid-3, rho-3, rho3, rhomboid 3, rhomboid3
intra-membrane serine protease localized in the endoplasmic reticulum - Rhomboid and Roughoid/Rhomboid-3 act together on an unknown Egf to control cell recruitment through the Epidermal growth factor receptor most notably the eye
Gene model reviewed during 5.42
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.52
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\ru using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\ru in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: ru rhomboid-3 CG1214
ru, expressed in the ventral nerve cord, is necessary for repulsion of ganglionic tracheal branches from the ventral midline.
The abnormal ru phenotype is due to a developmental defect: late occurring defects. Adult eyes rough and reduced, with photoreceptor and pigment cell defects, eye disc pattern appears normal.