E78, E78B, E78A, nuclear hormone receptor, NR1E1
Gene model reviewed during 5.40
Unconventional translation start (CUG) postulated; FBrf0064719
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.46
4.8, 4.3, 4.1, 4.0, 3.5, 3.2, 2.6 (northern blot)
864, 390 (aa); 95.9, 43.8 (kD)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Eip78C using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Eip78C in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Eip78C is required to establish the somatic germline stem cell niche in the ovary and it functions in the germline to promote the survival of developing follicles.
Gene expression is increased in response to the presence of two copies of Scer\GAL4hs.PB.
RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.
Normal Eip78C gene function is not required for viability or fertility, and its disruption has no visible phenotype. Deletion and overexpression of Eip78C demonstrates it function is required for the maximal induction of a subset of late puffs.
This ecdysone inducible gene encodes two nested transcription units. The larger encodes a member of the nuclear hormone receptor superfamily, the smaller encodes a truncated version that lacks the DNA binding domain.