FlyBase Gene Report: Dmel\elA

General Information

Symbol

Dmel\elA

Species

D. melanogaster

Name

elbow A

Annotation Symbol

Feature Type

gene

FlyBase ID

FBgn0004857

Gene Model Status

Unannotated

Stock Availability

7 publicly available

Gene Summary

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Red Book
Interactive Fly

Also Known As

el, elbow

Function

Gene Ontology (GO) Annotations (0 terms)

Molecular Function (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Biological Process (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Cellular Component (0 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Gene Group (FlyBase)

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Phenotypic Description (Red Book; Lindsley and Zimm 1992)

el: elbow (M. Ashburner)

el: elbow

From Bridges and Brehme, 1944, Carnegie Inst. Washington Publ. No. 552: 75.

Wings extended and bent backward, often warped and shortened; sometimes blistered and nicked. Alulae reduced in size with reduced number of marginal bristles-may fuse with wing blade. Venation reduced by terminal shortening of L5 and of crossveins. Halteres reduced, often to stubs. Eye size decreased (variable, even with strong alleles). Weak alleles may overlap wild type and show only a reduction in number of marginal bristles on alulae. Some alleles may be semilethal when hemizygous. Class (i) alleles enhance Sco, are semilethal with alleles of l(2)35Ba and show a weak noc phenotype when heterozygous with strong noc alleles or noc deletions. Class (ii) alleles do not interact with these loci. All alleles more extreme when hemizygous; strong alleles nearly apterous.

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Transcript Data

Annotated Transcripts

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Polypeptides with Identical Sequences

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\elA using the Feature Mapper tool.

External Data

Crossreferences

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

NA

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\elA in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\elA

View exonic expression by tissue for Dmel\elA

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 16 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 0 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of elA

Transgenic constructs containing regulatory region of elA

Aberrations (Deficiencies and Duplications) ( 177 )

Inferred from experimentation ( 177 )

Gene disrupted in

Df(2L)64j

(Woodruff and Ashburner, 1979, Woodruff and Ashburner, 1979, O'Donnell et al., 1977)

Df(2L)A47

(Roote et al., 1996, Fossett et al., 1994, Gubb et al., 1990, Ashburner et al., 1982)

Df(2L)A215

(Fossett et al., 1994, Ashburner et al., 1982)

Df(2L)A217

(Fossett et al., 1994, Ashburner et al., 1982)

Df(2L)A246

(Fossett et al., 1994, Ashburner et al., 1982)

Df(2L)A263

(Ashburner et al., 1982)

Df(2L)A337

(Fossett et al., 1994)

Df(2L)A376

(Fossett et al., 1994, Ashburner et al., 1982)

Df(2L)A377

(Ashburner et al., 1982)

Df(2L)A400

(Davis et al., 1997, Roote et al., 1996, Fossett et al., 1994, Davis et al., 1990, Ashburner et al., 1982, Ashburner et al., 1982)

Df(2L)Adh-nBR100

(Fossett et al., 1994)

Df(2L)Adh-nBR101

(Fossett et al., 1994)

Df(2L)Adh-nBR103

(Fossett et al., 1994)

Df(2L)Adh-nBR117

(Fossett et al., 1994)

Df(2L)Adh-nBR120

(Fossett et al., 1994)

Df(2L)Adh-nBR125

(Fossett et al., 1994)

Df(2L)Adh-nBR130

(Fossett et al., 1994)

Df(2L)Adh-nBR131

(Fossett et al., 1994)

Df(2L)ARR1

(Roote, 1996.8, Roote et al., 1996, Davis et al., 1990)

Df(2L)b81a1

(Roote et al., 1996, Ashburner et al., 1982)

Df(2L)b84a2

(Davis et al., 1997, Roote et al., 1996, Davis et al., 1990)

Df(2L)b84a4

(Roote et al., 1996)

Df(2L)BSC300

(Christensen and Cook, 2008.4.15)

Df(2L)el14

(Davis et al., 1997, Roote et al., 1996, Davis et al., 1990)

Df(2L)el16

(Davis et al., 1997, Roote et al., 1996, Davis et al., 1990)

