FlyBase Gene Report: Dmel\Arf1

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 4 -- 6

(Fisher et al., 2012)

embryonic stage 7 -- 8

(Fisher et al., 2012)

embryonic stage 9 -- 10

(Fisher et al., 2012)

embryonic stage 11 -- 12

embryonic/larval lymph gland

(Fisher et al., 2012)

embryonic stage 13 -- 16

organism | ubiquitous

(Fisher et al., 2012)

northern blot

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

(Murtagh et al., 1993)

Additional Descriptive Data

Arf1 transcripts are detected in RNA isolated from adult heads, legs and bodies. The highest levels are in legs and the lowest levels in heads.

(Murtagh et al., 1993)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

larval stage

(Khadilkar et al., 2014)

embryonic/larval hemocyte

(Khadilkar et al., 2014)

adult stage

hemocyte

(Khadilkar et al., 2014)

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

day 7 of adulthood -- day 49 of adulthood

adult heart

(Cammarato et al., 2011)

Additional Descriptive Data

Arf1 protein is expressed in all larval and adult blood cell types, and colocalizes with endosomal, Golgi, and lysosomal markers. Arf1 protein expression overlaps with that of asrij.

(Khadilkar et al., 2014)

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in apical part of cell

inferred from direct assay

(Shao et al., 2010)

located_in cleavage furrow

inferred from direct assay

(Lee et al., 2015)

located_in cytoplasm

inferred from direct assay

(Shao et al., 2010)

located_in endosome

inferred from direct assay

(Khadilkar et al., 2014)

located_in Golgi apparatus

inferred from direct assay

(Wang et al., 2017, Lee et al., 2015, Khadilkar et al., 2014)

inferred from direct assay

(Rodrigues et al., 2016)

located_in Golgi stack

inferred from direct assay

(Armbruster and Luschnig, 2012)

located_in lysosome

inferred from direct assay

(Khadilkar et al., 2014)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Arf1 in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Arf1

View exonic expression by tissue for Dmel\Arf1

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0010348

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

40506/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0010348

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0010348

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0010348

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG8385

Flygut - An atlas of the Drosophila adult midgut

FBgn0010348

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 13 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 22 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Arf1

Transgenic constructs containing regulatory region of Arf1

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation ( 1 )

Gene disrupted in

Df(3L)Exel6139

(Ryder, 2004.4.26)

Inferred from location ( 5 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal, with Scer\GAL4^Act.PU

Arf1^NIG.8385R

lethal, with Scer\GAL4^pnr-MD237

Arf1^GD12522

lethal - all die before end of larval stage, with Scer\GAL4^en-e16E

Arf1^T31N.UAS

lethal - all die during P-stage, with Scer\GAL4^Mef2.PR

Arf1^GD12522

partially lethal, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Arf1^GD12522

viable

Arf1^EY08473

viable, with Scer\GAL4^tin.CΔ4

Arf1^GD12522

Sterility

Allele

fertile

Arf1^EY08473

Other Phenotypes

Allele

abnormal cell shape | embryonic stage, with Scer\GAL4^en-e16E

Arf1^T31N.UAS

abnormal immune response | adult stage, with Scer\GAL4^btl.PS

Arf1^GD12522

abnormal immune response | adult stage, with Scer\GAL4^e33C

Arf1^GD12522

abnormal immune response | adult stage, with Scer\GAL4^Hml.PU

Arf1^GD12522

abnormal neuroanatomy | pupal stage, with Scer\GAL4^ppk.PU

abnormal neuroanatomy | pupal stage | RU486 conditional, with Scer\GAL4^GSG2295

increased occurrence of cell division | third instar larval stage, with Scer\GAL4^e33C

Arf1^GD12522

short lived, with Scer\GAL4^btl.PS

Arf1^GD12522

Phenotype manifest in

Allele

cleavage furrow | embryonic stage | maternal effect, with Scer\GAL4^{VP16.mat.αTub67C}

Arf1^RNAi.4.UASp

cortical zone of lymph gland primary lobe | third instar larval stage, with Scer\GAL4^e33C

