DopR, dDA1, dumb, DopR1, DA1
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Double stop-codon suppression (UGA, UGA) postulated; FBrf0216884.
Transposon inserted in intron
gene_with_stop_codon_read_through ; SO:0000697
Gene model reviewed during 5.44
Gene model reviewed during 6.02
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Dop1R1 using the Feature Mapper tool.
DopR transcripts appear to be maternally inherited and are abundant in syncytial stages. At these and cellular stages, transcripts are restricted to apical regions of the cortical, peripheral cytoplasm. Later, DopR transcripts are specifically associated with the extending germ band and are excluded from the invaginating posterior mesoderm and the presumptive head regions. DopR transcripts are uniformly distributed in all developing tissues in later stages of embryogenesis.
DopR protein is detected in the ellipsoid body, in the rings innervated by R3 and R4d ring neurons. In the fan-shaped body, strong expression is observed in the dorsal and ventral layers, with weaker labelling observed in the central layers. In the nodulus, strong expression is observed in layers I and II.
GBrowse - Visual display of RNA-Seq signals
View Dmel\Dop1R1 in GBrowse 23-54
3-54
3-52.8
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Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
Source for identity of: DopR CG9652
Source for identity of: Dop1R1 DopR
Certain domains of receptor molecules may vary significantly in different strains of Drosophila but the structural changes do not alter the functional properties of the expressed polypeptides.
A DopR cDNA has been cloned and sequenced.