ANT, jive, A/A-T/sesB, ses B, Adenine nucleotide translocase
Please see the JBrowse view of Dmel\sesB for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.55
Gene model reviewed during 5.46
Shares 5' UTR with downstream gene.
Gene model reviewed during 5.56
1.6, 1.2 (northern blot)
1.85, 1.1 (northern blot)
299 (aa)
297 (aa)
The transmembrane helices are not perpendicular to the plane of the membrane, but cross the membrane at an angle. Odd-numbered transmembrane helices exhibit a sharp kink, due to the presence of a conserved proline residue.
Monomer.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\sesB using the Feature Mapper tool.
Comment: maternally deposited
sesB transcripts are detected in adult RNA on northern blots.
Both sesB transcripts are detected in RNA from Kc cells and 8-24 hr embryos.
sesB localizes to mitochondria in Malpighian tubule principal cells.
GBrowse - Visual display of RNA-Seq signals
View Dmel\sesB in GBrowse 2Mapped by Homyk.
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
Source for identity of: sesB CG16944
Source for identity of: sesB orangi
Source for merge of: sesB anon-WO02059370.55
Source for merge of sesB anon-WO02059370.55 was sequence comparison ( date:051113 ).
"l(1)G0083" may affect "Ant2" and/or "sesB".
Lack of complementation of lethal alleles and sesB alleles reported by Zhimulev et al. (FBrf0045718). Janca et al. (FBrf0044450) report lack of full complementation between sesB3 and sesB alleles.
sesB is a negative regulator of starvation-induced autophagic flux during oogenesis.
Identification: as a modifier of a temperature-sensitive paralytic mutation of shi.
Encodes the Adenine nucleotide (ADP/ATP) translocase of the inner mitochondrial membrane.
Most mutant alleles are lethal, but some show a stress-sensitive paralytic phenotype.
Claimed that Hmr encodes the adenine nucleotide translocase, but this is in error.
Homyk.