Arf1^GD12522

dendritic tree | pupal stage, with Scer\GAL4^ppk.PU

dendritic tree | pupal stage | RU486 conditional, with Scer\GAL4^GSG2295

dendritic tree | pupal stage | somatic clone, with Scer\GAL4^109(2)80

Arf1^T31N.UAS.cWa

embryonic/larval crystal cell | third instar larval stage, with Scer\GAL4^dome-PG14

Arf1^GD12522

embryonic/larval crystal cell | third instar larval stage, with Scer\GAL4^e33C

Arf1^GD12522

embryonic/larval crystal cell | third instar larval stage, with Scer\GAL4^gcm.PU

Arf1^GD12522

embryonic/larval crystal cell | third instar larval stage, with Scer\GAL4^Hml.Δ

Arf1^GD12522

embryonic/larval crystal cell | third instar larval stage, with Scer\GAL4^{kn-col85-GAL4}

embryonic/larval crystal cell | third instar larval stage, with Scer\GAL4^Pxn.PS

Arf1^GD12522

embryonic/larval hemocyte, with Scer\GAL4^gcm.PU

Arf1^GD12522

embryonic/larval hemocyte | second instar larval stage, with Scer\GAL4^e33C

Arf1^GD12522

embryonic/larval hemocyte | third instar larval stage, with Scer\GAL4^e33C

Arf1^GD12522

embryonic/larval plasmatocyte | third instar larval stage, with Scer\GAL4^dome-PG14

Arf1^GD12522

embryonic/larval plasmatocyte | third instar larval stage, with Scer\GAL4^e33C

Arf1^GD12522

embryonic/larval plasmatocyte | third instar larval stage, with Scer\GAL4^gcm.PU

Arf1^GD12522

embryonic/larval plasmatocyte | third instar larval stage, with Scer\GAL4^Hml.Δ

Arf1^GD12522

embryonic/larval plasmatocyte | third instar larval stage, with Scer\GAL4^{kn-col85-GAL4}

embryonic/larval plasmatocyte | third instar larval stage, with Scer\GAL4^Pxn.PS

Arf1^GD12522

embryonic epidermis, with Scer\GAL4^en-e16E

Arf1^T31N.UAS

embryonic myoblast, with Scer\GAL4^Mef2.PR

Arf1^T31N.UAS

exocyst | third instar larval stage, with Scer\GAL4^ppk.PU

Arf1^GD12522

eye, with Scer\GAL4^ey.PU

Arf1^NIG.8385R

eye, with Scer\GAL4^GMR.PU

Arf1^NIG.8385R

Golgi apparatus | third instar larval stage, with Scer\GAL4^ppk.PU

Arf1^GD12522

Golgi apparatus | third instar larval stage | RU486 conditional, with Scer\GAL4^GSG2295

Arf1^T31N.UAS.cWa

hemocyte | third instar larval stage, with Scer\GAL4^srp.PU

Arf1^GD12522

lamellocyte, with Scer\GAL4^Pxn.PS

Arf1^GD12522

larval dorsal multidendritic neuron ddaC | pupal stage, with Scer\GAL4^ppk.PU

larval dorsal multidendritic neuron ddaC | pupal stage | RU486 conditional, with Scer\GAL4^GSG2295

larval dorsal multidendritic neuron ddaC | third instar larval stage, with Scer\GAL4^ppk.PU

Arf1^GD12522

larval dorsal multidendritic neuron ddaC | third instar larval stage | RU486 conditional, with Scer\GAL4^GSG2295

Arf1^T31N.UAS.cWa

larval dorsal multidendritic neuron ddaD | pupal stage | somatic clone, with Scer\GAL4^109(2)80

Arf1^T31N.UAS.cWa

larval dorsal multidendritic neuron ddaE | pupal stage | somatic clone, with Scer\GAL4^109(2)80

Arf1^T31N.UAS.cWa

ommatidium | adult stage, with Scer\GAL4^ninaE.PU

Arf1^CA.UAS.cUa

posterior signaling center of lymph gland primary lobe | first instar larval stage, with Scer\GAL4^{kn-col85-GAL4}

Arf1^GD12522

posterior signaling center of lymph gland primary lobe | second instar larval stage, with Scer\GAL4^{kn-col85-GAL4}