Df(2L)el28

(Davis et al., 1997, Roote et al., 1996)

Df(2L)el77

(Woodruff and Ashburner, 1979, Woodruff and Ashburner, 1979)

Df(2L)el80f1

(Ashburner et al., 1983)

Df(2L)el94

(Roote, 1996.9.18)

Df(2L)fn1

(Grau et al., 1984, Ashburner et al., 1982, Ashburner et al., 1982, Woodruff and Ashburner, 1979, Woodruff and Ashburner, 1979, O'Donnell et al., 1977)

Df(2L)fn2

(Davis et al., 1997, Roote et al., 1996, Ashburner et al., 1982, Ashburner et al., 1982, Woodruff and Ashburner, 1979, Woodruff and Ashburner, 1979, O'Donnell et al., 1977)

Df(2L)fn5

(Ashburner et al., 1982, O'Donnell et al., 1977)

Df(2L)fn7

(Ashburner et al., 1982, Woodruff and Ashburner, 1979, Woodruff and Ashburner, 1979, O'Donnell et al., 1977)

Df(2L)fn12

(Ashburner et al., 1982, Woodruff and Ashburner, 1979, O'Donnell et al., 1977)

Df(2L)fn15

(Roote, 1996.1.11, Roote, 1996.8, Ashburner et al., 1982, O'Donnell et al., 1977)

Df(2L)fn26

(Ashburner et al., 1982, O'Donnell et al., 1977)

Df(2L)fn30

(Ashburner et al., 1982, O'Donnell et al., 1977)

Df(2L)fn31

(Ashburner et al., 1982, O'Donnell et al., 1977)

Df(2L)fn36

(Ashburner et al., 1982, O'Donnell et al., 1977)

Df(2L)GT4

(Gubb et al., 1990)

Df(2L)GT5

(Gubb et al., 1990)

Df(2L)Sco7

(Ashburner et al., 1983)

Df(2L)Sco^rv23

(Grau et al., 1984, Ashburner et al., 1983)

Df(2L)TE35B-1

(Davis et al., 1997, Roote et al., 1996, Gubb et al., 1985)

Df(2L)TE35B-2

(Gubb et al., 1985)

Df(2L)TE35B-3

(Gubb et al., 1985)

Df(2L)TE35B-4

(Gubb et al., 1985)

Df(2L)TE35B-5

(Gubb et al., 1985)

Df(2L)TE35B-6

(Davis et al., 1997, Roote et al., 1996, Gubb et al., 1985)

Df(2L)TE35B-7

(Davis et al., 1997, Roote et al., 1996, Davis et al., 1990, Gubb et al., 1985)

Df(2L)TE35B-8

(Roote et al., 1996, Gubb et al., 1985)

Df(2L)TE35B-9

(Gubb et al., 1985)

Df(2L)TE35B-10

(Gubb et al., 1985)

Df(2L)TE35B-12

(Davis et al., 1997, Roote et al., 1996, Gubb et al., 1985)

Df(2L)TE35B-15

(Gubb et al., 1985)

Df(2L)TE35B-300

(Roote et al., 1996)

Df(2L)TE35BC-6

(Gubb et al., 1984)

Df(2L)TE35BC-8

(Davis et al., 1997, Roote et al., 1996, Davis et al., 1990, Gubb et al., 1984)

Df(2L)TE35BC-23

(Gubb et al., 1984)

Df(2L)TE35BC-29

(Gubb et al., 1984)

Df(2L)TE35BC-31

(Gubb et al., 1984)

Df(2L)W

(Ashburner et al., 1982, Woodruff and Ashburner, 1979, Woodruff and Ashburner, 1979)

Dp(2;2)Cam12

(Gubb et al., 1997, Roote et al., 1996, Roote, 1995.3.27)

In(2L)75c^LC158.1^R

(Woodruff and Ashburner, 1979, Woodruff and Ashburner, 1979)

In(2L)75c

(Grau et al., 1984, Woodruff and Ashburner, 1979, Woodruff and Ashburner, 1979)

In(2L)el94

(Roote, 1998.3.17)

In(2L)TE35B-13

(Gubb et al., 1985)

In(2LR)D20^Lnoc^4R

(Roote et al., 1996)

