T2, pcl, pepsinogen-like, EG:EG0001.1 , scβ
Gene model reviewed during 5.51
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Pgcl using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Pgcl in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Pgcl pcl
Symbol changed from 'pcl' to 'Pgcl' (as of FB2017_04) to reduce confusion with the different gene 'Pcl' (Polycomblike, FBgn0003044). The symbol of 'pcl' (pepsinogen-like) was changed because: (i) it has a much smaller associated literature than 'Pcl' (Polycomblike); and (ii) it seems 'pcl' was originally named based on its homology to the mammalian gene, PGC ('progastricsin', aka 'pepsinogen C'), so including the extra 'g' in the symbol of the fly gene is appropriate.
Transcription unit defined during molecular analysis of the ASC.
The achaete-scute complex defines the basic topology of the sense organ pattern, rather than the type or precise location of the elements. Class B neurons develop when pcl is present, though it is not clear whether or not pcl is sufficient for their development as no genotype exists where pcl is present and all other achaete-scute regions are absent.
A transcription unit in the achaete-scute complex, lying between l(1)sc and ase. It is transcribed from the opposite strand to all four of the genes normally included in the complex, ie 5'--3' = proximal--distal. Its function is poorly understood.