Arf1^GD12522

posterior signaling center of lymph gland primary lobe | third instar larval stage, with Scer\GAL4^e33C

Arf1^GD12522

posterior signaling center of lymph gland primary lobe | third instar larval stage, with Scer\GAL4^Hml.Δ

Arf1^GD12522

posterior signaling center of lymph gland primary lobe | third instar larval stage, with Scer\GAL4^{kn-col85-GAL4}

Arf1^GD12522

posterior signaling center of lymph gland primary lobe | third instar larval stage, with Scer\GAL4^Pxn.PS

Arf1^GD12522

rhabdomere | adult stage, with Scer\GAL4^ninaE.PU

Arf1^CA.UAS.cUa

rhabdomere R7, with Scer\GAL4^Rh3.PP

Arf1^GS10682

secondary lobe of embryonic/larval lymph gland | third instar larval stage, with Scer\GAL4^e33C

Arf1^GD12522

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (33)

Hsap\ARF1

14 of 14

Yes

Hsap\ARF3

11 of 14

Yes

5 of 14

5 of 14

4 of 14

4 of 14

Yes

Hsap\ARL17A

4 of 14

Yes

Hsap\ARL17B

4 of 14

Yes

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

Yes

Hsap\TRIM23

3 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

Yes

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (28)

Rnor\Arf1

13 of 14

Yes

Rnor\Arf2

10 of 14

Yes

Rnor\Arf3

9 of 14

Yes

5 of 14

5 of 14

4 of 14

4 of 14

Yes

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

Yes

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Rnor\Arl13b

1 of 14

Rnor\Arl16

1 of 14

Rnor\Srprb

1 of 14

Mus musculus (laboratory mouse) (29)

Mmus\Arf1

14 of 14

Yes

Mmus\Arf3

11 of 14

Yes

Mmus\Arf2

10 of 14

Yes

5 of 14

4 of 14

4 of 14

4 of 14

Yes

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

Yes

Mmus\Arl15

2 of 14

Mmus\Trim23

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (35)

Xtro\arf5

10 of 13

Yes

Xtro\ppp1r14c

9 of 13

Yes

Xtro\arf3

7 of 13

Xtro\arf1

6 of 13

Yes

3 of 13

3 of 13

3 of 13

2 of 13

2 of 13

2 of 13

Yes

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\arl13a

1 of 13

Yes

Xtro\arl13b

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\srprb

1 of 13

Xtro\trim23

1 of 13

Yes

Danio rerio (Zebrafish) (43)

Drer\arf2a

13 of 14

Yes

Drer\arf1

10 of 14

Yes

Drer\arf3a

10 of 14

Yes

Drer\arf3b

10 of 14

Yes

Drer\arf4a

6 of 14

Drer\arf4b

5 of 14

Yes

Drer\arf5

5 of 14

Drer\si:ch1073-165f9.2

5 of 14

Yes

5 of 14

4 of 14

4 of 14

4 of 14

Yes

Drer\zgc:110286

4 of 14

Yes

Drer\arf2b

3 of 14

Yes

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

Yes

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (14)

Cele\arf-1

14 of 14

Yes

Cele\arf-5

6 of 14

Cele\warf-1

5 of 14

Yes

Cele\arf-6

4 of 14

Cele\arc-1

3 of 14

Yes

3 of 14

3 of 14

3 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Anopheles gambiae (African malaria mosquito) (13)

Agam\AgaP_AGAP012014

11 of 12

Yes

4 of 12

4 of 12

4 of 12

3 of 12

2 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (25)

Atha\ARF1

12 of 13

Yes

Atha\ARFA1D

12 of 13

Yes

Atha\ARFA1E

12 of 13

Yes

Atha\ARFA1F

12 of 13

Yes

Atha\ARF1A1C

11 of 13

Yes

Atha\ARFA1B

11 of 13

Yes

Atha\ARFB1A

6 of 13

Yes

Atha\ARFB1B

4 of 13

Yes

Atha\ARFD1A

4 of 13

Yes

Atha\ARFD1B

4 of 13

Yes

Atha\ARFB1C

3 of 13

Yes

3 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (7)

