FlyBase Gene Report: Dmel\lig

FB2025_05 , released December 11, 2025

FB2025_05 , released December 11, 2025

Gene: Dmel\lig

General Information

Symbol

Dmel\lig

Species

D. melanogaster

Name

lingerer

Annotation Symbol

CG8715

Feature Type

protein_coding_gene

FlyBase ID

FBgn0020279

Gene Model Status

Stock Availability

8 publicly available

Gene Summary

lingerer (lig) encodes a putative RNA binding protein that forms a complex with the products of orb and orb2. Loss of lig results in defects in copulation and short-term memory. [Date last reviewed: 2019-03-14] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Pathway
UniProtKB
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

Sequence location

2R:8,067,977..8,078,815 [+]

Recombination map

2-58

RefSeq locus

NT_033778 REGION:8067977..8078815

Sequence

Get Decorated FASTA

Genomic Maps

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (11 terms)

Molecular Function (1 term)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

enables protein binding

inferred from physical interaction with FLYBASE:rin; FB:FBgn0015778

(Baumgartner et al., 2013)

Terms Based on Predictions or Assertions (0 terms)

Biological Process (7 terms)

Terms Based on Experimental Evidence (7 terms)

CV Term

Evidence

References

involved_in copulation

inferred from mutant phenotype

(Kuniyoshi et al., 2002)

involved_in dorsal/ventral axis specification, ovarian follicular epithelium

inferred from genetic interaction with FLYBASE:orb; FB:FBgn0004882

(Costa et al., 2013)

involved_in male mating behavior

inferred from mutant phenotype

(Kuniyoshi et al., 2003)

involved_in negative regulation of imaginal disc growth

inferred from genetic interaction with FLYBASE:yki; FB:FBgn0034970

(Dong et al., 2015)

involved_in negative regulation of receptor signaling pathway via JAK-STAT

inferred from mutant phenotype

(Baumgartner et al., 2013)

involved_in positive regulation of hippo signaling

inferred from mutant phenotype

(Dong et al., 2015)

inferred from genetic interaction with FLYBASE:sav; FB:FBgn0053193

(Dong et al., 2015)

involved_in regulation of gene expression

inferred from mutant phenotype

(Baumgartner et al., 2013)

Terms Based on Predictions or Assertions (0 terms)

Cellular Component (3 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

located_in cytoplasm

inferred from direct assay

(Kuniyoshi et al., 2002)

inferred from direct assay

(Baumgartner et al., 2013, Kuniyoshi et al., 2003)

located_in P-body

inferred from direct assay

(Baumgartner et al., 2013)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

is_active_in cytoplasm

inferred from biological aspect of ancestor with PANTHER:PTN001046274

(GO Reference Genome Project, 2011-)

is_active_in nucleus

inferred from biological aspect of ancestor with PANTHER:PTN001046274

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

Pathway (FlyBase)

NEGATIVE REGULATORS OF JAK-STAT SIGNALING PATHWAY

POSITIVE REGULATORS OF HIPPO SIGNALING PATHWAY

Protein Family (UniProt)

-

Protein Signatures (InterPro)

Summaries

Gene Snapshot

lingerer (lig) encodes a putative RNA binding protein that forms a complex with the products of orb and orb2. Loss of lig results in defects in copulation and short-term memory. [Date last reviewed: 2019-03-14]

Pathway (FlyBase)

NEGATIVE REGULATORS OF JAK-STAT SIGNALING PATHWAY -: Negative regulators of JAK-STAT signaling down-regulate the pathway, attenuating transcriptional control by Stat92E.
POSITIVE REGULATORS OF HIPPO SIGNALING PATHWAY -: The Hippo signaling pathway is an intracellular kinase cascade in which hpo kinase in complex with sav, phosphorylates wts kinase which, in turn, phosphorylates yki transcriptional co-activator leading to its cytosolic retention. Positive regulators of the pathway, enhance the cytosolic retention of yki, negatively regulating tissue growth (Adapted from FBrf0224870).

Protein Function (UniProtKB)

Acts in the nervous system to mediate the control of copulatory organs during courtship.

(UniProt, Q86S05)

Gene Model and Products

Number of Transcripts

12

Number of Unique Polypeptides

8

Please see the JBrowse view of Dmel\lig for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q86S05)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.55

Stop-codon suppression (UAG) postulated; FBrf0216884

Gene model reviewed during 5.44

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.49

Gene model reviewed during 6.02

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

FBtr0088774

5081

1343

FBtr0088775

5117

1332

FBtr0088776

5436

1343

FBtr0100575

4564

1375

FBtr0301915

5048

1332

FBtr0301916

5072

1332

FBtr0301917

5114

1332

FBtr0304681

5042

1330

FBtr0304682

4952

1300

FBtr0330630

5116

1079

FBtr0330631

4835

1417

FBtr0346957

4835

1261

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

FBpp0087852

135.8

1343

7.19

FBpp0087853

134.6

1332

6.91

FBpp0087854

135.8

1343

7.19

FBpp0100030

139.5

1375

6.38

FBpp0291129

134.6

1332

6.91

FBpp0291130

134.6

1332

6.91

FBpp0291131

134.6

1332

6.91

FBpp0293223

134.3

1330

6.91

FBpp0293224

130.7

1300

7.00

FBpp0303480

107.8

1079

6.26

FBpp0303481

144.3

1417

7.22

FBpp0312421

127.5

1261

6.88

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

1343 aa isoforms: lig-PA, lig-PC

1332 aa isoforms: lig-PB, lig-PE, lig-PF, lig-PG

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\lig using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.56

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

late third instar larval stage

larval brain | restricted

• cytoplasm

(Kuniyoshi et al., 2003)

larval ventral nerve cord | subset

• cytoplasm

(Kuniyoshi et al., 2003)

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

lig protein is expressed in a subset of cells in the brain and ventral nerve cord of the late third instar larva.

(Kuniyoshi et al., 2003)

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in cytoplasm

inferred from direct assay

(Kuniyoshi et al., 2002)

inferred from direct assay

(Baumgartner et al., 2013, Kuniyoshi et al., 2003)

located_in P-body

inferred from direct assay

(Baumgartner et al., 2013)

Expression Deduced from Reporters

Reporter: P{lig-GAL4.Elig}

Stage

Tissue/Position (including subcellular localization)

Reference

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\lig in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\lig

View exonic expression by tissue for Dmel\lig

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

35771/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0020279

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0020279

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0020279

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG8715

Flygut - An atlas of the Drosophila adult midgut

FBgn0020279

Images

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 19 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 26 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of lig

Transgenic constructs containing regulatory region of lig

Aberrations (Deficiencies and Duplications) ( 6 )

Inferred from experimentation ( 6 )

Gene disrupted in

(Ryder, 2004.4.26)

(Ryder, 2004.4.26)

(Kuniyoshi et al., 2002)

(Kuniyoshi et al., 2002)

(Kuniyoshi et al., 2002)

Gene not disrupted in

Df(2R)Optix^ΔN

(Li et al., 2013)

Inferred from location ( 8 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal | recessive

lethal - all die before end of pupal stage (with Df(2R)lig^X4)

lethal - all die before end of pupal stage | recessive

lethal - all die during pupal stage, with Scer\GAL4^da.PU

lethal - all die during pupal stage (with Df(2R)Exel7094)

lethal - all die during pupal stage (with lig¹)

lig^PP1

lethal - all die during pupal stage (with lig²)

lig^PP1

lethal - all die during pupal stage (with lig³)

lig^PP1

lethal - all die during pupal stage (with lig^PP1)

partially lethal - majority die (with Df(2R)lig^X4)

lig^P1

partially lethal - majority die (with Df(2R)lig^X13)

lig^P1

partially lethal - majority die (with Df(2R)lig^X18)

lig^P1

partially lethal - majority die (with lig^P1)

partially lethal - majority die (with lig^PP1)

lig^P1

partially lethal - majority die (with lig^PP2)

lig^P1

partially lethal - majority die (with lig^PP3)

lig^P1

partially lethal - majority die (with lig^PP4)

lig^P1

partially lethal - majority die (with lig^PP5)

lig^P1

lig^P1

Sterility

Allele

female semi-fertile

lig^P1

lig^P1

Other Phenotypes

Allele

abnormal locomotor behavior (with Df(2R)lig^X4)

lig^P1

abnormal locomotor behavior (with lig^P1)

lig^PP1

abnormal locomotor behavior (with lig^PP1)

lig^P1

abnormal size, with Scer\GAL4^ey.PH

lig^UAS.WT

abnormal size | adult stage, with Scer\GAL4^nub-AC-62

abnormal size | nutrition conditional, with Scer\GAL4^ey.PH

lig^{R185C.UAS.UTR}

abnormal size | somatic clone

abnormal size | somatic clone | nutrition conditional

lig¹

increased cell death | somatic clone, with Scer\GAL4^Act5C.PI

lig^UAS.WT

some die during pupal stage (with Df(2R)lig^X4)

some die during pupal stage | recessive

Phenotype manifest in

Allele

eye, with Scer\GAL4^ey.PH

lig^UAS.WT

eye | nutrition conditional, with Scer\GAL4^ey.PH

lig^{R185C.UAS.UTR}

eye | somatic clone

ommatidium | somatic clone | increased number

lig¹

wing, with Scer\GAL4^nub-AC-62

lig^PP1

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (2)

10 of 14

Yes

Yes

1

10 of 14

Yes

Yes

1

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (2)

10 of 14

Yes

Yes

9 of 14

No

Yes

Mus musculus (laboratory mouse) (2)

10 of 14

Yes

Yes

10 of 14

Yes

Yes

Xenopus tropicalis (Western clawed frog) (5)

5 of 13

Yes

Yes

5 of 13

Yes

Yes

2 of 13

No

Yes

2 of 13

No

No

1 of 13

No

No

Danio rerio (Zebrafish) (3)

10 of 14

Yes

Yes

10 of 14

Yes

Yes

10 of 14

Yes

Yes

Caenorhabditis elegans (Nematode, roundworm) (1)

2 of 14

Yes

Yes

Anopheles gambiae (African malaria mosquito) (1)

9 of 12

Yes

Yes

Arabidopsis thaliana (thale-cress) (0)

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (1)

1 of 12

Yes

Yes

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:lig. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (0)

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 4 )

Allele

Disease

Interaction

References

ameliorates frontotemporal dementia and/or amyotrophic lateral sclerosis 1

modeled by Zzzz\poly-GA^{80.UAS.Tag:FLAG}

(Markmiller et al., 2018)

ameliorates frontotemporal dementia and/or amyotrophic lateral sclerosis 1

modeled by Zzzz\poly-GA^{80.UAS.Tag:FLAG}

(Markmiller et al., 2018)

exacerbates frontotemporal dementia and/or amyotrophic lateral sclerosis 1

modeled by Zzzz\poly-GR^50.UAS.EGFP

(Lee et al., 2016)

ameliorates amyotrophic lateral sclerosis type 6

modeled by Hsap\FUS^{R521C.UAS.Tag:HA}

(Markmiller et al., 2018)

ameliorates frontotemporal dementia and/or amyotrophic lateral sclerosis 1

modeled by Zzzz\poly-GA^{80.UAS.Tag:FLAG}

(Markmiller et al., 2018)

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

UBAP2; ubiquitin associated protein 2

10 of 14

UBAP2L; ubiquitin associated protein 2 like

10 of 14

NEURODEVELOPMENTAL DISORDER WITH IMPAIRED LANGUAGE, BEHAVIORAL ABNORMALITIES, AND DYSMORPHIC FACIES; NEDLBF

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

anti tag coimmunoprecipitation, peptide massfingerprinting

(Baumgartner et al., 2013)

anti bait coimmunoprecipitation, western blot, coimmunoprecipitation, peptide massfingerprinting, anti tag coimmunoprecipitation, anti tag western blot

(Dong et al., 2015, Kimura et al., 2015, Baumgartner et al., 2013)

pull down, Identification by mass spectrometry

(Fajner et al., 2021)

proximity-dependent biotin identification, Identification by mass spectrometry

(Mannix et al., 2019)

anti bait coimmunoprecipitation, peptide massfingerprinting

(Costa et al., 2005)

anti bait coimmunoprecipitation, western blot, anti tag coimmunoprecipitation

(Kimura et al., 2015)

two hybrid, coimmunoprecipitation, peptide massfingerprinting, anti bait coimmunoprecipitation, western blot, anti tag coimmunoprecipitation, anti tag western blot

(Dong et al., 2015, Kimura et al., 2015, Baumgartner et al., 2013)

anti tag coimmunoprecipitation, anti tag western blot, coimmunoprecipitation, peptide massfingerprinting, western blot

(Dong et al., 2015)

Summary of Genetic Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

suppressible

(Baumgartner et al., 2013)

suppressible

(Baumgartner et al., 2013)

suppressible

(Baumgartner et al., 2013)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

61631

DroID - A comprehensive database of gene and protein interactions.

FBgn0020279

MIST (protein-protein) - An integrated Molecular Interaction Database

35771

Pathways

Signaling Pathways (FlyBase)

NEGATIVE REGULATORS OF JAK-STAT SIGNALING PATHWAY
POSITIVE REGULATORS OF HIPPO SIGNALING PATHWAY

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Class of Gene

gene_with_stop_codon_read_through

(Jungreis et al., 2011)

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

2R

Recombination map

2-58

Cytogenetic map

Sequence location

2R:8,067,977..8,078,815 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

44A4-44A4

Limits computationally determined from genome sequence between P{lacW}CSN4^k08018&P{lacW}l(2)k08504^k08504 and P{lacW}Vps28^k16503

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

44A-44A

(determined by in situ hybridisation)

(Kuniyoshi, 1997.4.17, Kuniyoshi and Yamamoto, 1997)

Map location determined by in situ hybrisation to an unspecified insertion allele of lig.

(Kuniyoshi, 1997.4.17)

Experimentally Determined Recombination Data

Location

2-58

(FlyBase, 2016)

2-57.3

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (8)

Aberrations including deletions of this gene Aberrations including duplications of this gene

43533

w^*; P{GSV1}lig^s-58

61857

y¹ v¹; P{TRiP.HMJ23346}attP40

79317

y¹ w^*; TI{CRIMIC.TG4.2}lig^{CR00848-TG4.2}/SM6a

104231

w^*; P{GawB}lig^NP2528 / CyO

114627

y^d2 w¹¹¹⁸ P{ey-FLP.N}2; P{neoFRT}42D P{SUPor-P}lig^KG08209 /CyO y⁺

HMJ23346

y¹ v¹; P{TRiP.HMJ23346}attP40/CyO

2RG-1605

y² VhaAC39-1^cho-1 v¹; P{U6-lig.NIG.sgRNA}attP40/CyO

v100727

P{KK108129}VIE-260B

Genomic Clones (32)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (178)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

LD45430

Other clones

MIP15115

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0020279

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0020279

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Dong et al., 2015)

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Males carrying a hypomorphic mutation in lig fail to withdraw their genitalia upon termination of copulation, but show no overt abnormalities in their genitalia. Severe disruption of the lig gene results in mutant males that repeatedly attempt copulation but have no successful copulations.

(Kuniyoshi et al., 2002)

Identification: Mutant with defective mating behaviour.

(Kuniyoshi and Yamamoto, 1997)

Males behave normally until the end of copulation when they have difficulty in disconnecting their genitalia after copulation.

(Kuniyoshi and Yamamoto, 1997)

Relationship to Other Genes

Source for database merge of

Source for merge of: lig CG8715

(FlyBase, 1996-)

Additional comments

Source for merge of lig CG8715 was sequence comparison ( date:030120 ).

(FlyBase, 1996-)

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

CG8715

(National Institute of Genetics Fly Stocks, 2022-, Kolkhof et al., 2017, Çiçek et al., 2016, Horan et al., 2015, Costa et al., 2013, Keleman et al., 2009.8.5, Perkins et al., 2009, Costa et al., 2005, Philipps et al., 2004, Giot et al., 2003)

Name Synonyms

Lingerer

(Peng and Gavis, 2022, Wang et al., 2016, Costa et al., 2013)

lingerer

(Geng and MacDonald, 2007, Kuniyoshi et al., 2003, Kuniyoshi and Yamamoto, 1997)

transcription unit A

(Kuniyoshi and Yamamoto, 1997)

Secondary FlyBase IDs

FBgn0033253

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 82 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

35771

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q86S05

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

Q86S05

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q86S05

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

35771/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0020279

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0020279

FlyMine - An integrated database for Drosophila genomics

FBgn0020279

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG8715

MARRVEL_MODEL - MARRVEL (model organism gene)

35771

Linkouts

BioGRID - A database of protein and genetic interactions.

61631

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0020279

DroID - A comprehensive database of gene and protein interactions.

FBgn0020279

DRSC - Results frm RNAi screens

FBgn0020279

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0020279

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0020279

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG8715

Flygut - An atlas of the Drosophila adult midgut

FBgn0020279

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC009024

MIST (protein-protein) - An integrated Molecular Interaction Database

35771

References (81)