AR, Adrenodoxin reductase
Gene model reviewed during 5.49
There is only one protein coding transcript and one polypeptide associated with this gene
466 (aa); 55 (kD observed)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\dare using the Feature Mapper tool.
dare transcripts are detected in the third instar larval prothoracic gland, and in the adult ovary. Expression in the ovary is limited to nurse cells, and begins at stage 6-7 of oogenesis. Low levels of expression are detected in various adult tissues by in situ hybridization, RT-PCR and RNAse protection experiments.
GBrowse - Visual display of RNA-Seq signalsView Dmel\dare in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Null mutants in dare undergo developmental arrest during the second larval instar stage or at the second larval moult and mutants of intermediate severity are delayed in pupariation. Mild reductions in dare expression cause abnormal behavioural responses to olfactory stimuli. dare mutations of intermediate strength result in rapid, widespread degeneration of the adult nervous system.
Mutant allele show abnormal olfactory behavior.