Scer\ARF1

11 of 13

Yes

Scer\ARF2

11 of 13

Yes

3 of 13

2 of 13

1 of 13

1 of 13

1 of 13

Schizosaccharomyces pombe (Fission yeast) (4)

Spom\arf1

11 of 12

Yes

Spom\arf6

3 of 12

Spom\alp41

1 of 12

Spom\srp102

1 of 12

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:Arf1. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (15)

8 of 13

5 of 13

5 of 13

4 of 13

4 of 13

4 of 13

4 of 13

2 of 13

2 of 13

2 of 13

2 of 13

dnd

2 of 13

Sar1

2 of 13

CG11356

1 of 13

SrpRβ

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Allele

Disease

Interaction

References

Arf1^KK101396

ameliorates cancer

modeled by Delta^UAS.cDa, lola^GS88A8, psq^GS88A8

(Even et al., 2019)

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

ARF1; ARF GTPase 1

14 of 14

103180

PERIVENTRICULAR NODULAR HETEROTOPIA 8; PVNH8

11 of 14

5 of 14

5 of 14

4 of 14

ARL14; ARF like GTPase 14

4 of 14

614439

ARL17A; ARF like GTPase 17A

4 of 14

ARL17B; ARF like GTPase 17B

4 of 14

ARL1; ARF like GTPase 1

3 of 14

603425

ARL5A; ARF like GTPase 5A

3 of 14

608960

ARL5B; ARF like GTPase 5B

3 of 14

608909

ARL5C; ARF like GTPase 5C

3 of 14

ARL6; ARF like GTPase 6

3 of 14

608845

ARL11; ARF like GTPase 11

3 of 14

609351

Hsap\LOC100996709

3 of 14

TRIM23; tripartite motif containing 23

3 of 14

601747

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

Arf1 - AP-1-2β

(Christis and Munro, 2012)

Arf1 - AP-1γ

anti tag coimmunoprecipitation, Identification by mass spectrometry

(Christis and Munro, 2012)

Arf1 - Akt

(Vinayagam et al., 2016)

Arf1 - Arf4

(Guruharsha et al., 2011)

Arf1 - Arl8

(Guruharsha et al., 2011)

Arf1 - CCT3

(Guruharsha et al., 2011)

Arf1 - CCT6

(Guruharsha et al., 2011)

Arf1 - CG1416

(Guruharsha et al., 2011)

Arf1 - CG32219

(Guruharsha et al., 2011)

Arf1 - Chc

(Guruharsha et al., 2011)

Arf1 - CtsL1

(Guruharsha et al., 2011)

Arf1 - Cyfip

pull down, western blot

(Humphreys et al., 2012)

Arf1 - Gale

proximity ligation assay, fluorescence microscopy

(Guruharsha et al., 2011)

Arf1 - Git

(Portela et al., 2024)

Arf1 - Gmap

(Christis and Munro, 2012)

Arf1 - Gp93

(Guruharsha et al., 2011)

Arf1 - Hel25E

(Guruharsha et al., 2011)

Arf1 - Hem

pull down, western blot

(Humphreys et al., 2012)

Arf1 - Hsp83

(Guruharsha et al., 2011)

Arf1 - KdelR

(Guruharsha et al., 2011)

Arf1 - Ldh

(Guruharsha et al., 2011)

Arf1 - Mcad

(Guruharsha et al., 2011)

Arf1 - Mec2

(Guruharsha et al., 2011)

Arf1 - Ost1

(Guruharsha et al., 2011)

Arf1 - Ost48

(Guruharsha et al., 2011)

Arf1 - OstΔ

bimolecular fluorescence complementation, fluorescence microscopy, proximity-dependent biotin identification

(Guruharsha et al., 2011)

Arf1 - Patronin

(Gujar et al., 2023)

Arf1 - Rab1

(Guruharsha et al., 2011)

Arf1 - Rab11

(Guruharsha et al., 2011)

Arf1 - Rab2

anti tag coimmunoprecipitation, peptide massfingerprinting

(Guruharsha et al., 2011)

Arf1 - Rab23

(Çiçek et al., 2016)

Arf1 - Rab5

(Guruharsha et al., 2011)

Arf1 - Rab6

(Guruharsha et al., 2011)

Arf1 - Rdh1

(Guruharsha et al., 2011)

Arf1 - RpS15Ab

(Guruharsha et al., 2011)

Arf1 - Rpt1

anti tag coimmunoprecipitation, Identification by mass spectrometry

(Guruharsha et al., 2011)

Arf1 - S6k

(Vinayagam et al., 2016)

Arf1 - SERCA

(Guruharsha et al., 2011)

Arf1 - ScsβG

pull down, western blot, enzymatic study, fluorescence technology, anti tag coimmunoprecipitation, anti tag western blot

(Guruharsha et al., 2011)

Arf1 - Sec71

(Wang et al., 2017)

Arf1 - SsRβ

(Guruharsha et al., 2011)

Arf1 - Tapδ

(Guruharsha et al., 2011)

Arf1 - Tecr

(Guruharsha et al., 2011)

Arf1 - Tspo

(Guruharsha et al., 2011)

Arf1 - UQCR-C2

anti bait coimmunoprecipitation, western blot, proximity ligation assay, fluorescence microscopy, dihydrofolate reductase reconstruction

(Guruharsha et al., 2011)

Arf1 - asrij

(Motiwala et al., 2021, Khadilkar et al., 2014)

Arf1 - g

(Christis and Munro, 2012)

Arf1 - garz

proximity ligation assay, fluorescence microscopy, anti tag coimmunoprecipitation, peptide massfingerprinting, anti tag western blot

(Christis and Munro, 2012)

Arf1 - hpo

(Portela et al., 2024, Kwon et al., 2013, Kwon et al., 2013)

Arf1 - mEFTu1

(Guruharsha et al., 2011)

Arf1 - mge

bimolecular fluorescence complementation, fluorescence microscopy, proximity ligation assay

(Guruharsha et al., 2011)

Arf1 - msps

(Gujar et al., 2023)

Arf1 - ox

proximity ligation assay, fluorescence microscopy

(Guruharsha et al., 2011)

Arf1 - pix

(Portela et al., 2024)

Arf1 - porin

(Guruharsha et al., 2011)

Arf1 - rb

anti tag coimmunoprecipitation, Identification by mass spectrometry

(Christis and Munro, 2012)

Arf1 - rictor

(Vinayagam et al., 2016)

Arf1 - sav

anti tag coimmunoprecipitation, peptide massfingerprinting

(Kwon et al., 2013)

Arf1 - spidey

bimolecular fluorescence complementation, fluorescence microscopy, proximity ligation assay

(Guruharsha et al., 2011)

Arf1 - sqh

(Gujar et al., 2025)

Arf1 - vib

bimolecular fluorescence complementation, fluorescence microscopy, proximity ligation assay

(Gujar et al., 2025)

Arf1 - wal

(Guruharsha et al., 2011)

Arf1 - αCOP

(Christis and Munro, 2012)

Arf1 - β'COP

(Christis and Munro, 2012)

Arf1 - βCOP

(Christis and Munro, 2012)

Arf1 - βTub85D

(Guruharsha et al., 2011)

Arf1 - γCOP

(Christis and Munro, 2012)

Arf1 - δCOP

(Christis and Munro, 2012)

Summary of Genetic Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

suppressible

Nrg

(Wang et al., 2017)

suppressible

Pi3K92E

(Khadilkar et al., 2014)

suppressible

Pld

(Thakur et al., 2016)

Pi3K92E|Arf1

suppressible

Pten

(Khadilkar et al., 2014)

suppressible

Pvr

(Khadilkar et al., 2014)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Arf6

enhanceable

(Marcetteau et al., 2021)

arm

enhanceable

(Marcetteau et al., 2021)

baz

enhanceable

(Shao et al., 2010)

Delta|lola|psq

suppressible

(Even et al., 2019)

garz

enhanceable

(Armbruster and Luschnig, 2012)

Iqsec

suppressible

(Dottermusch-Heidel et al., 2012)

p120ctn

suppressible

(Greig and Bulgakova, 2020)

Pvr

suppressible

(Khadilkar et al., 2014)

Sec71

suppressible