In(2LR)el⁶

(Roote et al., 1996)

In(2LR)el^6LA379^R

(Roote et al., 1996)

T(2;3)el24

(Davis et al., 1997)

T(Y;2)A80^DR15^P

(Woodruff and Ashburner, 1979, Woodruff and Ashburner, 1979)

Ts(2Lt;3Lt)dpp^s19+Ts(2Rt;3Rt)el24

(Roote, 1996.1.11, Roote, 1996.8, Roote et al., 1996, Roote, 1995.3.27)

Ts(2Lt;3Rt)GT10+Ts(2Rt;3Lt)TE35B-209

(Roote et al., 1996)

Ts(Y;2Lt)el⁴+Ts(YSt;2Rt)R15

(Davis et al., 1997, Roote et al., 1996, Ashburner et al., 1982)

Ts(YLt;2Lt)A80+Ts(Y;2Rt)TE35B-18

(Roote et al., 1996, Roote, 1995.3.27)

Ts(YLt;2Lt)G74+Ts(YSt;2Rt)B210

(Woodruff and Ashburner, 1979)

Ts(YSt;2Lt)G74+Ts(YSt;2Rt)J165

(Woodruff and Ashburner, 1979)

Ts(YSt;2Lt)G74+Ts(YSt;2Rt)P58

(Woodruff and Ashburner, 1979)

Ts(YSt;2Lt)G74+Ts(YSt;2Rt)R15

(Woodruff and Ashburner, 1979)

Gene not disrupted in

Df(2L)A48

(Roote et al., 1996, Fossett et al., 1994, Gubb et al., 1990, Grau et al., 1984, Ashburner et al., 1982, Ashburner et al., 1982)

Df(2L)A63

(Roote et al., 1996, Fossett et al., 1994, Ashburner et al., 1982, Ashburner et al., 1982)

Df(2L)A72

(Fossett et al., 1994, Ashburner et al., 1982, Ashburner et al., 1982)

Df(2L)A178

(Davis et al., 1997, Roote et al., 1996, Fossett et al., 1994, Ashburner et al., 1982, Ashburner et al., 1982)

Df(2L)A220

(Fossett et al., 1994, Ashburner et al., 1982)

Df(2L)A245

(Roote et al., 1996, Fossett et al., 1994, Davis et al., 1990, Ashburner et al., 1982)

Df(2L)A260

(Davis et al., 1990, Ashburner et al., 1982)

Df(2L)A264

(Fossett et al., 1994, Ashburner et al., 1982)

Df(2L)A266

(Fossett et al., 1994, Davis et al., 1990, Ashburner et al., 1982, Ashburner et al., 1982)

Df(2L)A267

(Roote et al., 1996, Fossett et al., 1994, Ashburner et al., 1982, Ashburner et al., 1982)

Df(2L)A379

(Fossett et al., 1994, Ashburner et al., 1982, Ashburner et al., 1982)

Df(2L)A445

(Roote et al., 1996, Fossett et al., 1994, Ashburner et al., 1982)

Df(2L)Adh-nBR102

(Roote, 1996.1.11, Roote, 1996.8, Roote et al., 1996, Fossett et al., 1994)

Df(2L)Adh-nBR105

(Fossett et al., 1994)

Df(2L)Adh-nBR106

(Roote, 1996.1.11, Roote, 1996.8, Fossett et al., 1994)

Df(2L)Adh-nBR107

(Fossett et al., 1994)

Df(2L)Adh-nBR118

(Roote, 1996.1.11, Roote, 1996.8, Fossett et al., 1994)

Df(2L)Adh-nBR119

(Roote, 1996.1.11, Roote, 1996.8, Fossett et al., 1994)

Df(2L)Adh-nBR121

(Fossett et al., 1994)

Df(2L)Adh-nBR122

(Fossett et al., 1994)

Df(2L)Adh-nBR126

(Roote, 1996.1.11, Roote, 1996.8, Fossett et al., 1994)

Df(2L)Adh-nBR127

(Fossett et al., 1994)

Df(2L)Adh-nBR128

(Fossett et al., 1994)

Df(2L)Adh-nBR129

(Roote, 1996.1.11, Roote, 1996.8, Fossett et al., 1994)

Df(2L)b75

(Gubb et al., 1990, Woodruff and Ashburner, 1979, Woodruff and Ashburner, 1979)

Df(2L)b80e3

(Roote et al., 1996, Ashburner et al., 1982)

Df(2L)b81a2^LA80^R

(Roote, 2000.7.3)

Df(2L)b83d29a

(Roote, 2000.7.3, Davis et al., 1997, Roote et al., 1996, Davis et al., 1990)

Df(2L)b88h49

(Roote et al., 1996)

Df(2L)ED3

(Ryder and Roote, 2004.11.10, Ryder et al., 2004, Roote, 2002.2.6)

Df(2L)el28

(Davis et al., 1990)

Df(2L)fn3

(Davis et al., 1997, Davis et al., 1990, Ashburner et al., 1982, Woodruff and Ashburner, 1979, Woodruff and Ashburner, 1979, O'Donnell et al., 1977)

Df(2L)fn27

(Davis et al., 1997, Ashburner et al., 1982, Ashburner et al., 1982, O'Donnell et al., 1977)

Df(2L)n78l3

(Davis et al., 1997, Ashburner et al., 1982)

Df(2L)nNxF1

(Roote, 1996.8)

Df(2L)osp29

(Roote et al., 1996, Grau et al., 1984, Ashburner et al., 1982)

Df(2L)osp144

(Roote, 1996.8, Roote et al., 1996, Ashburner et al., 1982)

Df(2L)PA4

(Ashburner et al., 1983)

Df(2L)Sco^rv4

(Ashburner et al., 1990, Ashburner et al., 1983)

Df(2L)Sco^rv10

(Grau et al., 1984, Ashburner et al., 1983, Woodruff and Ashburner, 1979)

Df(2L)Sco^rv14

(Ashburner et al., 1983, Woodruff and Ashburner, 1979)

Df(2L)Sco^rv16

(Grau et al., 1984, Ashburner et al., 1983)

Df(2L)Sco^rv18

(Ashburner et al., 1983)

Df(2L)Sco^rv19

(Grau et al., 1984, Ashburner et al., 1983)

Df(2L)Sco^rv25

(Grau et al., 1984, Ashburner et al., 1983)

Df(2L)SS1

(Grau et al., 1984)

Df(2L)TE35B-1

(Davis et al., 1990)

Df(2L)TE35B-6

(Davis et al., 1990)

Df(2L)TE35B-11

(Roote et al., 1996, Gubb et al., 1985)

Df(2L)TE35B-54^L

(Roote, 1996.8, Roote et al., 1996)

Df(2L)TE35BC-1

(Gubb et al., 1984)

Df(2L)TE35BC-3

(Grau et al., 1984, Gubb et al., 1984, Ashburner et al., 1982)

Df(2L)TE35BC-4

(Roote et al., 1996, Gubb et al., 1984, Ashburner et al., 1982)

Df(2L)TE35BC-7

(Gubb et al., 1984)

Df(2L)TE35BC-24

(Gubb et al., 1984)

Df(2L)TE35BC-28

(Gubb et al., 1984)

Df(2L)TE35BC-34

(Gubb et al., 1984)

Df(2L)TE35BC-35

(Gubb et al., 1984)

In(2L)C158^LSco^rv11R

(Ashburner and Harrington, 1984, Ashburner et al., 1983)

In(2L)C158^LSco^rv17R

(Ashburner and Harrington, 1984, Ashburner et al., 1983)

In(2L)el⁹

(Davis et al., 1990)

In(2LR)DTD128

(Roote et al., 1996, Davis et al., 1990)

In(2LR)el⁶

(Davis et al., 1990)

In(2LR)noc^4LSco^rv9R

(Ashburner and Harrington, 1984)

In(2LR)TE35B-6^LSco^rv9R

(Ashburner and Harrington, 1984)

T(2;3)dpp^s19

(Davis et al., 1990)

T(2;3)el24

(Roote et al., 1996, Davis et al., 1990)

T(2;3)GT8

(Davis et al., 1990)

T(2;3)GT10

(Davis et al., 1990)

T(2;3)Sco^rv7

(Ashburner and Harrington, 1984, Grau et al., 1984, Ashburner et al., 1983, Woodruff and Ashburner, 1979)

T(2;3)TE35B-2a

(Chia et al., 1985)

T(2;3)TE35B-3^DG16^P

(Chia et al., 1985)

T(Y;2)a15

(Davis et al., 1990)

T(Y;2)A80^DR15^P

(Ashburner et al., 1982)

T(Y;2)A80

(Roote et al., 1996, Davis et al., 1990)

T(Y;2)el⁴

(Davis et al., 1990)

T(Y;2)GT2

(Davis et al., 1990)

T(Y;2)J165^DP58^P

(Woodruff and Ashburner, 1979, Woodruff and Ashburner, 1979)

T(Y;2)R15^DJ165^P

(Woodruff and Ashburner, 1979, Woodruff and Ashburner, 1979)

T(Y;2)TE35B-18

(Roote et al., 1996)

Tp(2;2)A446

(Davis et al., 1997, Roote et al., 1996, Fossett et al., 1994, Ashburner et al., 1982, Ashburner et al., 1982)

Tp(2;3)GT3

(Davis et al., 1990)

Ts(2Lt;3Lt)Mpe+Ts(2Rt;3Rt)G16

(Chia et al., 1985)

Ts(2Lt;3Lt)TE35B-4+Ts(2Rt;3Rt)Sco^rv13

(Chia et al., 1985, Ashburner and Harrington, 1984)

Ts(2Lt;3Lt)TE35B-28+Ts(2Rt;3Rt)osp⁹⁰

(Roote et al., 1996)

Ts(2Lt;3Lt)TE35BC-3+Ts(2Rt;3Rt)Sco^rv13

(Ashburner and Harrington, 1984, Ashburner et al., 1983)

Ts(Y;2Lt)a15+Ts(YSt;2Rt)A80

(Roote, 1996.1.11, Roote, 1996.8)

Ts(Y;2Lt)el⁴+Ts(YSt;2Rt)A80

(Roote, 1996.1.11, Roote, 1996.8, Roote et al., 1996)

Ts(Y;2Lt)GT2+Ts(YSt;2Rt)A80

(Roote, 1996.1.11, Roote, 1996.8, Roote et al., 1996)

Ts(Y;2Lt)TE35B-18+Ts(YSt;2Rt)R15

(Davis et al., 1990)

Ts(YSt;2Lt)G74+Ts(YSt;2Rt)A80

(Woodruff and Ashburner, 1979)

Gene duplicated in

Dp(2;1)Sco^rv23

(Grau et al., 1984, Ashburner et al., 1983, Ashburner et al., 1981)

In(2LR)TE35B-226^LDTD128^R

(Roote et al., 1996)

Ts(2Lt;4Lt)TE35B-101+Ts(2Rt;4Rt)GT6

(Roote et al., 1996)

Ts(Y;2Lt)TE35B-18+Ts(YSt;2Rt)A80

(Roote et al., 1996)

Ts(YLt;2Lt)R15+Ts(Y;2Rt)el⁴

(Roote et al., 1996)

Ts(YLt;2Lt)R15+Ts(YSt;2Rt)A80

(Roote et al., 1996)

Gene not duplicated in

Dp(2;2)TE35B-54^L

(Roote et al., 1996)

Dp(2;3)osp³

(Roote et al., 1996)

In(2L)C163.41^LC158^R

(Roote et al., 1996)

Ts(YLt;2Lt)A80+Ts(Y;2Rt)el⁴

(Roote et al., 1996)

Ts(YLt;2Lt)A80+Ts(YLt;2Rt)G74

(Roote et al., 1996)

Ts(YLt;2Lt)R15+Ts(Y;2Rt)TE35B-18

(Roote et al., 1996)

Inferred from location ( 0 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable

elA¹

Other Phenotypes

Allele

visible

elA¹

visible | recessive

elA²⁴

Phenotype manifest in

Allele

alar lobe

elA¹

costal wing cell

elA¹

dorsal row of wing sensilla

elA¹

haltere

elA²⁴

wing

wing | posterior

elA²⁴

wing vein L1

elA¹

wing vein L4

elA¹

wing vein L5

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (0)

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (0)

Mus musculus (laboratory mouse) (0)

Xenopus tropicalis (Western clawed frog) (0)

Danio rerio (Zebrafish) (0)

Caenorhabditis elegans (Nematode, roundworm) (0)

Anopheles gambiae (African malaria mosquito) (0)

Arabidopsis thaliana (thale-cress) (0)

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (0)

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:elA. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (0)

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

sna

enhanceable

elA

(Davis et al., 1997)

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0004857

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Class of Gene

gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

Cytogenetic map

35B1-35B1

Sequence location

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

35B1-35B1

Left limit from inclusion within Df(2L)fn15 (FBrf0030161) Right limit from complementation mapping against Ts(Y;2Lt)TE35B-18+Ts(YSt;2Rt)A80 (FBrf0091422)

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

35B1-35B2

(determined by in situ hybridisation)

(Davis et al., 1990)

Experimentally Determined Recombination Data

Location

2-50.0

(Lindsley and Zimm, 1992)

2-49.9 +/- 0.1

(O'Donnell et al., 1977)

Left of (cM)

Adh
PolD3

(Woodruff and Ashburner, 1979)

Right of (cM)

(Woodruff and Ashburner, 1979)

Notes

Stocks and Reagents

Stocks (7)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

289

Adc^b-1 elA¹ PolD3^rd-s pr¹ cn¹ or^49h

1022

Adc^b-1 elA¹ PolD3^rd-s Mhc⁵ pr¹ Bl¹/CyO

3593

Adc^b-1 Orc5² elA¹ PolD3^rd-s pr¹ cn¹/CyO

5376

Adc^b-1 elA¹ PolD3^rd-s cub² pr¹ cn¹/CyO, P{en1}wg^en11

Kyoto

105837

Adc^b-1 elA¹ PolD3^rd-s pr¹ cn¹ or^49h

106170

Adc^b-1 elA¹ PolD3^rd-s Mhc⁵ pr¹ Bl¹/CyO

107117

Adc^b-1 Orc5² elA¹ PolD3^rd-s pr¹ cn¹/CyO

Genomic Clones (0)

cDNA Clones (0)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

The elbow locus is made up of two genes, elA and elB, each of which has a distinct phenotype when mutant. Mutations in elA have a strong phenotype with marked disruptions of the wing. Mutations in elB are weak, mainly affecting the alula and wing bristles. elA and elB are dominant enhancers of each other.

(Davis et al., 1997)

Part of the "elbow-noc" complex.

(Lindsley and Zimm, 1992)

Wings extended and bent backward, often warped and shortened; sometimes blistered and nicked. Alulae reduced in size with reduced number of marginal bristles -- may fuse with wing blade. Venation reduced by terminal shortening of L5 and of crossveins. Halteres reduced, often to stubs. Eye size decreased (variable, even with strong alleles). Weak alleles may overlap wild type and show only a reduction in number of marginal bristles on alulae. Some alleles may be semi-lethal when hemizygous. Class (i) alleles enhance noc^Sco, are semi-lethal with 35Ba alleles of noc and show a weak noc phenotype when heterozygous with strong noc alleles or noc deletions. Class (ii) alleles do not interact with these loci. All alleles more extreme when hemizygous; strong alleles nearly apterous.

(Lindsley and Zimm, 1992)

Relationship to Other Genes

Source for database merge of

Additional comments

"elA" may correspond to "CG15283".

(Davis, 2003)

May correspond to CG15283 locus.

(Davis, 2003.5.6)

" BG:DS08340.1 " is probably "elA".

(Ashburner et al., 1999)

" BG:DS08340.1 " probably corresponds to "elA".

(Ashburner et al., 1999.10.12)

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

Name Synonyms

elbow

(Luque and Milan, 2007, Culi et al., 2006, Ghabrial et al., 2003, Palsson and Gibson, 2000, Greaves et al., 1999, Fossett et al., 1994)

elbow A

Secondary FlyBase IDs

FBgn0000569

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 1 )

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0004857

References (55)

NA

Report Sections