Ror proteins are ROR proteins are a class of Wnt-binding receptor tyrosine kinases - expressed during neural differentiation - promotes dendrite regeneration as part of a Wnt signaling pathway that regulates dendritic microtubule nucleation
Gene model reviewed during 5.46
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Ror using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Ror in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Identified by PCR fragment; relationship to other protein tyrosine kinase genes not known.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Phylogenetic analysis of the PTK family.
cDNA encoding Ror identified by screening a late-third-instar larval brain library with a PCR-based approach designed to identify receptor tyrosine kinase-encoding genes: from its DNA sequence and neural-specific expression pattern authors conclude ror protein related to vertebrate neurotrophin receptors.