Low-frequency RNA-Seq exon junction(s) not annotated.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Gene model reviewed during 5.44
1.4 (northern blot)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\rost using the Feature Mapper tool.
rost is expressed in ectodermal and mesodermal cells. The position of segmentally repeated clusters of cells in dorsal, lateral, and ventral regions expressing rost coincide with the position of developing muscle fibers. Reporter construct expression also indicates that rost is expressed in developing muscle cells.
GBrowse - Visual display of RNA-Seq signalsView Dmel\rost in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Shows particularly robust cycling of transcription in adult heads, as assessed by expression analysis using high density oligonucleotide arrays with probe generated during three 12-point time course experiments over the course of 6 days. Shows significant change of expression pattern in circadian mutant background; increased expression in per01, tim01 and ClkJrk background.
Light and electron microscopy are used to study the process of myoblast fusion in rost mutants.
rost has been cloned and sequenced, and its expression pattern has been analysed.
Mutant embryos show fusion of myoblasts to myotubes is largely disturbed leading to the absence of elongated muscle fibres.
The P-element induced mutation shows defects in the fusion of myoblasts to myotubes in the somatic musculature.