DSas-4, Sas4, l(3)s2214
centriolar constituent - required for centriolar assembly, centriole replication, flagellum biogenesis, cilium biogenesis and locomotion - regulates asymmetric cell division
Please see the JBrowse view of Dmel\Sas-4 for information on other features
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Gene model reviewed during 5.47
Low-frequency RNA-Seq exon junction(s) not annotated.
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Sas-4 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signals
View Dmel\Sas-4 in GBrowse 23-48
3-48
3-44.2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
monoclonal
polyclonal
Source for identity of: Sas-4 l(3)s2214
Source for merge of: l(3)s2214 CG10061
Sas-4 is involved in centriole duplication.
RNAi screen using dsRNA made from templates generated with primers directed against this gene results in the spindles that are either anastral (no γ-tubulin staining at the poles) or monastral (only one pole with γ-tubulin staining) when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA.