FB2021_03, released June 15, 2021

Gene: Dmel\DAAM

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General Information
Symbol
Dmel\DAAM
Species
D. melanogaster
Name
Dishevelled Associated Activator of Morphogenesis
Annotation Symbol
CG14622
Feature Type
protein_coding_gene
FlyBase ID
FBgn0025641
Gene Model Status
Current
Stock Availability
7 publicly available
Gene Summary
Dishevelled Associated Activator of Morphogenesis (DAAM) encodes a formin type of actin assembly factor regulated by Rho GTPases. It plays a role in tracheal tube length regulation, tracheal cuticle pattern formation, growth cone filopodia formation, sarcomerogenesis and axonal growth regulation in embryonic and mushroom body neurons. [Date last reviewed: 2019-03-07] (FlyBase Gene Snapshot)
All Summaries
Also Known As

EG:114D9.2 , dDAAM, Formin

Key Links
Genomic Location
Cytogenetic map
1F2-1F3
Sequence location
X:1,289,713..1,322,362 [-]
Recombination map
1-0.1
RefSeq locus
NC_004354 REGION:1289713..1322362
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (21 terms)
Molecular Function (2 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
enables actin binding
inferred from electronic annotation with InterPro:IPR010472, InterPro:IPR010473
(assigned by InterPro )
(FlyBase Curators et al., 2004-)
enables small GTPase binding
inferred from electronic annotation with InterPro:IPR010473
(assigned by InterPro )
(FlyBase Curators et al., 2004-)
Biological Process (12 terms)
Terms Based on Experimental Evidence (12 terms)
CV Term
Evidence
References
involved_in actin filament bundle assembly
inferred from mutant phenotype
(Matusek et al., 2006)
involved_in axon extension
inferred from genetic interaction with FLYBASE:Frl; FB:FBgn0267795
(Dollar et al., 2016)
inferred from mutant phenotype
(Gombos et al., 2015)
involved_in axon guidance
inferred from mutant phenotype
(Gombos et al., 2015)
involved_in muscle thin filament assembly
inferred from genetic interaction with FLYBASE:Act88F; FB:FBgn0000047
(Molnár et al., 2014)
inferred from genetic interaction with FLYBASE:Tm2; FB:FBgn0004117
(Molnár et al., 2014)
involved_in mushroom body development
inferred from mutant phenotype
(Gombos et al., 2015)
involved_in open tracheal system development
inferred from mutant phenotype
(Matusek et al., 2006)
involved_in positive regulation of actin filament polymerization
inferred from mutant phenotype
(Molnár et al., 2014)
inferred from genetic interaction with FLYBASE:Act88F; FB:FBgn0000047
(Molnár et al., 2014)
inferred from genetic interaction with FLYBASE:Tm2; FB:FBgn0004117
(Molnár et al., 2014)
involved_in positive regulation of filopodium assembly
inferred from mutant phenotype
(Gonçalves-Pimentel et al., 2011)
involved_in positive regulation of sarcomere organization
inferred from genetic interaction with FLYBASE:Act88F; FB:FBgn0000047
(Molnár et al., 2014)
inferred from genetic interaction with FLYBASE:Tm2; FB:FBgn0004117
(Molnár et al., 2014)
involved_in regulation of axonogenesis
inferred from direct assay
(Matusek et al., 2008)
involved_in regulation of filopodium assembly
inferred from direct assay
(Matusek et al., 2008)
involved_in regulation of tube architecture, open tracheal system
inferred from mutant phenotype
(Matusek et al., 2006)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
involved_in positive regulation of actin filament polymerization
inferred from biological aspect of ancestor with PANTHER:PTN002906266
(assigned by GO_Central )
(Gaudet et al., 2011)
Cellular Component (7 terms)
Terms Based on Experimental Evidence (7 terms)
CV Term
Evidence
References
located_in axonal growth cone
inferred from direct assay
(Matusek et al., 2008)
located_in postsynapse
inferred from direct assay
(Migh et al., 2018)
located_in presynapse
inferred from direct assay
(Migh et al., 2018)
located_in presynaptic active zone
inferred from direct assay
(Migh et al., 2018)
located_in sarcoplasm
inferred from direct assay
(Molnár et al., 2014)
located_in striated muscle thin filament
inferred from direct assay
(Molnár et al., 2014)
located_in Z disc
inferred from direct assay
(Molnár et al., 2014)
Terms Based on Predictions or Assertions (0 terms)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Snapshot
Dishevelled Associated Activator of Morphogenesis (DAAM) encodes a formin type of actin assembly factor regulated by Rho GTPases. It plays a role in tracheal tube length regulation, tracheal cuticle pattern formation, growth cone filopodia formation, sarcomerogenesis and axonal growth regulation in embryonic and mushroom body neurons. [Date last reviewed: 2019-03-07]
Summary (Interactive Fly)
Gene Model and Products
Number of Transcripts
6
Number of Unique Polypeptides
3

Please see the JBrowse view of Dmel\DAAM for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Gene model reviewed during 5.51

Low-frequency RNA-Seq exon junction(s) not annotated.

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Gene model reviewed during 5.43

Gene model reviewed during 5.42

Gene model reviewed during 5.55

Sequence Ontology: Class of Gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
DAAM-RA
FBtr0070241
NM_130544
4274
1114
DAAM-RB
FBtr0070239
NM_166876
5365
1153
DAAM-RD
FBtr0303264
NM_001201593
5470
1463
DAAM-RE
FBtr0310282
NM_001272197
5414
1153
DAAM-RF
FBtr0310283
NM_166875
5157
1153
DAAM-RG
FBtr0342731
NM_001297842
5323
1153
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
DAAM-PA
FBpp0070231
125.5
1114
6.97
NP_569900
AAF45600
DAAM-PB
FBpp0070229
129.9
1153
6.90
NP_726724
AAN09040
DAAM-PD
FBpp0292356
162.3
1463
6.81
NP_001188522
ADV37606
DAAM-PE
FBpp0301965
129.9
1153
6.90
NP_001259126
AGB94972
DAAM-PF
FBpp0301966
129.9
1153
6.90
NP_726723
AAF45601
DAAM-PG
FBpp0309599
129.9
1153
6.90
NP_001284771
AHN59242
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

1153 aa isoforms: DAAM-PB, DAAM-PE, DAAM-PF, DAAM-PG
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\DAAM using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 1 -- 3
organism | ubiquitous

Comment: maternally deposited

(Fisher et al., 2012)
embryonic stage 4 -- 6
organism | ubiquitous
(Fisher et al., 2012)
embryonic stage 7 -- 8
head mesoderm
(Fisher et al., 2012)
organism | ubiquitous
(Fisher et al., 2012)
trunk mesoderm
(Fisher et al., 2012)
embryonic stage 9 -- 10
antennal primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
central brain primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
visual primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
dorsal head epidermis primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
lateral head epidermis primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
ventral head epidermis primordium

Comment: reported as procephalic ectoderm primordium

(Fisher et al., 2012)
head mesoderm
(Fisher et al., 2012)
organism | faint | ubiquitous
(Fisher et al., 2012)
trunk mesoderm
(Fisher et al., 2012)
ventral ectoderm
(Fisher et al., 2012)
embryonic stage 11 -- 12
central brain primordium
(Fisher et al., 2012)
dorsal epidermis primordium
(Fisher et al., 2012)
embryonic leading edge cell primordium

Comment: reported as embryonic leading edge cell specific anlage

(Fisher et al., 2012)
head mesoderm
(Fisher et al., 2012)
organism | faint | ubiquitous
(Fisher et al., 2012)
trunk mesoderm
(Fisher et al., 2012)
ventral nerve cord primordium
(Fisher et al., 2012)
embryonic stage 11 -- 13
presumptive embryonic/larval central nervous system
(Matusek et al., 2008)
embryonic stage 13 -- 16
embryonic brain
(Fisher et al., 2012)
embryonic dorsal epidermis
(Fisher et al., 2012)
embryonic esophagus
(Fisher et al., 2012)
embryonic foregut
(Fisher et al., 2012)
embryonic head epidermis
(Fisher et al., 2012)
embryonic leading edge cell
(Fisher et al., 2012)
embryonic ventral epidermis
(Fisher et al., 2012)
embryonic/larval muscle system
(Fisher et al., 2012)
embryonic/larval nervous system
(Fisher et al., 2012)
organism | faint | ubiquitous
(Fisher et al., 2012)
larval ventral nerve cord
(Fisher et al., 2012)
embryonic stage 14 -- 17
embryonic/larval central nervous system
(Matusek et al., 2008)
Additional Descriptive Data

DAAM is expressed pan-neurally in embryos from stage 11.

(Matusek et al., 2008)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 11 -- 13
presumptive embryonic/larval central nervous system
(Matusek et al., 2008)
embryonic stage 14 -- 17
embryonic/larval central nervous system
(Matusek et al., 2008)
first instar larval stage -- wandering third instar larval stage
embryonic/larval hypodermal muscle
(Molnár et al., 2014)
first instar larval stage -- pharate adult stage P8
adult mushroom body gamma-lobe | restricted
(Gombos et al., 2015)
mushroom body vertical lobe
(Gombos et al., 2015)
third instar larval stage
core layer of the larval mushroom body
(Gombos et al., 2015)
wandering third instar larval stage
embryonic/larval hypodermal muscle
(Molnár et al., 2014)
pharate adult stage P8 -- adult stage
indirect flight muscle
• M band
(Molnár et al., 2014)
adult stage
indirect flight muscle
• Z disc
(Molnár et al., 2014)
indirect flight muscle
(Molnár et al., 2014)
neuropil | intense | restricted of adult brain
(Gombos et al., 2015)
adult brain cell body rind | faint
(Gombos et al., 2015)
alpha/beta core Kenyon cell
(Gombos et al., 2015)
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
day 5 of adulthood & male -- day 7 of adulthood & male
spermatozoon
(Wasbrough et al., 2010)
western blot
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
indirect flight muscle
(Molnár et al., 2014)
adult brain
(Gombos et al., 2015)
Additional Descriptive Data

DAAM-protein shows strong expression in the neuropil region of the adult brain. Distinct labeling is observed in the developing and mature mushroom body. In young adults strong labeling in this neuropil region is only observed in the central region of the developing lobes and pedunculus indicating an enrichment in newly projecting axons.

(Gombos et al., 2015)

DAAM protein accumulates in the M band of the IFM from 48 hours APF. In newly eclosed adults, DAAM protein accumulation is weak at the Z disc and prominent at the M band. In four day old adults, DAAM immunoreactivity is equally strong at the M band and the Z disc; DAAM protein also accumulates in the sarcoplasm. At the beginning of the third larval instar (72 hours AEL), DAAM immunoreactivity resolves into two bands along the the M band, while in wandering third instar larvae, some DAAM protein has relocated to a region flanking the Z disc.

(Molnár et al., 2014)

DAAM is expressed pan-neurally in embryos from stage 12.

(Matusek et al., 2008)
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in axonal growth cone
inferred from direct assay
(Matusek et al., 2008)
located_in postsynapse
inferred from direct assay
(Migh et al., 2018)
located_in presynapse
inferred from direct assay
(Migh et al., 2018)
located_in presynaptic active zone
inferred from direct assay
(Migh et al., 2018)
located_in sarcoplasm
inferred from direct assay
(Molnár et al., 2014)
located_in striated muscle thin filament
inferred from direct assay
(Molnár et al., 2014)
located_in Z disc
inferred from direct assay
(Molnár et al., 2014)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\DAAM in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
DRscDB
EMBL-EBI Single Cell Expression Atlas
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyExpress - Embryonic expression images (BDGP data)
  • Stages(s) 7-8
  • Stages(s) 9-10
  • Stages(s) 11-12
  • Stages(s) 13-16
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 22 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 24 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of DAAM
Transgenic constructs containing regulatory region of DAAM
Aberrations (Deficiencies and Duplications) ( 5 )
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal (with DAAMEx1)
lethal (with DAAMEx36)
lethal (with DAAMEx65)
lethal (with DAAMEx68)
lethal (with DAAMEx184)
lethal (with DAAMEx202)
lethal (with DAAMEx249)
lethal | recessive
lethal - all die before end of larval stage, with Scer\GAL4btl.PS
lethal - all die during embryonic stage, with Scer\GAL4elav-C155
partially lethal - majority die
viable
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4btl.PS
viable, with Scer\GAL4Mef2.PR
viable, with Scer\GAL4pnr-MD237
viable, with Scer\GAL4tin.CΔ4
viable (with DAAMEx1)
viable (with DAAMEx65)
viable (with DAAMEx184)
viable (with DAAMEx202)
viable (with DAAMEx249)
Sterility
Allele
fertile
Other Phenotypes
Allele
abnormal locomotor behavior | late third instar larval stage
abnormal locomotor behavior | late third instar larval stage, with Scer\GAL4Mef2.PU
abnormal neuroanatomy
abnormal neuroanatomy, with Scer\GAL4elav-C155
abnormal neuroanatomy, with Scer\GAL4ey-OK107
abnormal neuroanatomy, with Scer\GAL4sca-109-68
abnormal neuroanatomy (with DAAMEx1)
abnormal neuroanatomy (with DAAMEx68)
abnormal neuroanatomy | adult stage
abnormal neuroanatomy | larval stage
abnormal neuroanatomy | somatic clone
abnormal neurophysiology | larval stage, with DAAMEx68, Scer\GAL4btl.PS
abnormal neurophysiology | larval stage, with DAAMUAS.cMb, Scer\GAL4btl.PS
abnormal size | adult stage
abnormal size | larval stage, with Scer\GAL4elav-C155
decreased body size | larval stage
decreased cell number | third instar larval stage, with Scer\GAL4E(spl)m6-BFM.PF
flightless
flightless, with DAAMdsRNA.UAS.T129M, Dcr-2UAS.cDa, Scer\GAL4Hk-UH3
flightless, with DAAMEx1, Dcr-2UAS.cDa, Scer\GAL4Hk-UH3
flightless, with Dcr-2UAS.cDa, Scer\GAL4Hk-UH3
some die during embryonic stage, with Scer\GAL4elav-C155
some die during larval stage, with Scer\GAL4btl.PS
Phenotype manifest in
Allele
A1-7 LL1 motor neuron | larval stage
A1-7 LL1 motor neuron | larval stage, with DAAMEx68, Scer\GAL4btl.PS
A1-7 LL1 motor neuron | larval stage, with DAAMUAS.cMb, Scer\GAL4btl.PS
A1-7 ventral longitudinal muscle 3 | late third instar larval stage
A1-7 ventral longitudinal muscle 3 | late third instar larval stage, with Scer\GAL4Mef2.PU
A1-7 VL3/4 motor neuron | larval stage
abdominal lateral adult muscle precursor cell | third instar larval stage, with Scer\GAL4E(spl)m6-BFM.PF
actin filament bundle | embryonic stage 17
adult mushroom body alpha-lobe
adult mushroom body alpha-lobe | adult stage
adult mushroom body beta-lobe
adult mushroom body beta-lobe | adult stage
axon, with Scer\GAL4elav-C155
axon | adult stage
axon | embryonic stage
connective
connective (with DAAMEx1)
connective (with DAAMEx68)
embryo
embryo (with DAAMEx1)
embryo (with DAAMEx68)
embryonic/larval cuticle
embryonic/larval dorsal trunk | embryonic stage 17
embryonic/larval neuromuscular junction | larval stage
embryonic/larval neuromuscular junction | larval stage, with DAAMEx68, Scer\GAL4btl.PS
embryonic/larval neuromuscular junction | larval stage, with DAAMUAS.cMb, Scer\GAL4btl.PS
embryonic/larval neuromuscular junction | larval stage, with Scer\GAL4elav-C155
embryonic/larval neuromuscular junction | larval stage, with Scer\GAL4Mef2.PR, Scer\GAL4elav-C155
embryonic/larval somatic muscle | late third instar larval stage
embryonic/larval somatic muscle | late third instar larval stage, with Scer\GAL4Mef2.PU
embryonic/larval trachea
embryonic/larval tracheal system
embryonic/larval tracheal system, with Scer\GAL4btl.PS
embryonic/larval tracheal system (with Df(1)AD11)
embryonic somatic muscle
fascicle
fascicle (with DAAMEx1)
fascicle (with DAAMEx68)
fascicle | embryonic stage, with Scer\GAL4elav-C155
filamentous actin
filamentous actin & tracheal fusion cell, with DAAMC.UASp, Scer\GAL4btl.PS
filamentous actin & tracheal fusion cell, with DAAMUASp.cMa, Scer\GAL4btl.PS
filamentous actin & tracheal fusion cell, with Scer\GAL4btl.PS
filamentous actin & tracheolar cell, with Scer\GAL4btl.PS
filopodium (with DAAMEx1)
filopodium (with DAAMEx68)
indirect flight muscle
indirect flight muscle, with DAAMdsRNA.UAS.T129M, Dcr-2UAS.cDa, Scer\GAL4Hk-UH3
indirect flight muscle, with DAAMEx1, Dcr-2UAS.cDa, Scer\GAL4Hk-UH3
larval intersegmental nerve | embryonic stage
larval ventral nerve cord, with Scer\GAL4elav-C155
lateral longitudinal fascicle
lateral longitudinal fascicle (with DAAMEx1)
lateral longitudinal fascicle (with DAAMEx68)
LL1 motor neuron | larval stage, with Scer\GAL4elav-C155
LL1 motor neuron | larval stage, with Scer\GAL4Mef2.PR, Scer\GAL4elav-C155
M band, with DAAMdsRNA.UAS.T129M, Dcr-2UAS.cDa, Scer\GAL4Hk-UH3
M band, with DAAMEx1, Dcr-2UAS.cDa, Scer\GAL4Hk-UH3
microtubule | larval stage, with DAAMEx68, Scer\GAL4btl.PS
microtubule | larval stage, with DAAMUAS.cMb, Scer\GAL4btl.PS
microtubule | larval stage, with Scer\GAL4elav-C155
mushroom body, with Scer\GAL4elav.PU
mushroom body, with Scer\GAL4ey-OK107
mushroom body | somatic clone
mushroom body medial lobe, with Scer\GAL4ey-OK107
mushroom body vertical lobe, with Scer\GAL4ey-OK107
myofibril
myofibril, with DAAMdsRNA.UAS.T129M, Dcr-2UAS.cDa, Scer\GAL4Hk-UH3
myofibril, with DAAMEx1, Dcr-2UAS.cDa, Scer\GAL4Hk-UH3
neurite, with Scer\GAL4elav-C155
neuroblast | somatic clone
neuropil
neuropil (with DAAMEx1)
neuropil (with DAAMEx68)
neuropil | embryonic stage, with Scer\GAL4elav-C155
NMJ bouton | larval stage
NMJ bouton | larval stage, with DAAMEx68, Scer\GAL4btl.PS
NMJ bouton | larval stage, with DAAMUAS.cMb, Scer\GAL4btl.PS
NMJ bouton | larval stage, with Scer\GAL4elav-C155
NMJ bouton | larval stage, with Scer\GAL4Mef2.PR, Scer\GAL4elav-C155
sarcomere
sarcomere, with DAAMdsRNA.UAS.T129M, Dcr-2UAS.cDa, Scer\GAL4Hk-UH3
sarcomere, with DAAMEx1, Dcr-2UAS.cDa, Scer\GAL4Hk-UH3
sarcomere | late third instar larval stage
sarcomere | late third instar larval stage, with Scer\GAL4Mef2.PU
striated muscle myosin thick filament, with DAAMdsRNA.UAS.T129M, Dcr-2UAS.cDa, Scer\GAL4Hk-UH3
striated muscle myosin thick filament, with DAAMEx1, Dcr-2UAS.cDa, Scer\GAL4Hk-UH3
striated muscle thin filament, with DAAMdsRNA.UAS.T129M, Dcr-2UAS.cDa, Scer\GAL4Hk-UH3
striated muscle thin filament, with DAAMEx1, Dcr-2UAS.cDa, Scer\GAL4Hk-UH3
symmetrical commissure | embryonic stage, with Scer\GAL4elav-C155
synaptic vesicle | larval stage
taenidial fold
taenidial fold, with Scer\GAL4btl.PS
taenidial fold | embryonic stage 17
Z disc, with DAAMdsRNA.UAS.T129M, Dcr-2UAS.cDa, Scer\GAL4Hk-UH3
Z disc, with DAAMEx1, Dcr-2UAS.cDa, Scer\GAL4Hk-UH3
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (13)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\DAAM1
15 of 15
Yes
Yes
Hsap\DAAM2
11 of 15
No
Yes
Hsap\DIAPH1
3 of 15
No
No
Hsap\DIAPH2
3 of 15
No
No
Hsap\DIAPH3
3 of 15
No
No
Hsap\GRID2IP
3 of 15
No
Yes
Hsap\INF2
3 of 15
No
No
6  
Hsap\FHDC1
2 of 15
No
No
Hsap\FMNL1
2 of 15
No
No
Hsap\FMN1
1 of 15
No
No
Hsap\FMN2
1 of 15
No
No
Hsap\FMNL2
1 of 15
No
No
Hsap\FMNL3
1 of 15
No
No
1  
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (13)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Daam1
15 of 15
Yes
Yes
 
1  
Mmus\Daam2
11 of 15
No
Yes
Mmus\Diaph1
3 of 15
No
No
Mmus\Diaph2
3 of 15
No
No
Mmus\Diaph3
3 of 15
No
No
Mmus\Grid2ip
3 of 15
No
Yes
Mmus\Inf2
3 of 15
No
No
Mmus\Fhdc1
1 of 15
No
No
Mmus\Fmn1
1 of 15
No
No
Mmus\Fmn2
1 of 15
No
No
Mmus\Fmnl1
1 of 15
No
No
Mmus\Fmnl2
1 of 15
No
No
Mmus\Fmnl3
1 of 15
No
No
Rattus norvegicus (Norway rat) (9)
Rnor\Daam1
11 of 13
Yes
Yes
Rnor\Daam2
4 of 13
No
Yes
Rnor\Diaph1
2 of 13
No
No
Rnor\Diaph2
2 of 13
No
Yes
Rnor\Diaph3
2 of 13
No
No
Rnor\Fhdc1
2 of 13
No
No
Rnor\Grid2ip
2 of 13
No
Yes
Rnor\LOC102547039
2 of 13
No
Yes
Rnor\Inf2
1 of 13
No
Yes
Xenopus tropicalis (Western clawed frog) (14)
Xtro\daam1
8 of 12
Yes
Yes
Xtro\inf2
3 of 12
No
No
Xtro\diaph1
2 of 12
No
No
Xtro\diaph2
2 of 12
No
No
Xtro\diaph3
2 of 12
No
Yes
Xtro\fhdc1
2 of 12
No
No
Xtro\grid2ip
2 of 12
No
Yes
Xtro\LOC100496216
2 of 12
No
Yes
Xtro\LOC101731433
2 of 12
No
Yes
Xtro\fmn1
1 of 12
No
No
Xtro\fmn2
1 of 12
No
No
Xtro\fmnl1
1 of 12
No
No
Xtro\LOC100489883
1 of 12
No
No
Xtro\LOC101733308
1 of 12
No
Yes
Danio rerio (Zebrafish) (23)
Drer\daam1b
14 of 15
Yes
Yes
Drer\daam1a
9 of 15
No
Yes
Drer\daam2
8 of 15
No
Yes
Drer\fhdc4
3 of 15
No
No
Drer\grid2ipb
3 of 15
No
Yes
Drer\diaph2
2 of 15
No
No
Drer\diaph3
2 of 15
No
No
Drer\fhdc1
2 of 15
No
No
Drer\fhdc2
2 of 15
No
No
Drer\fhdc3
2 of 15
No
No
Drer\grid2ipa
2 of 15
No
Yes
Drer\inf2
2 of 15
No
Yes
Drer\LOC101882228
2 of 15
No
Yes
Drer\LOC101886015
2 of 15
No
Yes
Drer\fmn1
1 of 15
No
No
Drer\fmn2a
1 of 15
No
No
Drer\fmn2b
1 of 15
No
No
Drer\fmnl2a
1 of 15
No
No
Drer\LOC100148950
1 of 15
No
Yes
Drer\LOC101882071
1 of 15
No
No
Drer\LOC101882656
1 of 15
No
Yes
Drer\LOC101883438
1 of 15
No
Yes
Drer\LOC101885099
1 of 15
No
Yes
Caenorhabditis elegans (Nematode, roundworm) (6)
Cele\daam-1
12 of 15
Yes
Yes
Cele\cyk-1
3 of 15
No
No
Cele\inft-2
2 of 15
No
No
Cele\exc-6
1 of 15
No
No
Cele\fozi-1
1 of 15
No
No
Cele\frl-1
1 of 15
No
No
Arabidopsis thaliana (thale-cress) (20)
Atha\AFH14
3 of 9
Yes
No
Atha\AFH1
2 of 9
No
Yes
Atha\AT1G59910
2 of 9
No
Yes
Atha\AT2G25050
2 of 9
No
No
Atha\AT2G43800
2 of 9
No
Yes
Atha\AT3G05470
2 of 9
No
Yes
Atha\AT3G07540
2 of 9
No
Yes
Atha\AT3G32400
2 of 9
No
No
Atha\AT5G07650
2 of 9
No
Yes
Atha\AT5G07740
2 of 9
No
No
Atha\AT5G07760
2 of 9
No
Yes
Atha\AT5G07770
2 of 9
No
No
Atha\AT5G48360
2 of 9
No
Yes
Atha\AT5G58160
2 of 9
No
No
Atha\Fh5
2 of 9
No
No
Atha\FH6
2 of 9
No
Yes
Atha\FH8
2 of 9
No
No
Atha\FH19
2 of 9
No
Yes
Atha\AT3G25493
1 of 9
No
Yes
Atha\FH4
1 of 9
No
No
Saccharomyces cerevisiae (Brewer's yeast) (2)
Scer\BNR1
6 of 15
Yes
Yes
Scer\BNI1
5 of 15
No
Yes
Schizosaccharomyces pombe (Fission yeast) (3)
Spom\for3
5 of 12
Yes
Yes
Spom\cdc12
4 of 12
No
Yes
Spom\fus1
3 of 12
No
Yes
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190104 )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00004980
Drosophila simulans
Dsim\GD27915
Drosophila sechellia
Dsec\GM18987
Drosophila erecta
Dere\GG12709
Drosophila yakuba
Dyak\GE16535
Drosophila ananassae
Dana\GF22176
Drosophila pseudoobscura pseudoobscura
Dpse\GA13122
Drosophila persimilis
Dper\GL14390
Drosophila willistoni
Dwil\GK19910
Drosophila virilis
Dvir\GJ15849
Drosophila mojavensis
Dmoj\GI16449
Drosophila grimshawi
Dgri\GH17880
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091500MY )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17026341
Glossina morsitans
Tsetse fly
Gmor\GMOY002551
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_06463
Mayetiola destructor
Hessian fly
Mdes\Mdes012705
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL018268
Anopheles darlingi
American malaria mosquito
Adar\ADAC010399
Anopheles gambiae
Malaria mosquito
Agam\AGAP003292
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ002005
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ002006
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W01Z6 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA008436
Danaus plexippus
Monarch butterfly
Dple\DPOGS201828-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS201827-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL017538
Apis florea
Little honeybee
Aflo\3234916100
Apis mellifera
Western honey bee
Amel\GB42894
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP21571
Bombus terrestris
Buff-tailed bumblebee
Bter\15206803
Linepithema humile
Argentine ant
Lhum\LH20179
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:000433
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG012784
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_03428
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_09468
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_00527
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_01367
Tribolium castaneum
Red flour beetle
Tcas\GLEAN_07082
Pediculus humanus
Human body louse
Phum\PHUM230120
Rhodnius prolixus
Kissing bug
Rpro\RPRC007151
Cimex lectularius
Bed bug
Clec\CLEC002767
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI002207
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_13206
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X01WS )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR012646
Ixodes scapularis
Black-legged tick
Isca\ISCW018883
Stegodyphus mimosarum
African social velvet spider
Smim\KFM79565.1
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_306800
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G02QJ )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Daam1
Strongylocentrotus purpuratus
Purple sea urchin
Spur\SPU_025696gn
Strongylocentrotus purpuratus
Purple sea urchin
Spur\SPU_018783gn
Ciona intestinalis
Vase tunicate
Cint\LOC100184055
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000022004
Gallus gallus
Domestic chicken
Ggal\DAAM1
Gallus gallus
Domestic chicken
Ggal\DAAM2
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (4)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
dia
5 of 10
form3
4 of 10
Frl
3 of 10
capu
2 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 1 )
    Allele
    Disease
    Interaction
    References
    DAAMGD8382
    exacerbates  Machado-Joseph disease
    modeled by Hsap\ATXN3tr.Q78.UAS.Tag:HA
    (Voßfeldt et al., 2012)
    Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    DAAM1; dishevelled associated activator of morphogenesis 1
    15 of 15
    606626
        DAAM2; dishevelled associated activator of morphogenesis 2
        11 of 15
        606627
          DIAPH1; diaphanous related formin 1
          3 of 15
          602121
          DIAPH2; diaphanous related formin 2
          3 of 15
          300108
          DIAPH3; diaphanous related formin 3
          3 of 15
          614567
          GRID2IP; Grid2 interacting protein
          3 of 15
          610639
              INF2; inverted formin 2
              3 of 15
              610982
               
              Functional Complementation Data
              Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
              Dmel gene
              Ortholog showing functional complementation
              Supporting References
              DAAM
              Mmus\Daam1
              (Matusek et al., 2008)
              Interactions
              Summary of Physical Interactions
              esyN Network Diagram
              Show neighbor-neighbor interactions:
              Select Layout:
              Legend:
              Protein
              RNA
              Selected Interactor(s)
              Interactions Browser
              View in Interactions Browser
              Please see the Physical Interaction reports below for full details
              protein-protein
              Physical Interaction
              Assay
              References
              DAAM - Eb1
              anti bait coimmunoprecipitation, anti tag western blot
              (Szikora et al., 2017)
              DAAM - Myo31DF
              anti tag coimmunoprecipitation, anti tag western blot
              (Chougule et al., 2020)
              DAAM - chic
              anti tag coimmunoprecipitation, anti tag western blot
              (Matusek et al., 2008)
              DAAM - dsh
              pull down, anti tag western blot, anti tag coimmunoprecipitation
              (Gombos et al., 2015)
              DAAM - ena
              anti tag coimmunoprecipitation, anti tag western blot
              (Matusek et al., 2008)
              Summary of Genetic Interactions
              esyN Network Diagram
              esyN Network Key:
              Suppression
              Enhancement
              View in Interactions Browser
              Please look at the allele data for full details of the genetic interactions
              Starting gene(s)
              Interaction type
              Interacting gene(s)
              Reference
              DAAM
              enhanceable
              Act88F
              (Molnár et al., 2014)
              DAAM
              suppressible
              Ank2
              (Migh et al., 2018)
              DAAM
              enhanceable
              Ank2
              (Migh et al., 2018)
              DAAM
              enhanceable
              Arpc1
              (Gonçalves-Pimentel et al., 2011)
              DAAM
              enhanceable
              Btk29A
              (Matusek et al., 2006)
              DAAM
              suppressible
              Btk29A
              (Matusek et al., 2006)
              DAAM
              enhanceable
              chic
              (Matusek et al., 2008)
              DAAM
              enhanceable
              dsh
              (Gombos et al., 2015)
              DAAM
              suppressible
              ena
              (Matusek et al., 2008)
              DAAM
              enhanceable
              ena
              (Matusek et al., 2008)
              DAAM
              enhanceable
              Frl
              (Dollar et al., 2016)
              DAAM
              enhanceable
              futsch
              (Migh et al., 2018)
              DAAM
              enhanceable
              fz
              (Gombos et al., 2015)
              Rac1|Rac2|DAAM
              enhanceable
              Mtl
              (Matusek et al., 2008)
              DAAM
              enhanceable
              Mtl|Rac1|Rac2
              (Matusek et al., 2008)
              DAAM
              enhanceable
              pk
              (Gombos et al., 2015)
              DAAM
              enhanceable
              Rac1
              (Gombos et al., 2015, Matusek et al., 2008)
              DAAM
              enhanceable
              Rac1|Rac2
              (Matusek et al., 2008)
              Rac1|DAAM
              enhanceable
              Rac2
              (Matusek et al., 2008)
              DAAM
              enhanceable
              Rho1
              (Matusek et al., 2008, Matusek et al., 2006)
              DAAM
              enhanceable
              Src42A
              (Matusek et al., 2006)
              DAAM
              suppressible
              Src42A
              (Matusek et al., 2006)
              DAAM
              enhanceable
              stan
              (Gombos et al., 2015)
              DAAM
              enhanceable
              Tm2
              (Molnár et al., 2014)
              DAAM
              suppressible
              tmod
              (Molnár et al., 2014)
              DAAM
              enhanceable
              Vang
              (Gombos et al., 2015)
              DAAM
              enhanceable
              Wnt5
              (Gombos et al., 2015)
              Starting gene(s)
              Interaction type
              Interacting gene(s)
              Reference
              Act88F
              enhanceable
              DAAM
              (Molnár et al., 2014)
              Ank2
              suppressible
              DAAM
              (Migh et al., 2018)
              Ank2
              enhanceable
              DAAM
              (Migh et al., 2018)
              Arpc1
              enhanceable
              DAAM
              (Gonçalves-Pimentel et al., 2011)
              dsh
              enhanceable
              DAAM
              (Gombos et al., 2015)
              futsch
              enhanceable
              DAAM
              (Migh et al., 2018)
              tmod
              suppressible
              DAAM
              (Molnár et al., 2014)
              Vang
              suppressible
              DAAM
              (Gombos et al., 2015)
              Wnt5
              suppressible
              DAAM
              (Gombos et al., 2015)
              External Data
              Linkouts
              BioGRID - A database of protein and genetic interactions.
              DroID - A comprehensive database of gene and protein interactions.
              InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
              MIST (genetic) - An integrated Molecular Interaction Database
              MIST (protein-protein) - An integrated Molecular Interaction Database
              Pathways
              Signaling Pathways (FlyBase)
              Metabolic Pathways
              External Data
              Linkouts
              KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
              Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
              Genomic Location and Detailed Mapping Data
              Chromosome (arm)
              X
              Recombination map
              1-0.1
              Cytogenetic map
              1F2-1F3
              Sequence location
              X:1,289,713..1,322,362 [-]
              FlyBase Computed Cytological Location
              Cytogenetic map
              Evidence for location
              1F2-1F3
              Limits computationally determined from genome sequence between P{EP}EP1542 and P{EP}futschEP1419
              Experimentally Determined Cytological Location
              Cytogenetic map
              Notes
              References
              Experimentally Determined Recombination Data
              Location

              1-0.1

              (FlyBase, 2016, Comeron et al., 2012)
              Left of (cM)
              Right of (cM)
              Notes
              Stocks and Reagents
              Stocks (7)
              Genomic Clones (24)
              cDNA Clones (20)
               

              Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

              cDNA clones, fully sequenced
              BDGP DGC clones
              Other clones
              Drosophila Genomics Resource Center cDNA clones

              For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

              cDNA Clones, End Sequenced (ESTs)
              BDGP DGC clones
              Other clones
              RNAi and Array Information
              Linkouts
              DRSC - Results frm RNAi screens
              GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
              Antibody Information
              Laboratory Generated Antibodies
               

              polyclonal

              (Szikora et al., 2020, Szikora et al., 2017)
              Commercially Available Antibodies
               
              Other Information
              Relationship to Other Genes
              Source for database identify of

              Source for identity of: DAAM CG14622

              (Matusek, 2005.9.6)
              Source for database merge of
              Additional comments

              "l(1)G0302" may affect "CG14622".

              (Peter et al., 2002)
              Other Comments

              DAAM is required for thin filament elongation and the actin-assembling activity of DAAM is indispensable for formation of functional muscles. The DAAM protein is enriched at both ends of the thin filaments (at the Z-discs and at the pointed end).

              (Molnár et al., 2014)

              Rho1 is an upstream regulator of DAAM, while Src42A and Btk29A act downstream or in parallel of DAAM.

              (Matusek et al., 2006)

              Appears to be function downstream of Rho1 and upstream of Src42A and Btk29A.

              (Matusek et al., 2005)

              dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.

              (Kiger et al., 2003)
              Origin and Etymology
              Discoverer
              Etymology
              Identification
              External Crossreferences and Linkouts ( 80 )
              Sequence Crossreferences
              NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
              GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
              GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
              RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
              UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
              Other crossreferences
              BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
              Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
              DRscDB
              EMBL-EBI Single Cell Expression Atlas
              Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
              Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
              Flygut - An atlas of the Drosophila adult midgut
              Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
              GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
              iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
              InterPro - A database of protein families, domains and functional sites
              KEGG Genes - Molecular building blocks of life in the genomic space.
              MARRVEL_MODEL
              modMine - A data warehouse for the modENCODE project
              Linkouts
              BioGRID - A database of protein and genetic interactions.
              DroID - A comprehensive database of gene and protein interactions.
              DRSC - Results frm RNAi screens
              FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
              FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
              FlyMine - An integrated database for Drosophila genomics
              Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
              InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
              KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
              MIST (genetic) - An integrated Molecular Interaction Database
              MIST (protein-protein) - An integrated Molecular Interaction Database
              Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
              Synonyms and Secondary IDs (13)
              Reported As
              Symbol Synonym
              CG14622
              (Hosono et al., 2015, Haelterman et al., 2014, Aerts et al., 2010, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Georlette et al., 2007, Zeitlinger et al., 2007, Matusek et al., 2006, Negre et al., 2006, Tanaka et al., 2004, Rogers et al., 2003, Benos, 2000.12.13, Goldstein and Gunawardena, 2000)
              DAAM
              (Kapoor et al., 2021, Ai et al., 2020, Chougule et al., 2020, Meltzer and Schuldiner, 2020.6.25, Parker et al., 2020, Rust et al., 2020, Walls et al., 2020, Tsarouhas et al., 2019, Migh et al., 2018, Vu et al., 2018, Qu et al., 2017, Szikora et al., 2017, Vig et al., 2017, Dollar et al., 2016, Öztürk-Çolak et al., 2016, Öztürk-Çolak et al., 2016, Aradhya et al., 2015, Flores-Benitez and Knust, 2015, Gene Disruption Project members, 2015-, Hosono et al., 2015, Ashwal-Fluss et al., 2014, Chandran et al., 2014, Haelterman et al., 2014, Haelterman et al., 2014.3.25, Yamamoto et al., 2013-, Zhu and Zhang, 2013, Japanese National Institute of Genetics, 2012.5.21, Gonçalves-Pimentel et al., 2011, Napoletano et al., 2011, Aerts et al., 2010, Barkó et al., 2010, Wasbrough et al., 2010, Matusek et al., 2008, Matusek et al., 2006)
              DAAM1
              (Hayashi and Dong, 2017)
              Daam
              (Warner and Longmore, 2009)
              EG:114D9.2
              (Stuart et al., 2007, Giot et al., 2003, Peter et al., 2002, Benos et al., 2001)
              anon-EST:Posey148
              dDAAM
              (Gombos et al., 2015, Molnár et al., 2014, Matusek et al., 2008, Matusek et al., 2005)
              dDaam
              (Nelson et al., 2012)
              daam
              (Bischoff et al., 2021, Pinheiro et al., 2017, Sánchez-Soriano et al., 2010, Leptin, 2005)
              Name Synonyms
              DIA-like
              (Rogers et al., 2003)
              Dishevelled Associated Activator of Morphogenesis
              (Matusek, 2005.9.6, Matusek et al., 2005)
              Dishevelled associated activator of morphogenesis
              (Matusek et al., 2006)
              Formin
              (Cao et al., 2010, Pimentel et al., 2007, Rogers et al., 2003)
              Secondary FlyBase IDs
              • FBgn0027752
              Datasets (0)
              Study focus (0)
              Experimental Role
              Project
              Project Type
              Title
              References (98)